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Estimating inflation in GWAS summary statistics due to variance distortion from cryptic relatedness
Dominic Holland, Chun-Chieh Fan, Oleksandr Frei, Alexey A. Shadrin, Olav B. Smeland, V. S. Sundar, Ole A. Andreassen, Anders M. Dale
doi: https://doi.org/10.1101/164939
Dominic Holland
a Center for Multimodal Imaging and Genetics, University of California at San Diego, La Jolla, CA 92037, USA
b Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA
Chun-Chieh Fan
a Center for Multimodal Imaging and Genetics, University of California at San Diego, La Jolla, CA 92037, USA
c Department of Cognitive Sciences, University of California at San Diego, La Jolla, CA 92093, USA
d Department of Radiology, University of California, San Diego, La Jolla, CA 92093, USA
Oleksandr Frei
e NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo 0424 Oslo, Norway
Alexey A. Shadrin
e NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo 0424 Oslo, Norway
Olav B. Smeland
e NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo 0424 Oslo, Norway
f Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
a Center for Multimodal Imaging and Genetics, University of California at San Diego, La Jolla, CA 92037, USA
V. S. Sundar
a Center for Multimodal Imaging and Genetics, University of California at San Diego, La Jolla, CA 92037, USA
d Department of Radiology, University of California, San Diego, La Jolla, CA 92093, USA
Ole A. Andreassen
e NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo 0424 Oslo, Norway
f Division of Mental Health and Addiction, Oslo University Hospital, 0407 Oslo, Norway
Anders M. Dale
a Center for Multimodal Imaging and Genetics, University of California at San Diego, La Jolla, CA 92037, USA
b Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA
d Department of Radiology, University of California, San Diego, La Jolla, CA 92093, USA
g Department of Psychiatry, University of California, San Diego, La Jolla, CA 92093, USA
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Posted July 21, 2017.
Estimating inflation in GWAS summary statistics due to variance distortion from cryptic relatedness
Dominic Holland, Chun-Chieh Fan, Oleksandr Frei, Alexey A. Shadrin, Olav B. Smeland, V. S. Sundar, Ole A. Andreassen, Anders M. Dale
bioRxiv 164939; doi: https://doi.org/10.1101/164939
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