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Quantius: Generic, high-fidelity human annotation of scientific images at 105-clicks-per-hour

View ORCID ProfileAlex J. Hughes, Joseph D. Mornin, View ORCID ProfileSujoy K. Biswas, David P. Bauer, Simone Bianco, View ORCID ProfileZev J. Gartner
doi: https://doi.org/10.1101/164087
Alex J. Hughes
1Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA.
2Center for Cellular Construction, University of California, San Francisco, CA, USA.
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Joseph D. Mornin
3Independent researcher, San Francisco, CA, USA.
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Sujoy K. Biswas
2Center for Cellular Construction, University of California, San Francisco, CA, USA.
4Department of Industrial and Applied Genomics, IBM Accelerated Discovery Laboratory, IBM Almaden Research Center, San Jose, CA, USA.
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David P. Bauer
2Center for Cellular Construction, University of California, San Francisco, CA, USA.
5Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA, USA.
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Simone Bianco
2Center for Cellular Construction, University of California, San Francisco, CA, USA.
4Department of Industrial and Applied Genomics, IBM Accelerated Discovery Laboratory, IBM Almaden Research Center, San Jose, CA, USA.
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Zev J. Gartner
1Department of Pharmaceutical Chemistry, University of California, San Francisco, CA, USA.
2Center for Cellular Construction, University of California, San Francisco, CA, USA.
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Abstract

We describe Quantius, a crowd-based image annotation platform that provides an accurate alternative to task-specific computational algorithms for difficult image analysis problems. We use Quantius to quantify a variety of computationally challenging medium-throughput tasks with ~50x and 30x savings in analysis time and cost respectively, relative to a single expert annotator. We show equivalent deep learning performance for Quantius- and expert-derived annotations, bridging towards scalable integration with tailored machine-learning algorithms.

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
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Posted July 15, 2017.
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Quantius: Generic, high-fidelity human annotation of scientific images at 105-clicks-per-hour
Alex J. Hughes, Joseph D. Mornin, Sujoy K. Biswas, David P. Bauer, Simone Bianco, Zev J. Gartner
bioRxiv 164087; doi: https://doi.org/10.1101/164087
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Quantius: Generic, high-fidelity human annotation of scientific images at 105-clicks-per-hour
Alex J. Hughes, Joseph D. Mornin, Sujoy K. Biswas, David P. Bauer, Simone Bianco, Zev J. Gartner
bioRxiv 164087; doi: https://doi.org/10.1101/164087

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