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Correcting for cell-type heterogeneity in epigenome-wide association studies: premature analyses and conclusions
Shijie C Zheng, Stephan Beck, Andrew E. Jaffe, Devin C. Koestler, Kasper D. Hansen, Andres E. Houseman, Rafael A. Irizarry, Martin Widschwendter, Andrew E. Teschendorff
doi: https://doi.org/10.1101/121533
Shijie C Zheng
1CAS Key Lab of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
2University of Chinese Academy of Sciences, 19A Yuquan Road, Beijing, China.
Stephan Beck
3Medical Genomics, Paul O’Gorman Building, UCL Cancer Institute, University College London, 72 Huntley Street, London, United Kingdom.
Andrew E. Jaffe
4Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
5Center for Computational Biology, Johns Hopkins University, Baltimore, Maryland, United States of America.
Devin C. Koestler
6Department of Biostatistics, University of Kansas Medical Center, Kansas City, KS, USA.
Kasper D. Hansen
7Center for Epigenetics, Johns Hopkins University School of Medicine, USA.
8McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, USA.
9Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, USA.
Andres E. Houseman
10School of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA.
Rafael A. Irizarry
11Department of Biostatistics and Computational Biology, Dana Farber Cancer Institute, USA.
12Department of Biostatistics, Harvard T.H. Chan School of Public Health, USA.
Martin Widschwendter
13Statistical Cancer Genomics, Paul O’Gorman Building, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, United Kingdom.
Andrew E. Teschendorff
1CAS Key Lab of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
13Statistical Cancer Genomics, Paul O’Gorman Building, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, United Kingdom.
14Department of Women’s Cancer, University College London, 74 Huntley Street, London, United Kingdom.
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Posted March 28, 2017.
Correcting for cell-type heterogeneity in epigenome-wide association studies: premature analyses and conclusions
Shijie C Zheng, Stephan Beck, Andrew E. Jaffe, Devin C. Koestler, Kasper D. Hansen, Andres E. Houseman, Rafael A. Irizarry, Martin Widschwendter, Andrew E. Teschendorff
bioRxiv 121533; doi: https://doi.org/10.1101/121533
Correcting for cell-type heterogeneity in epigenome-wide association studies: premature analyses and conclusions
Shijie C Zheng, Stephan Beck, Andrew E. Jaffe, Devin C. Koestler, Kasper D. Hansen, Andres E. Houseman, Rafael A. Irizarry, Martin Widschwendter, Andrew E. Teschendorff
bioRxiv 121533; doi: https://doi.org/10.1101/121533
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