Tacrolimus rescues endothelial ALK1 loss-of-function signaling and improves HHT vascular pathology

Santiago Ruiz; Pallavi Chandakkar; Haitian Zhao; Julien Papoin; Prodyot K. Chatterjee; Erica Christen; Christine N. Metz; Lionel Blanc; Fabien Campagne; Philippe Marambaud

doi:10.1101/137737

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Tacrolimus rescues endothelial ALK1 loss-of-function signaling and improves HHT vascular pathology

View ORCID ProfileSantiago Ruiz, Pallavi Chandakkar, Haitian Zhao, Julien Papoin, Prodyot K. Chatterjee, Erica Christen, View ORCID ProfileChristine N. Metz, View ORCID ProfileLionel Blanc, View ORCID ProfileFabien Campagne, View ORCID ProfilePhilippe Marambaud

doi: https://doi.org/10.1101/137737

Santiago Ruiz

1Litwin-Zucker Research Center for the Study of Alzheimer’s Disease, The Feinstein Institute for Medical Research, Manhasset, NY, USA

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ORCID record for Santiago Ruiz

Pallavi Chandakkar

1Litwin-Zucker Research Center for the Study of Alzheimer’s Disease, The Feinstein Institute for Medical Research, Manhasset, NY, USA

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Haitian Zhao

1Litwin-Zucker Research Center for the Study of Alzheimer’s Disease, The Feinstein Institute for Medical Research, Manhasset, NY, USA

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Julien Papoin

2Center for Autoimmune and Musculoskeletal Disorders, The Feinstein Institute for Medical Research, Manhasset, NY, USA

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Prodyot K. Chatterjee

3Center for Biomedical Science, The Feinstein Institute for Medical Research, Manhasset, NY, USA

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Erica Christen

1Litwin-Zucker Research Center for the Study of Alzheimer’s Disease, The Feinstein Institute for Medical Research, Manhasset, NY, USA

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Christine N. Metz

3Center for Biomedical Science, The Feinstein Institute for Medical Research, Manhasset, NY, USA

4Hofstra Northwell School of Medicine, Hempstead, NY, USA

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Lionel Blanc

2Center for Autoimmune and Musculoskeletal Disorders, The Feinstein Institute for Medical Research, Manhasset, NY, USA

4Hofstra Northwell School of Medicine, Hempstead, NY, USA

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ORCID record for Lionel Blanc

Fabien Campagne

5The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, The Weill Cornell Medical College, New York, NY, USA

6Department of Physiology and Biophysics, The Weill Cornell Medical College, New York, NY, USA

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Philippe Marambaud

1Litwin-Zucker Research Center for the Study of Alzheimer’s Disease, The Feinstein Institute for Medical Research, Manhasset, NY, USA

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ORCID record for Philippe Marambaud
For correspondence: PMaramba@northwell.edu

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Posted May 13, 2017.

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Tacrolimus rescues endothelial ALK1 loss-of-function signaling and improves HHT vascular pathology

Santiago Ruiz, Pallavi Chandakkar, Haitian Zhao, Julien Papoin, Prodyot K. Chatterjee, Erica Christen, Christine N. Metz, Lionel Blanc, Fabien Campagne, Philippe Marambaud

bioRxiv 137737; doi: https://doi.org/10.1101/137737

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Tacrolimus rescues endothelial ALK1 loss-of-function signaling and improves HHT vascular pathology

Santiago Ruiz, Pallavi Chandakkar, Haitian Zhao, Julien Papoin, Prodyot K. Chatterjee, Erica Christen, Christine N. Metz, Lionel Blanc, Fabien Campagne, Philippe Marambaud

bioRxiv 137737; doi: https://doi.org/10.1101/137737

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