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Correcting batch effects in single-cell RNA sequencing data by matching mutual nearest neighbours

Laleh Haghverdi, View ORCID ProfileAaron T. L. Lun, View ORCID ProfileMichael D. Morgan, View ORCID ProfileJohn C. Marioni
doi: https://doi.org/10.1101/165118
Laleh Haghverdi
1European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom
2Institute of Computational Biology, Helmholtz Zentrum München, 85764 Neuherberg, Germany
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Aaron T. L. Lun
3Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Li Ka Shing Centre, Cambridge CB2 0RE, United Kingdom
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Michael D. Morgan
4Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
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John C. Marioni
1European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom
3Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Li Ka Shing Centre, Cambridge CB2 0RE, United Kingdom
4Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
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Article Information

doi 
https://doi.org/10.1101/165118
History 
  • July 18, 2017.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.

Author Information

  1. Laleh Haghverdi1,2,
  2. Aaron T. L. Lun3,
  3. Michael D. Morgan4 and
  4. John C. Marioni1,3,4
  1. 1European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom
  2. 2Institute of Computational Biology, Helmholtz Zentrum München, 85764 Neuherberg, Germany
  3. 3Cancer Research UK Cambridge Institute, University of Cambridge, Robinson Way, Li Ka Shing Centre, Cambridge CB2 0RE, United Kingdom
  4. 4Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, United Kingdom
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Posted July 18, 2017.
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Correcting batch effects in single-cell RNA sequencing data by matching mutual nearest neighbours
Laleh Haghverdi, Aaron T. L. Lun, Michael D. Morgan, John C. Marioni
bioRxiv 165118; doi: https://doi.org/10.1101/165118
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Correcting batch effects in single-cell RNA sequencing data by matching mutual nearest neighbours
Laleh Haghverdi, Aaron T. L. Lun, Michael D. Morgan, John C. Marioni
bioRxiv 165118; doi: https://doi.org/10.1101/165118

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