New Results
Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes
View ORCID ProfileDouglas M Ruderfer, Stephan Ripke, Andrew McQuillin, James Boocock, Eli A Stahl, Jennifer M Whitehead Pavlides, Niamh Mullins, Alexander W Charney, Anil P S Ori, Loes M Olde Loohuis, Enrico Domenici, Arianna Di Florio, Sergi Papiol, Janos L. Kalman, Rolf Adolfsson, Ingrid Agartz, Esben Agerbo, Huda Akil, Diego Albani, Margot Albus, Martin Alda, Madeline Alexander, Judith Allardyce, Ney Alliey-Rodriguez, Thomas D Als, Farooq Amin, Adebayo Anjorin, Maria J Arranz, Swapnil Awasthi, Silviu A Bacanu, Judith A Badner, Marie Baekvad-Hansen, Steven Bakker, Gavin Band, Jack D Barchas, Ines Barroso, Nicholas Bass, Michael Bauer, Bernhard T Baune, Martin Begemann, Celine Bellenguez, Richard A Belliveau Jr, Frank Bellivier, Stephan Bender, Judit Bene, Sarah E Bergen, Wade H Berrettini, Elizabeth Bevilacqua, Joanna M Biernacka, Tim B Bigdeli, Donald W Black, Hannah Blackburn, Jenefer M Blackwell, Douglas HR Blackwood, Carsten Bocker Pedersen, Michael Boehnke, Marco Boks, Anders D Borglum, Elvira Bramon, Gerome Breen, Matthew A Brown, Richard Bruggeman, Nancy G Buccola, Randy L Buckner, Monika Budde, Brendan Bulik-Sullivan, Suzannah J Bumpstead, William Bunney, Margit Burmeister, Joseph D Buxbaum, Jonas Bybjerg-Grauholm, William Byerley, Wiepke Cahn, Guiqing Cai, Murray J Cairns, Dominique Campion, Rita M Cantor, Vaughan J Carr, Noa Carrera, Juan P Casas, Miquel Casas, Stanley V Catts, Pablo Cervantes, Kimberley D Chambert, Raymond CK Chan, Eric YH Chen, Ronald YL Chen, Wei Cheng, Eric FC Cheung, Siow Ann Chong, Toni-Kim Clarke, C Robert Cloninger, David Cohen, Nadine Cohen, Jonathan R I Coleman, David A Collier, Paul Cormican, William Coryell, Nicholas Craddock, David W Craig, Benedicto Crespo-Facorro, James J Crowley, Cristiana Cruceanu, David Curtis, Piotr M Czerski, Anders M Dale, Mark J Daly, Udo Dannlowski, Ariel Darvasi, Michael Davidson, Kenneth L Davis, Christiaan A de Leeuw, Franziska Degenhardt, Jurgen Del Favero, Lynn E DeLisi, Panos Deloukas, Ditte Demontis, J Raymond DePaulo, Marta di Forti, Dimitris Dikeos, Timothy Dinan, Srdjan Djurovic, Amanda L Dobbyn, Peter Donnelly, Gary Donohoe, Elodie Drapeau, Serge Dronov, Jubao Duan, Frank Dudbridge, Audrey Duncanson, Howard Edenberg, Sarah Edkins, Hannelore Ehrenreich, Peter Eichhammer, Torbjorn Elvsashagen, Johan Eriksson, Valentina Escott-Price, Tonu Esko, Laurent Essioux, Bruno Etain, Chun Chieh Fan, Kai-How Farh, Martilias S Farrell, Matthew Flickinger, Tatiana M Foroud, Liz Forty, Josef Frank, Lude Franke, Christine Fraser, Robert Freedman, Colin Freeman, Nelson B Freimer, Joseph I Friedman, Menachem Fromer, Mark A Frye, Janice M Fullerton, Katrin Gade, Julie Garnham, Helena A Gaspar, Pablo V Gejman, Giulio Genovese, Lyudmila Georgieva, Claudia Giambartolomei, Eleni Giannoulatou, Ina Giegling, Michael Gill, Matthew Gillman, Marianne Giortz Pedersen, Paola Giusti-Rodriguez, Stephanie Godard, Fernando Goes, Jacqueline I Goldstein, Srihari Gopal, Scott D Gordon, Katherine Gordon-Smith, Jacob Gratten, Emma Gray, Elaine K Green, Melissa J Green, Tiffany A Greenwood, Maria Grigoroiu-Serbanescu, Jakob Grove, Weihua Guan, Hugh Gurling, Jose Guzman Parra, Rhian Gwilliam, Lieuwe de Haan, Jeremy Hall, Mei-Hua Hall, Christian Hammer, Naomi Hammond, Marian L Hamshere, Mark Hansen, Thomas Hansen, Vahram Haroutunian, Annette M Hartmann, Joanna Hauser, Martin Hautzinger, Urs Heilbronner, Garrett Hellenthal, Frans A Henskens, Stefan Herms, Maria Hipolito, Joel N Hirschhorn, Per Hoffmann, Mads V Hollegaard, David M Hougaard, Hailiang Huang, Laura Huckins, Christina M Hultman, Sarah E Hunt, Masashi Ikeda, Nakao Iwata, Conrad Iyegbe, Assen V Jablensky, Stephane Jamain, Janusz Jankowski, Alagurevathi Jayakumar, Inge Joa, Ian Jones, Lisa A Jones, Erik G Jonsson, Antonio Julia, Anders Jureus, Anna K Kahler, Rene S Kahn, Luba Kalaydjieva, Radhika Kandaswamy, Sena Karachanak-Yankova, Juha Karjalainen, Robert Karlsson, David Kavanagh, Matthew C Keller, Brian J Kelly, John Kelsoe, James L Kennedy, Andrey Khrunin, Yunjung Kim, George Kirov, Sarah Kittel-Schneider, Janis Klovins, Jo Knight, Sarah V Knott, James A Knowles, Manolis Kogevinas, Bettina Konte, Eugenia Kravariti, Vaidutis Kucinskas, Zita Ausrele Kucinskiene, Ralph Kupka, Hana Kuzelova-Ptackova, Mikael Landen, Cordelia Langford, Claudine Laurent, Jacob Lawrence, Stephen Lawrie, William B Lawson, Markus Leber, Marion Leboyer, Phil H Lee, Jimmy Lee Chee Keong, Sophie E Legge, Todd Lencz, Bernard Lerer, Douglas F Levinson, Shawn E Levy, Cathryn M Lewis, Jun Z Li, Miaoxin Li, Qingqin S Li, Tao Li, Kung-Yee Liang, Jennifer Liddle, Jeffrey Lieberman, Svetlana Limborska, Kuang Lin, Don H Linszen, Jolanta Lissowska, Chunyu Liu, Jianjun Liu, Jouko Lonnqvist, Carmel M Loughland, Jan Lubinski, Susanne Lucae, Milan Macek Jr, Donald J MacIntyre, Patrik KE Magnusson, Brion S Maher, Pamela B Mahon, Wolfgang Maier, Anil K Malhotra, Jacques Mallet, Ulrik F Malt, Hugh S Markus, Sara Marsal, Nicholas G Martin, Ignacio Mata, Christopher G Mathew, Manuel Mattheisen, Morten Mattingsdal, Fermin Mayoral, Owen T McCann, Robert W McCarley, Steven A McCarroll, Mark I McCarthy, Colm McDonald, Susan L McElroy, Peter McGuffin, Melvin G Mclnnis, Andrew M McIntosh, James D McKay, Francis J McMahon, Helena Medeiros, Sarah E Medland, Sandra Meier, Carin J Meijer, Bela Melegh, Ingrid Melle, Fan Meng, Raquelle I Mesholam-Gately, Andres Metspalu, Patricia T Michie, Lili Milani, Vihra Milanova, Philip B Mitchell, Younes Mokrab, Grant W Montgomery, Jennifer L Moran, Gunnar Morken, Derek W Morris, Ole Mors, Preben B Mortensen, Bryan J Mowry, Thomas W Mühleisen, Bertram Müller-Myhsok, Kieran C Murphy, Robin M Murray, Richard M Myers, Inez Myin-Germeys, Benjamin M Neale, Mari Nelis, Igor Nenadic, Deborah A Nertney, Gerald Nestadt, Kristin K Nicodemus, Caroline M Nievergelt, Liene Nikitina-Zake, Vishwajit Nimgaonkar, Laura Nisenbaum, Merete Nordentoft, Annelie Nordin, Markus M Nöthen, Evaristus A Nwulia, Eadbhard O’Callaghan, Claire O’Donovan, O’Dushlaine Colm, F Anthony O’Neill, Ketil J Oedegaard, Sang-Yun Oh, Ann Olincy, Line Olsen, Lilijana Oruc, Jim Van Os, Michael J Owen, Sara A Paciga, Colin N A Palmer, Aarno Palotie, Christos Pantelis, George N Papadimitriou, Elena Parkhomenko, Carlos Pato, Michele T Pato, Tiina Paunio, Richard Pearson, Psychosis Endophenotypes International Consortium, Diana O Perkins, Roy H Perlis, Amy Perry, Tune H Pers, Tracey L Petryshen, Andrea Pfennig, Marco Picchioni, Olli Pietilainen, Jonathan Pimm, Matti Pirinen, Robert Plomin, Andrew J Pocklington, Danielle Posthuma, James B Potash, Simon C Potter, John Powell, Alkes Price, Ann E Pulver, Shaun M Purcell, Digby Quested, Josep Antoni Ramos-Quiroga, Henrik B Rasmussen, Anna Rautanen, Radhi Ravindrarajah, Eline J Regeer, Abraham Reichenberg, Andreas Reif, Mark A Reimers, Marta Ribases, John P Rice, Alexander L Richards, Michelle Ricketts, Brien P Riley, Fabio Rivas, Margarita Rivera, Joshua L Roffman, Guy A Rouleau, Panos Roussos, Dan Rujescu, Veikko Salomaa, Cristina Sanchez-Mora, Alan R Sanders, Stephen J Sawcer, Ulrich Schall, Alan F Schatzberg, William A Scheftner, Peter R Schofield, Nicholas J Schork, Sibylle G Schwab, Edward M Scolnick, Laura J Scott, Rodney J Scott, Larry J Seidman, Alessandro Serretti, Pak C Sham, Cynthia Shannon Weickert, Tatyana Shehktman, Jianxin Shi, Paul D Shilling, Engilbert Sigurdsson, Jeremy M Silverman, Kang Sim, Claire Slaney, Petr Slominsky, Olav B Smeland, Jordan W Smoller, Hon-Cheong So, Janet L Sobell, Erik Soderman, Christine Soholm Hansen, Chris C A Spencer, Anne T Spijker, David St Clair, Hreinn Stefansson, Kari Stefansson, Stacy Steinberg, Elisabeth Stogmann, Eystein Stordal, Amy Strange, Richard E Straub, John S Strauss, Fabian Streit, Eric Strengman, Jana Strohmaier, T Scott Stroup, Zhan Su, Mythily Subramaniam, Jaana Suvisaari, Dragan M Svrakic, Jin P Szatkiewicz, Szabolcs Szelinger, Avazeh Tashakkori-Ghanbaria, Srinivas Thirumalai, Robert C Thompson, Thorgeir E Thorgeirsson, Draga Toncheva, Paul A Tooney, Sarah Tosato, Timothea Toulopoulou, Richard C Trembath, Jens Treutlein, Vassily Trubetskoy, Gustavo Turecki, Arne E Vaaler, Helmut Vedder, Eduard Vieta, John Vincent, Peter M Visscher, Ananth C Viswanathan, Damjan Vukcevic, John Waddington, Matthew Waller, Dermot Walsh, Muriel Walshe, James TR Walters, Dai Wang, Qiang Wang, Weiqing Wang, Yunpeng Wang, Stanley J Watson, Bradley T Webb, Thomas W Weickert, Daniel R Weinberger, Matthias Weisbrod, Mark Weiser, Thomas Werge, Paul Weston, Pamela Whittaker, Sara Widaa, Durk Wiersma, Dieter B Wildenauer, Nigel M Williams, Stephanie Williams, Stephanie H Witt, Aaron R Wolen, Emily HM Wong, Nicholas W Wood, Brandon K Wormley, Wellcome Trust Case-Control Consortium, Jing Qin Wu, Simon Xi, Wei Xu, Allan H Young, Clement C Zai, Peter Zandi, Peng Zhang, Xuebin Zheng, Fritz Zimprich, Sebastian Zollner, Aiden Corvin, Ayman H Fanous, Sven Cichon, Marcella Rietschel, Elliot S Gershon, Thomas G Schulze, Alfredo B Cuellar-Barboza, Andreas J Forstner, Peter A Holmans, John I Nurnberger, Ole A Andreassen, S Hong Lee, Michael C O’Donovan, Patrick F Sullivan, Roel A Ophoff, Naomi R Wray, View ORCID ProfilePamela Sklar, View ORCID ProfileKenneth S Kendler
doi: https://doi.org/10.1101/173435
Douglas M Ruderfer
1Division of Genetic Medicine, Departments of Medicine, Psychiatry, Biomedical Informatics, Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA
Stephan Ripke
2Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
3Department of Psychiatry and Psychotherapy, Charite - Universitatsmedizin, Berlin, Germany
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Andrew McQuillin
5Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK
James Boocock
6Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, California, USA
Eli A Stahl
7Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY USA
