Glycosylation flux analysis reveals dynamic changes of intracellular glycosylation flux distribution in Chinese hamster ovary fed-batch cultures

Sandro Hutter; Thomas K. Villiger; David Brühlmann; Matthieu Stettler; Hervé Broly; Miroslav Soos; Rudiyanto Gunawan

doi:10.1101/121517

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Glycosylation flux analysis reveals dynamic changes of intracellular glycosylation flux distribution in Chinese hamster ovary fed-batch cultures

Sandro Hutter, Thomas K. Villiger, David Brühlmann, Matthieu Stettler, Hervé Broly, Miroslav Soos, Rudiyanto Gunawan

doi: https://doi.org/10.1101/121517

Sandro Hutter

aInstitute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland

bSwiss Institute of Bioinformatics, 1015 Lausanne, Switzerland

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Thomas K. Villiger

aInstitute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland

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David Brühlmann

cBiotech Process Sciences, Merck Biopharma, 1804 Corsier-sur-Vevey, Switzerland

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Matthieu Stettler

cBiotech Process Sciences, Merck Biopharma, 1804 Corsier-sur-Vevey, Switzerland

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Hervé Broly

cBiotech Process Sciences, Merck Biopharma, 1804 Corsier-sur-Vevey, Switzerland

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Miroslav Soos

aInstitute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland

dDepartment of Chemical Engineering, University of Chemistry and Technology, 166 28 Prague, Czech Republic

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Rudiyanto Gunawan

aInstitute for Chemical and Bioengineering, Department of Chemistry and Applied Biosciences, ETH Zurich, 8093 Zurich, Switzerland

bSwiss Institute of Bioinformatics, 1015 Lausanne, Switzerland

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For correspondence: rudi.gunawan@chem.ethz.ch

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Posted March 28, 2017.

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Glycosylation flux analysis reveals dynamic changes of intracellular glycosylation flux distribution in Chinese hamster ovary fed-batch cultures

Sandro Hutter, Thomas K. Villiger, David Brühlmann, Matthieu Stettler, Hervé Broly, Miroslav Soos, Rudiyanto Gunawan

bioRxiv 121517; doi: https://doi.org/10.1101/121517

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Glycosylation flux analysis reveals dynamic changes of intracellular glycosylation flux distribution in Chinese hamster ovary fed-batch cultures

Sandro Hutter, Thomas K. Villiger, David Brühlmann, Matthieu Stettler, Hervé Broly, Miroslav Soos, Rudiyanto Gunawan

bioRxiv 121517; doi: https://doi.org/10.1101/121517

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