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PHATE: A Dimensionality Reduction Method for Visualizing Trajectory Structures in High-Dimensional Biological Data

Kevin R. Moon, David van Dijk, Zheng Wang, William Chen, Matthew J. Hirn, Ronald R. Coifman, Natalia B. Ivanova, Guy Wolf, Smita Krishnaswamy
doi: https://doi.org/10.1101/120378
Kevin R. Moon
1Departments of Genetics;
2Applied Mathematics Program;
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David van Dijk
5Computational Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
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Zheng Wang
4Yale Stem Cell Center, Department of Genetics, Yale University, New Haven, CT, USA
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William Chen
1Departments of Genetics;
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Matthew J. Hirn
6Department of Computational Mathematics, Science and Engineering;
7Department of Mathematics, Michigan State University, East Lansing, MI, USA
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Ronald R. Coifman
2Applied Mathematics Program;
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Natalia B. Ivanova
4Yale Stem Cell Center, Department of Genetics, Yale University, New Haven, CT, USA
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  • For correspondence: natalia.ivanova@yale.edu
Guy Wolf
2Applied Mathematics Program;
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Smita Krishnaswamy
1Departments of Genetics;
3Department of Computer Science;
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  • For correspondence: smita.krishnaswamy@yale.edu
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Article Information

doi 
https://doi.org/10.1101/120378
History 
  • March 24, 2017.

Article Versions

  • You are currently viewing Version 1 of this article (March 24, 2017 - 15:25).
  • Version 2 (December 1, 2017 - 15:50).
  • Version 3 (June 28, 2018 - 12:03).
  • View Version 4, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Kevin R. Moon1,2†,
  2. David van Dijk5†,
  3. Zheng Wang4†,
  4. William Chen1,
  5. Matthew J. Hirn6,7,
  6. Ronald R. Coifman2,
  7. Natalia B. Ivanova4‡**,
  8. Guy Wolf2‡ and
  9. Smita Krishnaswamy1,3‡*
  1. 1Departments of Genetics;
  2. 2Applied Mathematics Program;
  3. 3Department of Computer Science;
  4. 4Yale Stem Cell Center, Department of Genetics, Yale University, New Haven, CT, USA
  5. 5Computational Biology Program, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
  6. 6Department of Computational Mathematics, Science and Engineering;
  7. 7Department of Mathematics, Michigan State University, East Lansing, MI, USA
  1. ↵*Corresponding author. E-mail: smita.krishnaswamy{at}yale.edu Address: 333 Cedar St, New Haven, CT 06510, USA
  2. ↵**Correspondence for experiments. E-mail: natalia.ivanova{at}yale.edu
  1. ↵† These authors contributed equally.

  2. ↵‡ These authors contributed equally.

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Posted March 24, 2017.
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PHATE: A Dimensionality Reduction Method for Visualizing Trajectory Structures in High-Dimensional Biological Data
Kevin R. Moon, David van Dijk, Zheng Wang, William Chen, Matthew J. Hirn, Ronald R. Coifman, Natalia B. Ivanova, Guy Wolf, Smita Krishnaswamy
bioRxiv 120378; doi: https://doi.org/10.1101/120378
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PHATE: A Dimensionality Reduction Method for Visualizing Trajectory Structures in High-Dimensional Biological Data
Kevin R. Moon, David van Dijk, Zheng Wang, William Chen, Matthew J. Hirn, Ronald R. Coifman, Natalia B. Ivanova, Guy Wolf, Smita Krishnaswamy
bioRxiv 120378; doi: https://doi.org/10.1101/120378

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