Jennifer M Whitehead Pavlides
8Queensland Brain Institute, The University of Queensland, Brisbane, Australia
Niamh Mullins
9MRC Social, Genetic and Developmental Psychiatry Centre, King’s College London, London, UK
Alexander W Charney
10Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Anil P S Ori
11Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA
Loes M Olde Loohuis
11Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA
Enrico Domenici
12Centre for Integrative Biology, University of Trento, Trento, Italy
Arianna Di Florio
13MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Sergi Papiol
14Institute of Psychiatric Phenomics and Genomics (IPPG), Medical Center of the University of Munich, Munich, Germany
15Department of Psychiatry and Psychotherapy, Ludwig Maximillian University, Munich, Germany
Janos L. Kalman
14Institute of Psychiatric Phenomics and Genomics (IPPG), Medical Center of the University of Munich, Munich, Germany
15Department of Psychiatry and Psychotherapy, Ludwig Maximillian University, Munich, Germany
Rolf Adolfsson
16Department of Clinical Sciences, Psychiatry, Umea University, Umea, Sweden
Ingrid Agartz
17Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Stockholm, Sweden
18Department of Psychiatry, Diakonhjemmet Hospital, Oslo, Norway
19NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Esben Agerbo
20Centre for Integrative Register-based Research, CIRRAU, Aarhus University, Aarhus, Denmark
21National Centre for Register-based Research, Aarhus University, Aarhus, Denmark
22The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
Huda Akil
23Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI USA
Diego Albani
24NEUROSCIENCE, Istituto Di Ricerche Farmacologiche Mario Negri, Milano, Italy
Margot Albus
25State Mental Hospital, Haar, Germany
Martin Alda
26Department of Psychiatry, Dalhousie University, Halifax, NS Canada
27National Institute of Mental Health, Klecany, Czech Republic
Madeline Alexander
28Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA
Judith Allardyce
29Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Ney Alliey-Rodriguez
30Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, USA
Thomas D Als
31Department of Biomedicine, Aarhus University, Aarhus, Denmark
22The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
32iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark
Farooq Amin
33Department of Psychiatry and Behavioral Sciences, Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, USA
34Department of Psychiatry and Behavioral Sciences, Emory University, Atlanta, Georgia, USA
Adebayo Anjorin
35Psychiatry, Berkshire Healthcare NHS Foundation Trust, Bracknell, UK
Maria J Arranz
36Fundacio de Docencia i Recerca Mutua de Terrassa, Universitat de Barcelona, Spain
37Institute of Psychiatry at King’s College London, London, UK
Swapnil Awasthi
3Department of Psychiatry and Psychotherapy, Charite - Universitatsmedizin, Berlin, Germany
Silviu A Bacanu
38Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA
Judith A Badner
39Psychiatry, Rush University Medical Center, Chicago, IL USA
Marie Baekvad-Hansen
40Statens Serum Institut, Copenhagen, Denmark
Steven Bakker
41Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
Gavin Band
42Wellcome Trust Centre for Human Genetics, Oxford, UK
Jack D Barchas
43Department of Psychiatry, Weill Cornell Medical College, New York, NY USA
Ines Barroso
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Nicholas Bass
45Division of Psychiatry, University College London, London, GB
Michael Bauer
46Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
Bernhard T Baune
47Discipline of Psychiatry, University of Adelaide, Adelaide, Australia
Martin Begemann
48Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Gottingen, Germany
Celine Bellenguez
42Wellcome Trust Centre for Human Genetics, Oxford, UK
Richard A Belliveau Jr
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Frank Bellivier
49Department of Psychiatry and Addiction Medicine, Assistance Publique - Hopitaux de Paris, Paris, France
50Paris Bipolar and TRD Expert Centres, FondaMental Foundation, Paris, France
51Psychiatry, Universite Paris Diderot, Paris, France
52UMR-S1144 Team 1: Biomarkers of relapse and therapeutic response in addiction and mood disorders, INSERM, Paris, France
Stephan Bender
53Child and Adolescent Psychiatry, University of Technology Dresden, Dresden, Germany
54Section for Experimental Psychopathology, General Psychiatry, Heidelberg, Germany
Judit Bene
55Department of Medical Genetics, University of Pecs, Pecs, Hungary
56Szentagothai Research Center, University of Pecs, Pecs, Hungary
Sarah E Bergen
57Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Wade H Berrettini
58Psychiatry, University of Pennsylvania, Philadelphia, PA USA
Elizabeth Bevilacqua
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Joanna M Biernacka
59Health Sciences Research, Mayo Clinic, Rochester, Minnesota USA
Tim B Bigdeli
38Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA
Donald W Black
60Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa, USA
Hannah Blackburn
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Jenefer M Blackwell
61Cambridge Institute for Medical Research, University of Cambridge School of Clinical Medicine, Cambridge, UK
62Telethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, subiaco, Western Australia, Australia
Douglas HR Blackwood
63Division of Psychiatry, University of Edinburgh, Edinburgh, UK
Carsten Bocker Pedersen
20Centre for Integrative Register-based Research, CIRRAU, Aarhus University, Aarhus, Denmark
22The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
21National Centre for Register-based Research, Aarhus University, Aarhus, Denmark
Michael Boehnke
64Center for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, Michigan USA
Marco Boks
41Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
Anders D Borglum
32iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark
65Department of Biomedicine, Aarhus University, Aarhus C, Denmark
22The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
Elvira Bramon
66Institute of Cognitive Neuroscience, University College London, London, UK
37Institute of Psychiatry at King’s College London, London, UK
67Mental Health Sciences Unit, University College London, London, UK
Gerome Breen
9MRC Social, Genetic and Developmental Psychiatry Centre, King’s College London, London, UK
68NIHR BRC for Mental Health, King’s College London, London, UK
Matthew A Brown
69Diamantina Institute of Cancer, Immunology and Metabolic Medicine, Princess Alexandra Hospital, University of Queensland, Brisbane, Queensland, Australia
Richard Bruggeman
70University Medical Center Groningen, Department of Psychiatry, University of Groningen, RB, The Netherlands
Nancy G Buccola
71School of Nursing, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA
Randy L Buckner
72Athinoula A. Martinos Center, Massachusetts General Hospital, Boston, Massachusetts, USA
73Center for Brain Science, Harvard University, Cambridge, Massachusetts, USA
74Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
Monika Budde
14Institute of Psychiatric Phenomics and Genomics (IPPG), Medical Center of the University of Munich, Munich, Germany
Brendan Bulik-Sullivan
2Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Suzannah J Bumpstead
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
William Bunney
75Department of Psychiatry and Human Behavior, University of California, Irvine, Irvine, California USA
Margit Burmeister
76Molecular & Behavioral Neuroscience Institute and Department of Computational Medicine & Bioinformatics, University of Michigan, Ann Arbor, Michigan USA
Joseph D Buxbaum
77Department of Human Genetics, Icahn School of Medicine at Mount Sinai, New York, New York, USA
78Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA
10Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
79Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Jonas Bybjerg-Grauholm
80Neonatal Genetik, Statens Serum Institut, Copenhagen, Denmark
William Byerley
81Department of Psychiatry, University of California San Francisco, San Francisco, California, USA
Wiepke Cahn
41Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
Guiqing Cai
77Department of Human Genetics, Icahn School of Medicine at Mount Sinai, New York, New York, USA
10Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Murray J Cairns
82Priority Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, Australia
83Schizophrenia Research Institute, Sydney, Australia
84School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia
Dominique Campion
85Centre Hospitalier du Rouvray and INSERM U 1079Faculty of Medicine, Rouen, France
Rita M Cantor
6Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, California, USA
Vaughan J Carr
83Schizophrenia Research Institute, Sydney, Australia
86School of Psychiatry, University of New South Wales, Sydney, Australia
Noa Carrera
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
Juan P Casas
88Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
89Department of Epidemiology and Public Health, University College London, London, UK
Miquel Casas
90Department of Psychiatry and Forensic Medicine, Universitat Autonoma de Barcelona, Barcelona, Spain
91Department of Psychiatry, Hospital Universitari Vall ďHebron, Barcelona, Spain
92Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain
93Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall ďHebron Research Institut (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain
Stanley V Catts
94Royal Brisbane and Women’s Hospital, University of Queensland, Brisbane, Australia
83Schizophrenia Research Institute, Sydney, Australia
Pablo Cervantes
95Department of Psychiatry, Mood Disorders Program, McGill University Health Center, Montreal, QC Canada
Kimberley D Chambert
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Raymond CK Chan
