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Axe: rapid, competitive sequence read demultiplexing using a trie

View ORCID ProfileKevin D. Murray, View ORCID ProfileJustin O. Borevitz
doi: https://doi.org/10.1101/160606
Kevin D. Murray
1ARC Centre of Excellence in Plant Energy Biology, Research School of Biology, ANU, Canberra, Australia
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Justin O. Borevitz
1ARC Centre of Excellence in Plant Energy Biology, Research School of Biology, ANU, Canberra, Australia
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Abstract

Here we implement a rapid algorithm for demultiplexing DNA sequence reads with in-read indices. Axe selects the optimal index present in a sequence read, even in the presence of sequencing errors. The algorithm is able to handle combinatorial indexing, indices of differing length, and several mismatches per index sequence.

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Posted July 07, 2017.
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Axe: rapid, competitive sequence read demultiplexing using a trie
Kevin D. Murray, Justin O. Borevitz
bioRxiv 160606; doi: https://doi.org/10.1101/160606
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Axe: rapid, competitive sequence read demultiplexing using a trie
Kevin D. Murray, Justin O. Borevitz
bioRxiv 160606; doi: https://doi.org/10.1101/160606

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