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Propofol induces metabolic reprogramming and cell death in a mitochondrial electron transport chain-dependent manner

Chisato Sumi, Akihisa Okamoto, Hiromasa Tanaka, Kenichiro Nishi, Munenori Kusunoki, Tomohiro Shoji, Takeo Uba, Yoshiyuki Matsuo, Takehiko Adachi, Jun-Ichi Hayashi, Keizo Takenaga, View ORCID ProfileKiichi Hirota
doi: https://doi.org/10.1101/181933
Chisato Sumi
Institute of Biomedical Science, Kansai Medical University;
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Akihisa Okamoto
Institute of Biomedical Science, Kansai Medical University;
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Hiromasa Tanaka
Institute of Biomedical Science, Kansai Medical University;
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Kenichiro Nishi
Institute of Biomedical Science, Kansai Medical University;
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Munenori Kusunoki
Institute of Biomedical Science, Kansai Medical University;
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Tomohiro Shoji
Institute of Biomedical Science, Kansai Medical University;
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Takeo Uba
Institute of Biomedical Science, Kansai Medical University;
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Yoshiyuki Matsuo
Institute of Biomedical Science, Kansai Medical University;
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Takehiko Adachi
Department of Anesthesiology, Tazuke Kofukai Medical Institute Kitano Hospital;
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Jun-Ichi Hayashi
University of Tsukuba;
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Keizo Takenaga
Department of Life Science, Shimane University Faculty of Medicine
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Kiichi Hirota
Institute of Biomedical Science, Kansai Medical University;
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  • ORCID record for Kiichi Hirota
  • For correspondence: hif1@mac.com
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Article Information

doi 
https://doi.org/10.1101/181933
History 
  • November 16, 2017.

Article Versions

  • older version (September 10, 2017 - 08:10).
  • You are viewing the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Chisato Sumi1 (chisato13150labo{at}gmail.com),
  2. Akihisa Okamoto1 (aokamoto1978{at}gmail.com),
  3. Hiromasa Tanaka1 (0212291hiro{at}gmail.com),
  4. Kenichiro Nishi1 (nishik{at}hirakata.kmu.ac.jp),
  5. Munenori Kusunoki1 (moo1029taka{at}gmail.com),
  6. Tomohiro Shoji1 (tomohiro.shoji.1020{at}gmail.com),
  7. Takeo Uba1 (snatcher0517{at}gmail.com),
  8. Yoshiyuki Matsuo1 (matsuo.oustam{at}gmail.com),
  9. Takehiko Adachi2 (t-adachi{at}kitano-hp.or.jp),
  10. Jun-Ichi Hayashi3 (jih45{at}biol.tsukuba.ac.jp),
  11. Keizo Takenaga4 (biokeizo{at}med.shimane-u.ac.jp) and
  12. Kiichi Hirota1,5 (hif1{at}mac.com)
  1. 1 Institute of Biomedical Science, Kansai Medical University;
  2. 2 Department of Anesthesiology, Tazuke Kofukai Medical Institute Kitano Hospital;
  3. 3 University of Tsukuba;
  4. 4 Department of Life Science, Shimane University Faculty of Medicine
  1. ↵* Corresponding author; email: hif1{at}mac.com
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Posted November 16, 2017.
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Propofol induces metabolic reprogramming and cell death in a mitochondrial electron transport chain-dependent manner
Chisato Sumi, Akihisa Okamoto, Hiromasa Tanaka, Kenichiro Nishi, Munenori Kusunoki, Tomohiro Shoji, Takeo Uba, Yoshiyuki Matsuo, Takehiko Adachi, Jun-Ichi Hayashi, Keizo Takenaga, Kiichi Hirota
bioRxiv 181933; doi: https://doi.org/10.1101/181933
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Propofol induces metabolic reprogramming and cell death in a mitochondrial electron transport chain-dependent manner
Chisato Sumi, Akihisa Okamoto, Hiromasa Tanaka, Kenichiro Nishi, Munenori Kusunoki, Tomohiro Shoji, Takeo Uba, Yoshiyuki Matsuo, Takehiko Adachi, Jun-Ichi Hayashi, Keizo Takenaga, Kiichi Hirota
bioRxiv 181933; doi: https://doi.org/10.1101/181933

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