96Institute of Psychology, Chinese Academy of Science, Beijing, China
Eric YH Chen
97Department of Psychiatry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
98State Key Laboratory for Brain and Cognitive Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Ronald YL Chen
97Department of Psychiatry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Wei Cheng
99Department of Computer Science, University of North Carolina, Chapel Hill, North Carolina, USA
Eric FC Cheung
100Castle Peak Hospital, Hong Kong, China
Siow Ann Chong
101Institute of Mental Health, Singapore, Singapore
Toni-Kim Clarke
63Division of Psychiatry, University of Edinburgh, Edinburgh, UK
C Robert Cloninger
102Department of Psychiatry, Washington University, St. Louis, Missouri, USA
David Cohen
103Department of Child and Adolescent Psychiatry, Assistance Publique Hospitaux de Paris, Pierre and Marie Curie Faculty of Medicine and Institute for Intelligent Systems and Robotics, Paris, France
Nadine Cohen
104Blue Note Biosciences, Princeton, New Jersey, USA
Jonathan R I Coleman
9MRC Social, Genetic and Developmental Psychiatry Centre, King’s College London, London, UK
68NIHR BRC for Mental Health, King’s College London, London, UK
David A Collier
105Eli Lilly and Company Limited, Erl Wood Manor, Sunninghill Road, Windlesham, Surrey, UK
106Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, London, UK
Paul Cormican
107Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Ireland
William Coryell
108University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
Nicholas Craddock
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
109National Centre for Mental Health, Cardiff University, Cardiff, UK
David W Craig
110Translational Genomics, USAC, Phoenix, Arizona, USA
Benedicto Crespo-Facorro
111Centro Investigacion Biomedica en Red Salud Mental, Madrid, Spain
112University Hospital Marques de Valdecilla, Instituto de Formacion e Investigacion Marques de Valdecilla, University of Cantabria, Santander, Spain
James J Crowley
113Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA
Cristiana Cruceanu
114Department of Translational Research in Psychiatry, Max Planck Institute of Psychiatry, Munich, Germany
David Curtis
115Centre for Psychiatry, Queen Mary University of London, London, UK
116UCL Genetics Institute, University College London, London, UK
Piotr M Czerski
117Department of Psychiatry, Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland
Anders M Dale
118Neurosciences, Radiology, Psychiatry, Cognitive Science, University of California San Diego, La Jolla, California USA
Mark J Daly
2Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
119Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Udo Dannlowski
120Department of Psychiatry, University of Munster, Munster, Germany
Ariel Darvasi
121Department of Genetics, The Hebrew University of Jer USA lem, JerUSAlem, Israel
Michael Davidson
122Sheba Medical Center, Tel Hashomer, Israel
Kenneth L Davis
10Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Christiaan A de Leeuw
123Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
Franziska Degenhardt
124Life&Brain Center, Department of Genomics, University of Bonn, Bonn, Germany
125Institute of Human Genetics, University of Bonn, Bonn, Germany
125Institute of Human Genetics, University of Bonn, Bonn, Germany
124Life&Brain Center, Department of Genomics, University of Bonn, Bonn, Germany
Jurgen Del Favero
126Applied Molecular Genomics Unit, VIB Department of Molecular Genetics, University of Antwerp, Antwerp, Belgium
Lynn E DeLisi
127Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
128VA Boston Health Care System, Brockton, Massachusetts, USA
Panos Deloukas
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Ditte Demontis
32iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark
31Department of Biomedicine, Aarhus University, Aarhus, Denmark
22The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
J Raymond DePaulo
129Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Marta di Forti
130King’s College London, London, UK
Dimitris Dikeos
131First Department of Psychiatry, University of Athens Medical School, Athens, Greece
Timothy Dinan
132Department of Psychiatry, University College Cork, Co. Cork, Ireland
Srdjan Djurovic
133Department of Medical Genetics, Oslo University Hospital, Oslo, Norway
19NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Amanda L Dobbyn
7Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY USA
134Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Peter Donnelly
135Department of Statistics, University of Oxford, Oxford, UK
42Wellcome Trust Centre for Human Genetics, Oxford, UK
Gary Donohoe
136Cognitive Genetics and Therapy Group, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Co. Galway, Ireland
107Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Ireland
Elodie Drapeau
10Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Serge Dronov
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Jubao Duan
30Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, USA
137Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, Evanston, Illinois, USA
Frank Dudbridge
138Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK
Audrey Duncanson
139Molecular and Physiological Sciences, The Wellcome Trust, London, UK
Howard Edenberg
140Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana USA
Sarah Edkins
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Hannelore Ehrenreich
48Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Gottingen, Germany
Peter Eichhammer
141Department of Psychiatry, University of Regensburg, Regensburg, Germany
Torbjorn Elvsashagen
142Department of Neurology, Oslo University Hospital, Oslo, Norway
19NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Johan Eriksson
143Department of General Practice, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland
144Folkhalsan Research Center, Helsinki, Finland, Biomedicum Helsinki 1, Haartmaninkatu 8, Helsinki, Finland
145National Institute for Health and Welfare, Helsinki, Finland
Valentina Escott-Price
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
Tonu Esko
146Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
147Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts, USA
148Estonian Genome Center, University of Tartu, Tartu, Estonia
119Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Laurent Essioux
149Translational Technologies and Bioinformatics, Pharma Research and Early Development, F.Hoffman-La Roche, Basel, Switzerland
Bruno Etain
150Centre for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, London, UK
49Department of Psychiatry and Addiction Medicine, Assistance Publique - Hopitaux de Paris, Paris, France
51Psychiatry, Universite Paris Diderot, Paris, France
52UMR-S1144 Team 1: Biomarkers of relapse and therapeutic response in addiction and mood disorders, INSERM, Paris, France
Chun Chieh Fan
151Cognitive Science, University of California San Diego, La Jolla, California USA
Kai-How Farh
2Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
Martilias S Farrell
113Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA
Matthew Flickinger
64Center for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, Michigan USA
Tatiana M Foroud
152Department of Medical & Molecular Genetics, Indiana University, Indianapolis, Indiana USA
Liz Forty
29Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Josef Frank
153Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Mannheim, Germany
Lude Franke
154Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands
Christine Fraser
29Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Robert Freedman
155Department of Psychiatry, University of Colorado Denver, Aurora, Colorado, USA
Colin Freeman
42Wellcome Trust Centre for Human Genetics, Oxford, UK
Nelson B Freimer
11Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA
Joseph I Friedman
10Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Menachem Fromer
2Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
134Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
156Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Mark A Frye
157Department of Psychiatry & Psychology, Mayo Clinic, Rochester, Minnesota USA
Janice M Fullerton
158Neuroscience Research Australia, Sydney, Australia
159School of Medical Sciences, University of New South Wales, Sydney, Australia
Katrin Gade
160Department of Psychiatry and Psychotherapy, University Medical Center Gottingen, Gottingen, Germany
14Institute of Psychiatric Phenomics and Genomics (IPPG), Medical Center of the University of Munich, Munich, Germany
Julie Garnham
26Department of Psychiatry, Dalhousie University, Halifax, NS Canada
Helena A Gaspar
9MRC Social, Genetic and Developmental Psychiatry Centre, King’s College London, London, UK
Pablo V Gejman
30Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, USA
137Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, Evanston, Illinois, USA
Giulio Genovese
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Lyudmila Georgieva
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
Claudia Giambartolomei
6Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, California, USA
Eleni Giannoulatou
42Wellcome Trust Centre for Human Genetics, Oxford, UK
Ina Giegling
161Department of Psychiatry, University of Halle, Halle, Germany
162Department of Psychiatry, University of Munich, Munich, Germany
Michael Gill
163Neuropsychiatric Genetics Research Group, Dept of Psychiatry and Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland
Matthew Gillman
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Marianne Giortz Pedersen
164Department of Economics and Business Economics, National Centre for Register-based Research, Aarhus University, Aarhus, Denmark
Paola Giusti-Rodriguez
113Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA
Stephanie Godard
