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Topological demarcation by HMGB2 is disrupted early upon senescence entry across cell types and induces CTCF clustering
Anne Zirkel, Milos Nikolic, Konstantinos Sofiadis, Jan-Philipp Mallm, Lilija Brant, Christian Becker, Janine Altmüller, Julia Franzen, Mirjam Koker, Eduardo G Gusmao, Ivan G Costa, Roland T Ullrich, Wolfgang Wagner, Peter Nürnberg, Karsten Rippe, Argyris Papantonis
doi: https://doi.org/10.1101/127522
Anne Zirkel
1Center for Molecular Medicine, University of Cologne, 50931 Cologne, Germany
Milos Nikolic
1Center for Molecular Medicine, University of Cologne, 50931 Cologne, Germany
Konstantinos Sofiadis
1Center for Molecular Medicine, University of Cologne, 50931 Cologne, Germany
Jan-Philipp Mallm
2German Cancer Research Center & Bioquant, 69120 Heidelberg, Germany
Lilija Brant
1Center for Molecular Medicine, University of Cologne, 50931 Cologne, Germany
Christian Becker
3Cologne Center for Genomics, University of Cologne, 50931 Cologne, Germany
Janine Altmüller
1Center for Molecular Medicine, University of Cologne, 50931 Cologne, Germany
3Cologne Center for Genomics, University of Cologne, 50931 Cologne, Germany
Julia Franzen
4Helmholtz Institute for Biomedical Engineering, RWTH Aachen University Medical School, 52074 Aachen, Germany
Mirjam Koker
5Clinic I of Internal Medicine & Center for Integrated Oncology, University Hospital Cologne, 50931 Cologne, Germany
Eduardo G Gusmao
6Interdisciplinary Centre for Clinical Research, RWTH Aachen University Medical School, 52062 Aachen, Germany
7Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard T.H. Chan School of Public Health, MA 02215 Boston, USA
Ivan G Costa
6Interdisciplinary Centre for Clinical Research, RWTH Aachen University Medical School, 52062 Aachen, Germany
Roland T Ullrich
1Center for Molecular Medicine, University of Cologne, 50931 Cologne, Germany
5Clinic I of Internal Medicine & Center for Integrated Oncology, University Hospital Cologne, 50931 Cologne, Germany
Wolfgang Wagner
4Helmholtz Institute for Biomedical Engineering, RWTH Aachen University Medical School, 52074 Aachen, Germany
Peter Nürnberg
1Center for Molecular Medicine, University of Cologne, 50931 Cologne, Germany
3Cologne Center for Genomics, University of Cologne, 50931 Cologne, Germany
8Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany
Karsten Rippe
2German Cancer Research Center & Bioquant, 69120 Heidelberg, Germany
Argyris Papantonis
1Center for Molecular Medicine, University of Cologne, 50931 Cologne, Germany
Article usage
Posted April 14, 2017.
Topological demarcation by HMGB2 is disrupted early upon senescence entry across cell types and induces CTCF clustering
Anne Zirkel, Milos Nikolic, Konstantinos Sofiadis, Jan-Philipp Mallm, Lilija Brant, Christian Becker, Janine Altmüller, Julia Franzen, Mirjam Koker, Eduardo G Gusmao, Ivan G Costa, Roland T Ullrich, Wolfgang Wagner, Peter Nürnberg, Karsten Rippe, Argyris Papantonis
bioRxiv 127522; doi: https://doi.org/10.1101/127522
Topological demarcation by HMGB2 is disrupted early upon senescence entry across cell types and induces CTCF clustering
Anne Zirkel, Milos Nikolic, Konstantinos Sofiadis, Jan-Philipp Mallm, Lilija Brant, Christian Becker, Janine Altmüller, Julia Franzen, Mirjam Koker, Eduardo G Gusmao, Ivan G Costa, Roland T Ullrich, Wolfgang Wagner, Peter Nürnberg, Karsten Rippe, Argyris Papantonis
bioRxiv 127522; doi: https://doi.org/10.1101/127522
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