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Environmental cystine drives glutamine anaplerosis and sensitizes cells to glutaminase inhibition

View ORCID ProfileAlexander Muir, View ORCID ProfileLaura V. Danai, Dan Y. Gui, Chiara Y. Waingarten, Matthew G. Vander Heiden
doi: https://doi.org/10.1101/126631
Alexander Muir
1Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
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  • ORCID record for Alexander Muir
Laura V. Danai
1Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
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  • ORCID record for Laura V. Danai
Dan Y. Gui
1Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
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Chiara Y. Waingarten
1Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
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Matthew G. Vander Heiden
1Koch Institute for Integrative Cancer Research and Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
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  • For correspondence: mvh@mit.edu
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Posted April 11, 2017.
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Environmental cystine drives glutamine anaplerosis and sensitizes cells to glutaminase inhibition
Alexander Muir, Laura V. Danai, Dan Y. Gui, Chiara Y. Waingarten, Matthew G. Vander Heiden
bioRxiv 126631; doi: https://doi.org/10.1101/126631
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Environmental cystine drives glutamine anaplerosis and sensitizes cells to glutaminase inhibition
Alexander Muir, Laura V. Danai, Dan Y. Gui, Chiara Y. Waingarten, Matthew G. Vander Heiden
bioRxiv 126631; doi: https://doi.org/10.1101/126631

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