165Departments of Psychiatry and Human and Molecular Genetics, INSERM, Institut de Myologie, Hopital de la Pitie-Salpetriere, Paris, France
Fernando Goes
129Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Jacqueline I Goldstein
2Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
119Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Srihari Gopal
166Neuroscience Therapeutic Area, Janssen Research and Development, Raritan, New Jersey, USA
Scott D Gordon
167Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia
Katherine Gordon-Smith
168Department of Psychological Medicine, University of Worcester, Worcester, UK
Jacob Gratten
8Queensland Brain Institute, The University of Queensland, Brisbane, Australia
Emma Gray
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Elaine K Green
169School of Biomedical and Healthcare Sciences, Plymouth University Peninsula Schools of Medicine and Dentistry, Plymouth, UK
Melissa J Green
86School of Psychiatry, University of New South Wales, Sydney, Australia
Tiffany A Greenwood
170Department of Psychiatry, University of California San Diego, La Jolla, California USA
Maria Grigoroiu-Serbanescu
171Biometric Psychiatric Genetics Research Unit, Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, Romania
Jakob Grove
172Bioinformatics Research Centre (BiRC), Aarhus University, Aarhus, Denmark
31Department of Biomedicine, Aarhus University, Aarhus, Denmark
22The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
32iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark
Weihua Guan
173Biostatistics, University of Minnesota System, Minneapolis, MN USA
Hugh Gurling
5Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK
Jose Guzman Parra
174Mental Health Department, University Regional Hospital. Biomedicine Institute (IBIMA), Malaga, Spain
Rhian Gwilliam
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Lieuwe de Haan
175Academic Medical Centre University of Amsterdam, Department of Psychiatry, Amsterdam, The Netherlands
Jeremy Hall
63Division of Psychiatry, University of Edinburgh, Edinburgh, UK
Mei-Hua Hall
176Mclean Hospital, Harvard Medical School, 115 Mill St, Belmont Massachusetts, USA
Christian Hammer
48Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Gottingen, Germany
Naomi Hammond
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Marian L Hamshere
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
Mark Hansen
177Illumina, La Jolla, California, California, USA
Thomas Hansen
178Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services Copenhagen, Denmark
22The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
Vahram Haroutunian
10Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
79Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA
179J.J. Peters VA Medical Center, Bronx, New York, New York, USA
Annette M Hartmann
161Department of Psychiatry, University of Halle, Halle, Germany
Joanna Hauser
117Department of Psychiatry, Laboratory of Psychiatric Genetics, Poznan University of Medical Sciences, Poznan, Poland
Martin Hautzinger
180Department of Psychology, Eberhard Karls Universitat Tobingen, Tubingen, Germany
Urs Heilbronner
14Institute of Psychiatric Phenomics and Genomics (IPPG), Medical Center of the University of Munich, Munich, Germany
Garrett Hellenthal
42Wellcome Trust Centre for Human Genetics, Oxford, UK
Frans A Henskens
181Priority Centre for Health Behaviour, University of Newcastle, Newcastle, Australia
83Schizophrenia Research Institute, Sydney, Australia
182School of Electrical Engineering and Computer Science, University of Newcastle, Newcastle, Australia
Stefan Herms
183Department of Biomedicine, University of Basel, Basel, Switzerland
124Life&Brain Center, Department of Genomics, University of Bonn, Bonn, Germany
125Institute of Human Genetics, University of Bonn, Bonn, Germany
Maria Hipolito
184Department of Psychiatry and Behavioral Sciences, Howard University Hospital, Washington, DC USA
Joel N Hirschhorn
146Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
147Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts, USA
119Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Per Hoffmann
124Life&Brain Center, Department of Genomics, University of Bonn, Bonn, Germany
183Department of Biomedicine, University of Basel, Basel, Switzerland
125Institute of Human Genetics, University of Bonn, Bonn, Germany
185Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland
Mads V Hollegaard
186Section of Neonatal Screening and Hormones, Department of Clinical Biochemistry, Immunology and Genetics, Statens Serum Institut, Copenhagen, Denmark
David M Hougaard
187Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark
186Section of Neonatal Screening and Hormones, Department of Clinical Biochemistry, Immunology and Genetics, Statens Serum Institut, Copenhagen, Denmark
Hailiang Huang
2Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
119Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Laura Huckins
7Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY USA
134Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Christina M Hultman
57Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Sarah E Hunt
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Masashi Ikeda
188Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
Nakao Iwata
188Department of Psychiatry, Fujita Health University School of Medicine, Toyoake, Aichi, Japan
Conrad Iyegbe
37Institute of Psychiatry at King’s College London, London, UK
Assen V Jablensky
189Centre for Clinical Research in Neuropsychiatry, School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Medical Research Foundation Building, Perth, Australia
83Schizophrenia Research Institute, Sydney, Australia
190School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Perth, Australia
191The Perkins Institute for Medical Research,The University of Western Australia, Perth, Australia
Stephane Jamain
192Faculte de Medecine, Universite Paris Est, Creteil, France
193Psychiatrie Translationnelle, Inserm U955, Creteil, France
Janusz Jankowski
194Peninsula School of Medicine and Dentistry, Plymouth University, Plymouth, UK
Alagurevathi Jayakumar
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Inge Joa
195Regional Centre for Clinical Research in Psychosis, Department of Psychiatry, Stavanger University Hospital, Stavanger, Norway
Ian Jones
29Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
Lisa A Jones
168Department of Psychological Medicine, University of Worcester, Worcester, UK
Erik G Jonsson
17Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Stockholm, Sweden
19NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Antonio Julia
196Rheumatology Research Group, Vall ďHebron Research Institute, Barcelona, Spain
Anders Jureus
57Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Anna K Kahler
57Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Rene S Kahn
41Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
10Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Luba Kalaydjieva
197Centre for Medical Research, The University of Western Australia, Perth, Western Australia, Australia
198Western Australian Institute for Medical Research, The University of Western Australia, Perth, Western Australia, Australia
Radhika Kandaswamy
9MRC Social, Genetic and Developmental Psychiatry Centre, King’s College London, London, UK
Sena Karachanak-Yankova
199Department of Medical Genetics, Medical University, Sofia, Bulgaria
Juha Karjalainen
154Department of Genetics, University of Groningen, University Medical Centre Groningen, Groningen, The Netherlands
Robert Karlsson
57Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
David Kavanagh
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
Matthew C Keller
200Department of Psychology, University of Colorado Boulder, Boulder, Colorado, USA
Brian J Kelly
82Priority Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, Australia
John Kelsoe
170Department of Psychiatry, University of California San Diego, La Jolla, California USA
James L Kennedy
201Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
202Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
203Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
Andrey Khrunin
204Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia
Yunjung Kim
113Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA
George Kirov
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
Sarah Kittel-Schneider
205Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
Janis Klovins
206Latvian Biomedical Research and Study Centre, Riga, Latvia
Jo Knight
201Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
202Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
203Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada
Sarah V Knott
168Department of Psychological Medicine, University of Worcester, Worcester, UK
James A Knowles
207Cell Biology, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY USA
208Department of Psychiatry and Zilkha Neurogenetics Institute, Keck School of Medicine at University of Southern California, Los Angeles, California, USA
209Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY USA
Manolis Kogevinas
210Center for Research in Environmental Epidemiology (CREAL), Barcelona, Spain
Bettina Konte
161Department of Psychiatry, University of Halle, Halle, Germany
Eugenia Kravariti
130King’s College London, London, UK
Vaidutis Kucinskas
211Faculty of Medicine, Vilnius University, Vilnius, Lithuania
Zita Ausrele Kucinskiene
211Faculty of Medicine, Vilnius University, Vilnius, Lithuania
Ralph Kupka
41Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
212Psychiatry, GGZ inGeest, Amsterdam, The Netherlands
213Psychiatry, VU medisch centrum, Amsterdam, The Netherlands
Hana Kuzelova-Ptackova
214Department of Biology and Medical Genetics, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic
Mikael Landen
57Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
215Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden
Cordelia Langford
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Claudine Laurent
216Department of Child and Adolescent Psychiatry, Pierre and Marie Curie Faculty of Medicine, Paris, France
28Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA
Jacob Lawrence
217Psychiatry, North East London NHS Foundation Trust, Ilford, UK
Stephen Lawrie
63Division of Psychiatry, University of Edinburgh, Edinburgh, UK
William B Lawson
184Department of Psychiatry and Behavioral Sciences, Howard University Hospital, Washington, DC USA
Markus Leber
218Clinic for Psychiatry and Psychotherapy, University Hospital Cologne, Cologne, Germany
Marion Leboyer
49Department of Psychiatry and Addiction Medicine, Assistance Publique - Hopitaux de Paris, Paris, France
192Faculte de Medecine, Universite Paris Est, Creteil, France
219INSERM, Paris, France
Phil H Lee
2Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
156Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Jimmy Lee Chee Keong
220Duke-NUSA Graduate Medical School, Singapore, Singapore
101Institute of Mental Health, Singapore, Singapore
Sophie E Legge
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
Todd Lencz
221Hofstra Northwell School of Medicine, Hempstead, New York, USA
222The Feinstein Institute for Medical Research, Manhasset, New York, USA
223The Hofstra NS-LIJ School of Medicine, Hempstead, New York, USA
Bernard Lerer
224Department of Psychiatry, Hadassah-Hebrew University Medical Center, Jerusalem, Israel
Douglas F Levinson
28Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA
Shawn E Levy
225HudsonAlpha Institute for Biotechnology, Huntsville, AL USA
Cathryn M Lewis
226Department of Medical & Molecular Genetics, King’s College London, London, UK
37Institute of Psychiatry at King’s College London, London, UK
9MRC Social, Genetic and Developmental Psychiatry Centre, King’s College London, London, UK
Jun Z Li
227Department of Human Genetics, University of Michigan, Ann Arbor, MI USA
Miaoxin Li
228Centre for Genomic Sciences, The University of Hong Kong, Hong Kong, China
97Department of Psychiatry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
98State Key Laboratory for Brain and Cognitive Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Qingqin S Li
166Neuroscience Therapeutic Area, Janssen Research and Development, Raritan, New Jersey, USA
166Neuroscience Therapeutic Area, Janssen Research and Development, Raritan, New Jersey, USA
Tao Li
229Mental Health Centre and Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan, China
Kung-Yee Liang
230Department of Biostatistics, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
Jennifer Liddle
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Jeffrey Lieberman
231Department of Psychiatry, Columbia University, New York, New York, USA
Svetlana Limborska
204Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia
Kuang Lin
37Institute of Psychiatry at King’s College London, London, UK
Don H Linszen
232Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Jolanta Lissowska
233Cancer Epidemiology and Prevention, M. Sklodowska-Curie Cancer Center and Institute of Oncology, Warsaw, Poland
Chunyu Liu
234Psychiatry, University of Illinois at Chicago College of Medicine, Chicago, IL USA
Jianjun Liu
235Human Genetics, Genome Institute of Singapore, A∗STAR, Singapore, Singapore
236Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore
Jouko Lonnqvist
237Department of Mental Health and substance Abuse Services; National Institute for Health and Welfare, Helsinki, Finland
Carmel M Loughland
82Priority Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, Australia
83Schizophrenia Research Institute, Sydney, Australia
Jan Lubinski
238Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University in Szczecin, Szczecin, Poland
Susanne Lucae
239Max Planck Institute of Psychiatry, Munich, Germany
Milan Macek Jr
214Department of Biology and Medical Genetics, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic
Donald J MacIntyre
240Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK
241Mental Health, NHS 24, Glasgow, UK
Patrik KE Magnusson
57Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Brion S Maher
242Department of Mental Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA
Pamela B Mahon
129Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
243Psychiatry, Brigham and Women’s Hospital, Boston, MA USA
Wolfgang Maier
244Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany
Anil K Malhotra
222The Feinstein Institute for Medical Research, Manhasset, New York, USA
223The Hofstra NS-LIJ School of Medicine, Hempstead, New York, USA
245The Zucker Hillside Hospital, Glen Oaks, New York, USA
Jacques Mallet
246Centre National de la Recherche Scientifique, Laboratoire de Genetique Moleculaire de la Neurotransmission et des Processus Neurodegeneratifs, Hopital de la Pitie Salpetriere, Paris, France
Ulrik F Malt
247Research and Education, Division of Clinical Neuroscience, Oslo Universitetssykehus, Oslo, Norway
Hugh S Markus
248Clinical Neurosciences, St George’s University of London, London, UK
Sara Marsal
196Rheumatology Research Group, Vall ďHebron Research Institute, Barcelona, Spain
Nicholas G Martin
167Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia
249School of Psychology, The University of Queensland, Brisbane, Australia
Ignacio Mata
111Centro Investigacion Biomedica en Red Salud Mental, Madrid, Spain
112University Hospital Marques de Valdecilla, Instituto de Formacion e Investigacion Marques de Valdecilla, University of Cantabria, Santander, Spain
Christopher G Mathew
250Department of Medical and Molecular Genetics, School of Medicine, King’s College London, Guy’s Hospital, London, UK
Manuel Mattheisen
32iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark
31Department of Biomedicine, Aarhus University, Aarhus, Denmark
17Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Stockholm, Sweden
251Department of Genomics Mathematics, University of Bonn, D-53127 Bonn, Germany
32iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark
252Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden
22The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
Morten Mattingsdal
19NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
253Research Unit, Sorlandet Hospital, Kristiansand, Norway
Fermin Mayoral
174Mental Health Department, University Regional Hospital. Biomedicine Institute (IBIMA), Malaga, Spain
Owen T McCann
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Robert W McCarley
127Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
128VA Boston Health Care System, Brockton, Massachusetts, USA
Steven A McCarroll
146Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Mark I McCarthy
254Oxford Centre for Diabetes, Endocrinology and Metabolism, Churchill Hospital, Oxford, UK
Colm McDonald
255Department of Psychiatry, National University of Ireland Galway, Co. Galway, Ireland
Susan L McElroy
256Research Institute, Lindner Center of HOPE, Mason, OH USA
Peter McGuffin
9MRC Social, Genetic and Developmental Psychiatry Centre, King’s College London, London, UK
Melvin G Mclnnis
257Department of Psychiatry, University of Michigan, Ann Arbor, MI USA
Andrew M McIntosh
258Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK
63Division of Psychiatry, University of Edinburgh, Edinburgh, UK
James D McKay
259Genetic Cancer Susceptibility Group, International Agency for Research on Cancer, Lyon, France
Francis J McMahon
260Human Genetics Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD USA
Helena Medeiros
209Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY USA
Sarah E Medland
167Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, Australia
Sandra Meier
153Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Mannheim, Germany
Carin J Meijer
175Academic Medical Centre University of Amsterdam, Department of Psychiatry, Amsterdam, The Netherlands
Bela Melegh
55Department of Medical Genetics, University of Pecs, Pecs, Hungary
56Szentagothai Research Center, University of Pecs, Pecs, Hungary
Ingrid Melle
261Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
19NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Fan Meng
257Department of Psychiatry, University of Michigan, Ann Arbor, MI USA
23Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI USA
Raquelle I Mesholam-Gately
127Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
262Massachusetts Mental Health Center Public Psychiatry Division of the Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
Andres Metspalu
148Estonian Genome Center, University of Tartu, Tartu, Estonia
263Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia
Patricia T Michie
83Schizophrenia Research Institute, Sydney, Australia
264School of Psychology, University of Newcastle, Newcastle, Australia
Lili Milani
148Estonian Genome Center, University of Tartu, Tartu, Estonia
Vihra Milanova
265First Psychiatric Clinic, Medical University, Sofia, Bulgaria
Philip B Mitchell
86School of Psychiatry, University of New South Wales, Sydney, Australia
Younes Mokrab
105Eli Lilly and Company Limited, Erl Wood Manor, Sunninghill Road, Windlesham, Surrey, UK
Grant W Montgomery
266Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia
Jennifer L Moran
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Gunnar Morken
267Mental Health, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology - NTNU, Trondheim, Norway
268Psychiatry, St Olavs University Hospital, Trondheim, Norway
Derek W Morris
269Discipline of Biochemistry, Neuroimaging and Cognitive Genomics (NICOG) Centre, National University of Ireland, Galway, Galway, Ireland
107Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Ireland
Ole Mors
32iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, Denmark
22The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
