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PIK3CAH1047R-induced paradoxical ERK activation results in resistance to BRAFV600E specific inhibitors in BRAFV600E PIK3CAH1047R double mutant thyroid tumors
Matthias A. Roelli, Dorothée Ruffieux-Daidié, Amandine Stooss, Oussama ElMokh, Wayne A. Phillips, Matthias S. Dettmer, View ORCID ProfileRoch-Philippe Charles
doi: https://doi.org/10.1101/164533
Matthias A. Roelli
1Institut für Biochemie und Molekulare Medizin, Universität Bern, Bern, Switzerland
Dorothée Ruffieux-Daidié
1Institut für Biochemie und Molekulare Medizin, Universität Bern, Bern, Switzerland
Amandine Stooss
1Institut für Biochemie und Molekulare Medizin, Universität Bern, Bern, Switzerland
Oussama ElMokh
1Institut für Biochemie und Molekulare Medizin, Universität Bern, Bern, Switzerland
Wayne A. Phillips
3Cancer Biology Laboratory, Peter MacCallum Cancer Centre, Melbourne, Australia
Matthias S. Dettmer
2Institut für Pathologie, Universität Bern, Bern, Switzerland
Roch-Philippe Charles
1Institut für Biochemie und Molekulare Medizin, Universität Bern, Bern, Switzerland

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Posted July 18, 2017.
PIK3CAH1047R-induced paradoxical ERK activation results in resistance to BRAFV600E specific inhibitors in BRAFV600E PIK3CAH1047R double mutant thyroid tumors
Matthias A. Roelli, Dorothée Ruffieux-Daidié, Amandine Stooss, Oussama ElMokh, Wayne A. Phillips, Matthias S. Dettmer, Roch-Philippe Charles
bioRxiv 164533; doi: https://doi.org/10.1101/164533
PIK3CAH1047R-induced paradoxical ERK activation results in resistance to BRAFV600E specific inhibitors in BRAFV600E PIK3CAH1047R double mutant thyroid tumors
Matthias A. Roelli, Dorothée Ruffieux-Daidié, Amandine Stooss, Oussama ElMokh, Wayne A. Phillips, Matthias S. Dettmer, Roch-Philippe Charles
bioRxiv 164533; doi: https://doi.org/10.1101/164533
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