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Streptolysin-induced endoplasmic reticulum stress promotes group A streptococcal in vivo biofilm formation and necrotizing fasciitis
Anuradha Vajjala, Debabrata Biswas, Kelvin Kian Long Chong, Wei Hong Tay, Emanuel Hanski, View ORCID ProfileKimberly A Kline
doi: https://doi.org/10.1101/183012
Anuradha Vajjala
aSingapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, SBS-B1n-27, 60 Nanyang Drive, Singapore 637551;
bSchool of Biological Sciences, Nanyang Technological University, SBS-B2n-27, 60 Nanyang Drive, Singapore 637551;
Debabrata Biswas
cNational University of Singapore (NUS)-The Hebrew University of Jerusalem (HUJ), Mechanisms of Inflammation, Campus for Research Excellence & Technological Enterprise (CREATE), NUS, Singapore 138602;
Kelvin Kian Long Chong
aSingapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, SBS-B1n-27, 60 Nanyang Drive, Singapore 637551;
dNanyang Institute of Technology in Health and Medicine (NITHM), Research Techno Plaza, Nanyang Technological University, XFrontiers Block #02-07, 50 Nanyang Drive, Singapore 637553;
Wei Hong Tay
aSingapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, SBS-B1n-27, 60 Nanyang Drive, Singapore 637551;
eSingapore Centre for Environmental Life Sciences Engineering, Interdisciplinary Graduate School, Nanyang Technological University, SBS-B2n-27, 60 Nanyang Drive, Singapore 637551;
Emanuel Hanski
cNational University of Singapore (NUS)-The Hebrew University of Jerusalem (HUJ), Mechanisms of Inflammation, Campus for Research Excellence & Technological Enterprise (CREATE), NUS, Singapore 138602;
fDept. of Microbiology and Molecular Genetics, IMRIC, The Hebrew University of Jerusalem, Faculty of Medicine, Jerusalem 91120, Israel.
Kimberly A Kline
aSingapore Centre for Environmental Life Sciences Engineering, Nanyang Technological University, SBS-B1n-27, 60 Nanyang Drive, Singapore 637551;
bSchool of Biological Sciences, Nanyang Technological University, SBS-B2n-27, 60 Nanyang Drive, Singapore 637551;
Posted August 31, 2017.
Streptolysin-induced endoplasmic reticulum stress promotes group A streptococcal in vivo biofilm formation and necrotizing fasciitis
Anuradha Vajjala, Debabrata Biswas, Kelvin Kian Long Chong, Wei Hong Tay, Emanuel Hanski, Kimberly A Kline
bioRxiv 183012; doi: https://doi.org/10.1101/183012
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