Preben B Mortensen
20Centre for Integrative Register-based Research, CIRRAU, Aarhus University, Aarhus, Denmark
21National Centre for Register-based Research, Aarhus University, Aarhus, Denmark
22The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
Bryan J Mowry
8Queensland Brain Institute, The University of Queensland, Brisbane, Australia
270Queensland Centre for Mental Health Research, University of Queensland, Brisbane, Australia
Thomas W Mühleisen
183Department of Biomedicine, University of Basel, Basel, Switzerland
271Institute of Neuroscience and Medicine (INM-1), Research Center Juelich, Juelich, Germany
Bertram Müller-Myhsok
272Institute of Translational Medicine, University of Liverpool, Liverpool, UK
239Max Planck Institute of Psychiatry, Munich, Germany
273Munich Cluster for Systems Neurology (SyNergy), Munich, Germany
Kieran C Murphy
274Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland
Robin M Murray
130King’s College London, London, UK
Richard M Myers
225HudsonAlpha Institute for Biotechnology, Huntsville, AL USA
Inez Myin-Germeys
275Maastricht University Medical Centre, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht, The Netherlands
Benjamin M Neale
2Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
119Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
156Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Mari Nelis
148Estonian Genome Center, University of Tartu, Tartu, Estonia
Igor Nenadic
276Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany
Deborah A Nertney
270Queensland Centre for Mental Health Research, University of Queensland, Brisbane, Australia
Gerald Nestadt
129Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Kristin K Nicodemus
277Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
Caroline M Nievergelt
170Department of Psychiatry, University of California San Diego, La Jolla, California USA
278Research/Psychiatry, Veterans Affairs San Diego Healthcare System, San Diego, California USA
Liene Nikitina-Zake
206Latvian Biomedical Research and Study Centre, Riga, Latvia
Vishwajit Nimgaonkar
279Psychiatry and Human Genetics, University of Pittsburgh, Pittsburgh, PA USA
Laura Nisenbaum
280Eli Lilly and Company, Lilly Corporate Center, Indianapolis, Indiana, USA
Merete Nordentoft
281Mental Health Centre Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark
Annelie Nordin
16Department of Clinical Sciences, Psychiatry, Umea University, Umea, Sweden
Markus M Nöthen
124Life&Brain Center, Department of Genomics, University of Bonn, Bonn, Germany
125Institute of Human Genetics, University of Bonn, Bonn, Germany
Evaristus A Nwulia
184Department of Psychiatry and Behavioral Sciences, Howard University Hospital, Washington, DC USA
Eadbhard O’Callaghan
282DETECT Early Intervention Service for Psychosis, Blackrock, Co. Dublin, Ireland
Claire O’Donovan
26Department of Psychiatry, Dalhousie University, Halifax, NS Canada
O’Dushlaine Colm
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
F Anthony O’Neill
283Centre for Public Health, Institute of Clinical Sciences, Queen’s University Belfast, Belfast, UK
Ketil J Oedegaard
284Division of Psychiatry, Haukeland Universitetssjukehus, Bergen, Norway
285Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway
Sang-Yun Oh
286Lawrence Berkeley National Laboratory, University of California at Berkeley, Berkeley, California, USA
Ann Olincy
155Department of Psychiatry, University of Colorado Denver, Aurora, Colorado, USA
Line Olsen
178Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services Copenhagen, Denmark
22The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
Lilijana Oruc
287Department of Clinical Psychiatry, Psychiatry Clinic, Clinical Center University of Sarajevo, Sarajevo, Bosnia
Jim Van Os
37Institute of Psychiatry at King’s College London, London, UK
275Maastricht University Medical Centre, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht, The Netherlands
Michael J Owen
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
109National Centre for Mental Health, Cardiff University, Cardiff, UK
Sara A Paciga
288Human Genetics and Computational Biomedicine, Pfizer Global Research and Development, Groton, Connecticut, USA
Colin N A Palmer
289Biomedical Research Centre, Ninewells Hospital and Medical School, Dundee, UK
Aarno Palotie
290Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland
156Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Christos Pantelis
291Melbourne Neuropsychiatry Centre, University of Melbourne & Melbourne Health, Melbourne, Australia
83Schizophrenia Research Institute, Sydney, Australia
George N Papadimitriou
131First Department of Psychiatry, University of Athens Medical School, Athens, Greece
Elena Parkhomenko
10Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Carlos Pato
292College of Medicine Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY USA
209Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY USA
Michele T Pato
209Institute for Genomic Health, SUNY Downstate Medical Center College of Medicine, Brooklyn, NY USA
Tiina Paunio
293Department of Psychiatry, University of Helsinki, Helsinki, Finland
294Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland
Richard Pearson
42Wellcome Trust Centre for Human Genetics, Oxford, UK
295PEIC
Diana O Perkins
296Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina USA
Roy H Perlis
297Division of Clinical Research, Massachusetts General Hospital, Boston, MA USA
127Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
Amy Perry
168Department of Psychological Medicine, University of Worcester, Worcester, UK
Tune H Pers
298Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Denmark
147Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children’s Hospital, Boston, Massachusetts, USA
119Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Tracey L Petryshen
299Center for Human Genetic Research and Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
127Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Andrea Pfennig
46Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Dresden, Germany
Marco Picchioni
130King’s College London, London, UK
Olli Pietilainen
290Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland
294Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland
Jonathan Pimm
5Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK
Matti Pirinen
42Wellcome Trust Centre for Human Genetics, Oxford, UK
Robert Plomin
106Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, London, UK
Andrew J Pocklington
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
Danielle Posthuma
300Department of Child and Adolescent Psychiatry, Erasmus University Medical Centre, Rotterdam, The Netherlands
301Department of Complex Trait Genetics, Neuroscience Campus Amsterdam, VU University Medical Center Amsterdam, Amsterdam, The Netherlands
302Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands
James B Potash
129Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Simon C Potter
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
John Powell
37Institute of Psychiatry at King’s College London, London, UK
Alkes Price
303Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
119Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Ann E Pulver
129Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Shaun M Purcell
134Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
243Psychiatry, Brigham and Women’s Hospital, Boston, MA USA
Digby Quested
304Department of Psychiatry, University of Oxford, Oxford, UK
Josep Antoni Ramos-Quiroga
90Department of Psychiatry and Forensic Medicine, Universitat Autonoma de Barcelona, Barcelona, Spain
91Department of Psychiatry, Hospital Universitari Vall ďHebron, Barcelona, Spain
92Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain
93Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall ďHebron Research Institut (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain
Henrik B Rasmussen
178Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services Copenhagen, Denmark
22The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
Anna Rautanen
42Wellcome Trust Centre for Human Genetics, Oxford, UK
Radhi Ravindrarajah
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Eline J Regeer
305Outpatient Clinic for Bipolar Disorder, Altrecht, Utrecht, The Netherlands
Abraham Reichenberg
10Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
79Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Andreas Reif
205Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
Mark A Reimers
306Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, USA
Marta Ribases
91Department of Psychiatry, Hospital Universitari Vall ďHebron, Barcelona, Spain
92Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain
93Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall ďHebron Research Institut (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain
John P Rice
102Department of Psychiatry, Washington University, St. Louis, Missouri, USA
Alexander L Richards
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
109National Centre for Mental Health, Cardiff University, Cardiff, UK
Michelle Ricketts
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Brien P Riley
307Virginia Institute for Psychiatric and Behavioral Genetics, Departments of Psychiatry and Human and Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia, USA
Fabio Rivas
174Mental Health Department, University Regional Hospital. Biomedicine Institute (IBIMA), Malaga, Spain
Margarita Rivera
308Department of Biochemistry and Molecular Biology II, Institute of Neurosciences, Center for Biomedical Research, University of Granada, Granada, Spain
9MRC Social, Genetic and Developmental Psychiatry Centre, King’s College London, London, UK
Joshua L Roffman
72Athinoula A. Martinos Center, Massachusetts General Hospital, Boston, Massachusetts, USA
74Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
