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Bayesian Integrated analysis of multiple types of rare variants to infer risk genes for schizophrenia and other neurodevelopmental disorders
Hoang T Nguyen, Amanda Dobbyn, Laura M Huckins, View ORCID ProfileDouglas M Ruderfer, Gulio Genovese, Menachem Fromer, Xinyi Xu, Joseph Buxbaum, Christina Hultman, View ORCID ProfilePamela Sklar, Shaun M Purcell, Xin He, Patrick F Sullivan, View ORCID ProfileEli A Stahl
doi: https://doi.org/10.1101/135293
Hoang T Nguyen
1Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Amanda Dobbyn
1Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Laura M Huckins
1Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Douglas M Ruderfer
1Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
2Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN 37235, USA.
Gulio Genovese
3Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
4Department of Genetics, Harvard Medical School, Massachusetts, USA.
Menachem Fromer
1Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
5Verily Life Sciences, USA.
Xinyi Xu
6Seaver Autism Center, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Joseph Buxbaum
6Seaver Autism Center, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
Christina Hultman
7Department of Medical Epidemiology and Biostatistics, Karolinska Instituet, Stockholm, Sweden.
Pamela Sklar
1Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
3Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Shaun M Purcell
1Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
3Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
8Sleep Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Xin He
9Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.
Patrick F Sullivan
7Department of Medical Epidemiology and Biostatistics, Karolinska Instituet, Stockholm, Sweden.
10Departments of Genetics and Psychiatry, University of North Carolina, Chapel Hill, North Carolina 27599-7264, USA.
Eli A Stahl
1Division of Psychiatric Genomics, Department of Genetics and Genomic Sciences, Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.
3Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Posted May 08, 2017.
Bayesian Integrated analysis of multiple types of rare variants to infer risk genes for schizophrenia and other neurodevelopmental disorders
Hoang T Nguyen, Amanda Dobbyn, Laura M Huckins, Douglas M Ruderfer, Gulio Genovese, Menachem Fromer, Xinyi Xu, Joseph Buxbaum, Christina Hultman, Pamela Sklar, Shaun M Purcell, Xin He, Patrick F Sullivan, Eli A Stahl
bioRxiv 135293; doi: https://doi.org/10.1101/135293
Bayesian Integrated analysis of multiple types of rare variants to infer risk genes for schizophrenia and other neurodevelopmental disorders
Hoang T Nguyen, Amanda Dobbyn, Laura M Huckins, Douglas M Ruderfer, Gulio Genovese, Menachem Fromer, Xinyi Xu, Joseph Buxbaum, Christina Hultman, Pamela Sklar, Shaun M Purcell, Xin He, Patrick F Sullivan, Eli A Stahl
bioRxiv 135293; doi: https://doi.org/10.1101/135293
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