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NmeCas9 is an intrinsically high-fidelity genome editing platform
Nadia Amrani, Xin D. Gao, Pengpeng Liu, Ankit Gupta, Alireza Edraki, Raed Ibraheim, Kanae E. Sasaki, View ORCID ProfileLihua Julie Zhu, Scot A. Wolfe, View ORCID ProfileErik J. Sontheimer
doi: https://doi.org/10.1101/172650
Nadia Amrani
1RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
Xin D. Gao
1RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
Pengpeng Liu
3Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
4Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
Ankit Gupta
3Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
Alireza Edraki
1RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
Raed Ibraheim
1RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
Kanae E. Sasaki
1RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
Lihua Julie Zhu
2Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
3Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
5Program in Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
Scot A. Wolfe
3Department of Molecular, Cell and Cancer Biology, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
4Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
Erik J. Sontheimer
1RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.
2Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, U.S.A.

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Posted August 04, 2017.
NmeCas9 is an intrinsically high-fidelity genome editing platform
Nadia Amrani, Xin D. Gao, Pengpeng Liu, Ankit Gupta, Alireza Edraki, Raed Ibraheim, Kanae E. Sasaki, Lihua Julie Zhu, Scot A. Wolfe, Erik J. Sontheimer
bioRxiv 172650; doi: https://doi.org/10.1101/172650
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