Guy A Rouleau
309Montreal Neurological Institute and Hospital, Montreal, QC Canada
310Department of Neurology and Neurosurgery, McGill University, Faculty of Medicine, Montreal, QC Canada
Panos Roussos
7Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY USA
78Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA
134Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
311Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Dan Rujescu
161Department of Psychiatry, University of Halle, Halle, Germany
162Department of Psychiatry, University of Munich, Munich, Germany
Veikko Salomaa
145National Institute for Health and Welfare, Helsinki, Finland
Cristina Sanchez-Mora
91Department of Psychiatry, Hospital Universitari Vall ďHebron, Barcelona, Spain
92Instituto de Salud Carlos III, Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain
93Psychiatric Genetics Unit, Group of Psychiatry Mental Health and Addictions, Vall ďHebron Research Institut (VHIR), Universitat Autonoma de Barcelona, Barcelona, Spain
Alan R Sanders
30Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, Illinois, USA
137Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem, Evanston, Illinois, USA
Stephen J Sawcer
312Department of Clinical Neurosciences, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK
Ulrich Schall
82Priority Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, Australia
83Schizophrenia Research Institute, Sydney, Australia
Alan F Schatzberg
28Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, California, USA
William A Scheftner
313Rush University Medical Center, Chicago, IL USA
Peter R Schofield
158Neuroscience Research Australia, Sydney, Australia
159School of Medical Sciences, University of New South Wales, Sydney, Australia
Nicholas J Schork
314Scripps Translational Science Institute, La Jolla, California USA
Sibylle G Schwab
315Faculty of Science, Medicine & Health, Univeristy of Wollogong, Australia
Edward M Scolnick
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Laura J Scott
64Center for Statistical Genetics and Department of Biostatistics, University of Michigan, Ann Arbor, Michigan USA
Rodney J Scott
316Hunter New England Health Service, Newcastle, Australia
83Schizophrenia Research Institute, Sydney, Australia
84School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia
Larry J Seidman
127Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
262Massachusetts Mental Health Center Public Psychiatry Division of the Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
Alessandro Serretti
317Department of Biomedical and NeuroMotor Sciences, University of Bologna, Bologna, Italy
Pak C Sham
228Centre for Genomic Sciences, The University of Hong Kong, Hong Kong, China
97Department of Psychiatry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
98State Key Laboratory for Brain and Cognitive Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Cynthia Shannon Weickert
158Neuroscience Research Australia, Sydney, Australia
86School of Psychiatry, University of New South Wales, Sydney, Australia
Tatyana Shehktman
170Department of Psychiatry, University of California San Diego, La Jolla, California USA
Jianxin Shi
318Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA
Paul D Shilling
170Department of Psychiatry, University of California San Diego, La Jolla, California USA
Engilbert Sigurdsson
319Faculty of Medicine, Department of Psychiatry, School of Health Sciences, University of Iceland, Reykjavik, Iceland
Jeremy M Silverman
10Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
320Research and Development, Bronx Veterans Affairs Medical Center, New York, New York, USA
Kang Sim
101Institute of Mental Health, Singapore, Singapore
Claire Slaney
26Department of Psychiatry, Dalhousie University, Halifax, NS Canada
Petr Slominsky
204Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia
Olav B Smeland
321Department of Neurosciences, University of California San Diego, La Jolla, California USA
261Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
19NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Jordan W Smoller
74Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts, USA
156Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts, USA
4Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Hon-Cheong So
97Department of Psychiatry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Janet L Sobell
322Psychiatry and the Behavioral Sciences, University of Southern California, Los Angeles, California USA
Erik Soderman
17Department of Clinical Neuroscience, Psychiatry Section, Karolinska Institutet, Stockholm, Sweden
Christine Soholm Hansen
40Statens Serum Institut, Copenhagen, Denmark
Chris C A Spencer
42Wellcome Trust Centre for Human Genetics, Oxford, UK
Anne T Spijker
323Mood Disorders, PsyQ, Rotterdam, The Netherlands
David St Clair
324University of Aberdeen, Institute of Medical Sciences, Aberdeen, UK
Hreinn Stefansson
325deCODE Genetics / Amgen, Reykjavik, Iceland
Kari Stefansson
325deCODE Genetics / Amgen, Reykjavik, Iceland
326Faculty of Medicine, University of Iceland, Reykjavik, Iceland
Stacy Steinberg
325deCODE Genetics / Amgen, Reykjavik, Iceland
Elisabeth Stogmann
327Department of Clinical Neurology, Medical University of Vienna, Wien, Austria
Eystein Stordal
328Department of Neuroscience, Norges Teknisk Naturvitenskapelige Universitet Fakultet for naturvitenskap og teknologi, Trondheim, Norway
329Department of Psychiatry, Hospital Namsos, Namsos, Norway
Amy Strange
42Wellcome Trust Centre for Human Genetics, Oxford, UK
Richard E Straub
330Lieber Institute for Brain Development, Baltimore, Maryland, USA
John S Strauss
331Centre for Addiction and Mental Health, Toronto, ON Canada
202Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
Fabian Streit
153Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Mannheim, Germany
Eric Strengman
332Department of Medical Genetics, University Medical Centre Utrecht, Universiteitsweg, Utrecht, The Netherlands
41Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
Jana Strohmaier
153Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Mannheim, Germany
T Scott Stroup
231Department of Psychiatry, Columbia University, New York, New York, USA
Zhan Su
42Wellcome Trust Centre for Human Genetics, Oxford, UK
Mythily Subramaniam
333Institute of Mental Health, Singapore, Singapore
Jaana Suvisaari
237Department of Mental Health and substance Abuse Services; National Institute for Health and Welfare, Helsinki, Finland
Dragan M Svrakic
102Department of Psychiatry, Washington University, St. Louis, Missouri, USA
Jin P Szatkiewicz
113Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA
Szabolcs Szelinger
334Neurogenomics, TGen, Los Angeles, AZ USA
Avazeh Tashakkori-Ghanbaria
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Srinivas Thirumalai
335Berkshire Healthcare NHS Foundation Trust, Bracknell, UK
Robert C Thompson
257Department of Psychiatry, University of Michigan, Ann Arbor, MI USA
Thorgeir E Thorgeirsson
325deCODE Genetics / Amgen, Reykjavik, Iceland
Draga Toncheva
199Department of Medical Genetics, Medical University, Sofia, Bulgaria
Paul A Tooney
336Priority Research Centre for Translational Neuroscience and Mental Health, University of Newcastle, Newcastle, Australia
83Schizophrenia Research Institute, Sydney, Australia
84School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia
Sarah Tosato
337Section of Psychiatry, University of Verona, Verona, Italy
Timothea Toulopoulou
338Department of Psychology, The Jockey Club Tower, 6/F, the Centennial Campus, Pokfulam Road, The University of Hong Kong, Hong Kong, China
Richard C Trembath
250Department of Medical and Molecular Genetics, School of Medicine, King’s College London, Guy’s Hospital, London, UK
Jens Treutlein
153Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Mannheim, Germany
Vassily Trubetskoy
3Department of Psychiatry and Psychotherapy, Charite - Universitatsmedizin, Berlin, Germany
Gustavo Turecki
339Department of Psychiatry, McGill University, Montreal, QC Canada
Arne E Vaaler
340Dept of Psychiatry, Sankt Olavs Hospital Universitetssykehuset i Trondheim, Trondheim, Norway
Helmut Vedder
341Psychiatry, Psychiatrisches Zentrum Nordbaden, Wiesloch, Germany
Eduard Vieta
342Clinical Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain
John Vincent
331Centre for Addiction and Mental Health, Toronto, ON Canada
Peter M Visscher
8Queensland Brain Institute, The University of Queensland, Brisbane, Australia
Ananth C Viswanathan
343Institute of Ophthalmology, University College London, London, UK
344National Institute for Health Research, Biomedical Research Centre at Moorfields Eye Hospital, National Health Service Foundation Trust, London, UK
Damjan Vukcevic
42Wellcome Trust Centre for Human Genetics, Oxford, UK
John Waddington
345Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland
Matthew Waller
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Dermot Walsh
346Health Research Board, Dublin, Ireland
Muriel Walshe
37Institute of Psychiatry at King’s College London, London, UK
James TR Walters
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
Dai Wang
166Neuroscience Therapeutic Area, Janssen Research and Development, Raritan, New Jersey, USA
Qiang Wang
229Mental Health Centre and Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, Sichuan, China
Weiqing Wang
7Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY USA
10Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Yunpeng Wang
178Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services Copenhagen, Denmark
347Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Stanley J Watson
257Department of Psychiatry, University of Michigan, Ann Arbor, MI USA
Bradley T Webb
38Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA
Thomas W Weickert
158Neuroscience Research Australia, Sydney, Australia
86School of Psychiatry, University of New South Wales, Sydney, Australia
