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Disabling Cas9 by an anti-CRISPR DNA mimic

Jiyung Shing, Fuguo Jiang, Jun-Jie Liu, Nicholas L. Bray, Benjamin J. Rauch, Seung Hyun Baik, Eva Nogales, Joseph Bondy-Denomy, View ORCID ProfileJacob E. Corn, Jennifer A. Doudna
doi: https://doi.org/10.1101/129627
Jiyung Shing
1Innovative Genomics Institute, Berkeley, California 94720
2Department of Molecular and Cell Biology, University of California, Berkeley, California 94720
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Fuguo Jiang
2Department of Molecular and Cell Biology, University of California, Berkeley, California 94720
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Jun-Jie Liu
2Department of Molecular and Cell Biology, University of California, Berkeley, California 94720
5Department of Chemistry, University of California, Berkeley, California 94720
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Nicholas L. Bray
1Innovative Genomics Institute, Berkeley, California 94720
2Department of Molecular and Cell Biology, University of California, Berkeley, California 94720
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Benjamin J. Rauch
3Department of Microbiology and Immunology, and Quantitative Biosciences Institute, University of California, San Francisco, CA 94158
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Seung Hyun Baik
1Innovative Genomics Institute, Berkeley, California 94720
2Department of Molecular and Cell Biology, University of California, Berkeley, California 94720
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Eva Nogales
2Department of Molecular and Cell Biology, University of California, Berkeley, California 94720
5Department of Chemistry, University of California, Berkeley, California 94720
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Joseph Bondy-Denomy
3Department of Microbiology and Immunology, and Quantitative Biosciences Institute, University of California, San Francisco, CA 94158
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Jacob E. Corn
1Innovative Genomics Institute, Berkeley, California 94720
2Department of Molecular and Cell Biology, University of California, Berkeley, California 94720
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  • ORCID record for Jacob E. Corn
  • For correspondence: jcorn@berkeley.edu doudna@berkeley.edu
Jennifer A. Doudna
1Innovative Genomics Institute, Berkeley, California 94720
2Department of Molecular and Cell Biology, University of California, Berkeley, California 94720
4Howard Hughes Medical Institute, Berkeley, California 94720
5Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720
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  • For correspondence: jcorn@berkeley.edu doudna@berkeley.edu
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Article Information

doi 
https://doi.org/10.1101/129627
History 
  • April 23, 2017.

Article Versions

  • Version 1 (April 22, 2017 - 13:05).
  • You are viewing Version 2, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY 4.0 International license.

Author Information

  1. Jiyung Shing1,2*,
  2. Fuguo Jiang2*,
  3. Jun-Jie Liu2,5*,
  4. Nicholas L. Bray1,2,
  5. Benjamin J. Rauch3,
  6. Seung Hyun Baik1,2,
  7. Eva Nogales2,5,
  8. Joseph Bondy-Denomy3,
  9. Jacob E. Corn1,2,† and
  10. Jennifer A. Doudna1,2,4,5,†
  1. 1Innovative Genomics Institute, Berkeley, California 94720
  2. 2Department of Molecular and Cell Biology, University of California, Berkeley, California 94720
  3. 3Department of Microbiology and Immunology, and Quantitative Biosciences Institute, University of California, San Francisco, CA 94158
  4. 4Howard Hughes Medical Institute, Berkeley, California 94720
  5. 5Department of Chemistry, University of California, Berkeley, California 94720
  6. 5Molecular Biophysics and Integrated Bioimaging Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720
  1. ↵†Correspondence should be addressed to J.E.C. (jcorn{at}berkeley.edu) and J.A.D. (doudna{at}berkeley.edu)
  1. ↵* These authors contributed equally to the project.

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Disabling Cas9 by an anti-CRISPR DNA mimic
Jiyung Shing, Fuguo Jiang, Jun-Jie Liu, Nicholas L. Bray, Benjamin J. Rauch, Seung Hyun Baik, Eva Nogales, Joseph Bondy-Denomy, Jacob E. Corn, Jennifer A. Doudna
bioRxiv 129627; doi: https://doi.org/10.1101/129627
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Disabling Cas9 by an anti-CRISPR DNA mimic
Jiyung Shing, Fuguo Jiang, Jun-Jie Liu, Nicholas L. Bray, Benjamin J. Rauch, Seung Hyun Baik, Eva Nogales, Joseph Bondy-Denomy, Jacob E. Corn, Jennifer A. Doudna
bioRxiv 129627; doi: https://doi.org/10.1101/129627

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