Daniel R Weinberger
348Departments of Psychiatry, Neurology, Neuroscience and Institute of Genetic Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
330Lieber Institute for Brain Development, Baltimore, Maryland, USA
Matthias Weisbrod
54Section for Experimental Psychopathology, General Psychiatry, Heidelberg, Germany
Mark Weiser
122Sheba Medical Center, Tel Hashomer, Israel
Thomas Werge
349Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
178Institute of Biological Psychiatry, Mental Health Centre Sct. Hans, Mental Health Services Copenhagen, Denmark
22The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark
Paul Weston
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Pamela Whittaker
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Sara Widaa
44Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Durk Wiersma
350Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
Dieter B Wildenauer
190School of Psychiatry and Clinical Neurosciences, The University of Western Australia, Perth, Australia
Nigel M Williams
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
Stephanie Williams
113Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA
Stephanie H Witt
153Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Mannheim, Germany
Aaron R Wolen
306Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia, USA
Emily HM Wong
97Department of Psychiatry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Nicholas W Wood
351Department of Molecular Neuroscience, Institute of Neurology, London, UK
Brandon K Wormley
38Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA
23Molecular & Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI USA
52UMR-S1144 Team 1: Biomarkers of relapse and therapeutic response in addiction and mood disorders, INSERM, Paris, France
Jing Qin Wu
83Schizophrenia Research Institute, Sydney, Australia
84School of Biomedical Sciences and Pharmacy, University of Newcastle, Callaghan, Australia
Simon Xi
353Computational Sciences Center of Emphasis, Pfizer Global Research and Development, Cambridge, MA USA
Wei Xu
354Dalla Lana School of Public Health, University of Toronto, Toronto, ON Canada
355Department of Biostatistics, Princess Margaret Cancer Centre, Toronto, ON Canada
Allan H Young
356Psychological Medicine, Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, UK
Clement C Zai
201Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
302Department of Functional Genomics, Center for Neurogenomics and Cognitive Research, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands
Peter Zandi
357Department of Mental Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD USA
Peng Zhang
358Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD USA
Xuebin Zheng
235Human Genetics, Genome Institute of Singapore, A∗STAR, Singapore, Singapore
Fritz Zimprich
327Department of Clinical Neurology, Medical University of Vienna, Wien, Austria
Sebastian Zollner
257Department of Psychiatry, University of Michigan, Ann Arbor, MI USA
Aiden Corvin
163Neuropsychiatric Genetics Research Group, Dept of Psychiatry and Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland
Ayman H Fanous
359Department of Psychiatry, Institute for Genomic Health SUNY Downstate Medical Center Brooklyn, NY, USA
Sven Cichon
124Life&Brain Center, Department of Genomics, University of Bonn, Bonn, Germany
183Department of Biomedicine, University of Basel, Basel, Switzerland
125Institute of Human Genetics, University of Bonn, Bonn, Germany
271Institute of Neuroscience and Medicine (INM-1), Research Center Juelich, Juelich, Germany
185Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland
Marcella Rietschel
153Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Mannheim, Germany
Elliot S Gershon
360Departments of Psychiatry and Human Genetics, University of Chicago, Chicago, Illinois, USA
Thomas G Schulze
153Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Mannheim, Germany
129Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
160Department of Psychiatry and Psychotherapy, University Medical Center Gottingen, Gottingen, Germany
260Human Genetics Branch, Intramural Research Program, National Institute of Mental Health, Bethesda, MD USA
14Institute of Psychiatric Phenomics and Genomics (IPPG), Medical Center of the University of Munich, Munich, Germany
Alfredo B Cuellar-Barboza
361Universidad Autonoma de Nuevo Leon, Department of Psychiatry, Monterrey, Mexico; Department of Psychiatry, Mayo Clinic, MN, USA
Andreas J Forstner
183Department of Biomedicine, University of Basel, Basel, Switzerland
362Department of Psychiatry (UPK), University of Basel, Basel, Switzerland
125Institute of Human Genetics, University of Bonn, Bonn, Germany
124Life&Brain Center, Department of Genomics, University of Bonn, Bonn, Germany
Peter A Holmans
29Medical Research Council Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
109National Centre for Mental Health, Cardiff University, Cardiff, UK
John I Nurnberger
363Department of Psychiatry and Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN USA
Ole A Andreassen
261Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
19NORMENT, KG Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
S Hong Lee
8Queensland Brain Institute, The University of Queensland, Brisbane, Australia
Michael C O’Donovan
87MRC Centre for Neuropsychiatric Genetics and Genomics, Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
109National Centre for Mental Health, Cardiff University, Cardiff, UK
Patrick F Sullivan
113Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA
57Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
296Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina USA
Roel A Ophoff
11Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA
41Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, Utrecht, The Netherlands
Naomi R Wray
266Institute for Molecular Bioscience, The University of Queensland, Brisbane, Australia
8Queensland Brain Institute, The University of Queensland, Brisbane, Australia
Pamela Sklar
7Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY USA
78Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA
79Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA
311Institute for Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA
Kenneth S Kendler
364Virginia Institute for Psychiatric and Behavioral Genetics and Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA
Abstract
Schizophrenia (SCZ) and bipolar disorder (BD) are highly heritable disorders that share a significant proportion of common risk variation. Understanding the genetic factors underlying the specific symptoms of these disorders will be crucial for improving diagnosis, intervention and treatment. In case-control data consisting of 53,555 cases (20,129 BD, 33,426 SCZ) and 54,065 controls, we identified 114 genome-wide significant loci (GWS) when comparing all cases to controls, of which 41 represented novel findings. Two genome-wide significant loci were identified when comparing SCZ to BD and a third was found when directly incorporating functional information. Regional joint association identified a genomic region of overlapping association in BD and SCZ with disease-independent causal variants indicating a fourth region contributing to differences between these disorders. Regional SNP-heritability analyses demonstrated that the estimated heritability of BD based on the SCZ GWS regions was significantly higher than that based on the average genomic region (91 regions, p = 1.2×10−6) while the inverse was not significant (19 regions, p=0.89). Using our BD and SCZ GWAS we calculated polygenic risk scores and identified several significant correlations with: 1) SCZ subphenotypes: negative symptoms (SCZ, p=3.6×10−6) and manic symptoms (BD, p=2×10−5), 2) BD subphenotypes: psychotic features (SCZ p=1.2×10−10, BD p=5.3×10−5) and age of onset (SCZ p=7.9×10−4). Finally, we show that psychotic features in BD has significant SNP-heritability (h2 snp=0.15, SE=0.06), and a significant genetic correlation with SCZ (rg=0.34) in addition there is a significant sign test result between SCZ GWAS and a GWAS of BD cases contrasting those with and without psychotic features (p=0.0038, one-side binomial test). For the first time, we have identified specific loci pointing to a potential role of 4 genes (DARS2, ARFGEF2, DCAKD and GATAD2A) that distinguish between BD and SCZ, providing an opportunity to understand the biology contributing to clinical differences of these disorders. Our results provide the best evidence so far of genomic components distinguishing between BD and SCZ that contribute directly to specific symptom dimensions.
Copyright
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Posted August 08, 2017.
Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes
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Kalman, Rolf Adolfsson, Ingrid Agartz, Esben Agerbo, Huda Akil, Diego Albani, Margot Albus, Martin Alda, Madeline Alexander, Judith Allardyce, Ney Alliey-Rodriguez, Thomas D Als, Farooq Amin, Adebayo Anjorin, Maria J Arranz, Swapnil Awasthi, Silviu A Bacanu, Judith A Badner, Marie Baekvad-Hansen, Steven Bakker, Gavin Band, Jack D Barchas, Ines Barroso, Nicholas Bass, Michael Bauer, Bernhard T Baune, Martin Begemann, Celine Bellenguez, Richard A Belliveau Jr, Frank Bellivier, Stephan Bender, Judit Bene, Sarah E Bergen, Wade H Berrettini, Elizabeth Bevilacqua, Joanna M Biernacka, Tim B Bigdeli, Donald W Black, Hannah Blackburn, Jenefer M Blackwell, Douglas HR Blackwood, Carsten Bocker Pedersen, Michael Boehnke, Marco Boks, Anders D Borglum, Elvira Bramon, Gerome Breen, Matthew A Brown, Richard Bruggeman, Nancy G Buccola, Randy L Buckner, Monika Budde, Brendan Bulik-Sullivan, Suzannah J Bumpstead, William Bunney, Margit Burmeister, Joseph D Buxbaum, Jonas Bybjerg-Grauholm, William 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