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- January 26, 2018.
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- Version 1 (September 6, 2017 - 13:24).
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- Stefan Gräf#,$,*,1,2,3,
- Matthias Haimel#,1,2,3,
- Marta Bleda#,1,
- Charaka Hadinnapola#,1,
- Laura Southgate#,4,5,
- Wei Li1,
- Joshua Hodgson1,
- Bin Liu1,
- Richard M. Salmon1,
- Mark Southwood6,
- Rajiv D. Machado7,
- UK PAH Cohort Study Consortium,
- NIHR BioResource – Rare Disease Consortium,
- Jennifer M. Martin1,2,3,
- Carmen M. Treacy1,6,
- Katherine Yates1,2,3,
- Louise C. Daugherty2,3,
- Olga Shamardina2,3,
- Deborah Whitehorn2,3,
- Simon Holden8,
- Micheala Aldred9,
- Harm J. Bogaard10,
- Colin Church11,
- Gerry Coghlan12,
- Robin Condliffe13,
- Paul A. Corris14,
- Cesare Danesino15,16,
- Mélanie Eyries17,
- Henning Gall18,
- Stefano Ghio16,
- Hossein-Ardeschir Ghofrani18,19,
- J. Simon R. Gibbs20,
- Barbara Girerd21,
- Arjan C. Houweling10,
- Luke Howard19,
- Marc Humbert21,
- David G. Kiely13,
- Gabor Kovacs22,23,
- Robert V. MacKenzie Ross24,
- Shahin Moledina25,
- David Montani21,
- Michael Newnham1,
- Andrea Olschewski22,
- Horst Olschewski22,23,
- Andrew J. Peacock11,
- Joanna Pepke-Zaba6,
- Inga Prokopenko19,
- Christopher J. Rhodes19,
- Laura Scelsi16,
- Werner Seeger18,
- Florent Soubrier17,
- Dan F. Stein1,
- Jay Suntharalingam24,
- Emilia Swietlik1,
- Mark R. Toshner1,
- Anton Vonk Noordegraaf10,
- David A. van Heel26,
- Quinten Waisfisz10,
- John Wharton19,
- Stephen J. Wort27,19,
- Willem H. Ouwehand2,3,
- Nicole Soranzo2,28,
- Allan Lawrie29,
- Paul D. Upton1,
- Martin R. Wilkins19,
- Richard C. Trembath5 and
- Nicholas W. Morrell$,*,1,3
- 1Department of Medicine, University of Cambridge, Cambridge, United Kingdom;
- 2Department of Haematology, University of Cambridge, Cambridge, United Kingdom;
- 3NIHR BioResource - Rare Diseases, Cambridge, United Kingdom;
- 4Molecular and Clinical Sciences Research Institute, St George’s, University of London, London, United Kingdom;
- 5Division of Genetics & Molecular Medicine, King’s College London, London, United Kingdom;
- 6Papworth Hospital, Papworth, United Kingdom;
- 7Institute of Medical and Biomedical Education, St George’s University of London, London, United Kingdom;
- 8Addenbrooke’s Hospital, Cambridge, United Kingdom;
- 9Cleveland Clinic, Cleveland, Ohio, United States;
- 10VU University Medical Center, Amsterdam, The Netherlands;
- 11Golden Jubilee National Hospital, Glasgow, United Kingdom;
- 12Royal Free Hospital, London, United Kingdom;
- 13Sheffield Pulmonary Vascular Disease Unit, Royal Hallamshire Hospital, Sheffield, United Kingdom;
- 14University of Newcastle, Newcastle, United Kingdom;
- 15Department of Molecular Medicine, University of Pavia, Pavia, Italy;
- 16Fondazione IRCCS Policlinico San Matteo, Pavia, Italy;
- 17Département de génétique, hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, and UMR_S 1166-ICAN, INSERM, UPMC Sorbonne Universités, Paris, France;
- 18University of Giessen and Marburg Lung Center (UGMLC), member of the German Center for Lung Research (DZL) and of the Excellence Cluster Cardio-Pulmonary System (ECCCPS), Giessen, Germany;
- 19Imperial College London, London, United Kingdom;
- 20National Heart & Lung Institute, Imperial College London, London, United Kingdom;
- 21Université Paris-Sud, Faculté de Médecine, Université Paris-Saclay; AP-HP, Service de Pneumologie, Centre de référence de l’hypertension pulmonaire; INSERM UMR_S 999, Hôpital Bicêtre, Le Kremlin-Bicêtre, Paris, France;
- 22Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria;
- 23Medical University of Graz, Graz, Austria;
- 24Royal United Hospitals Bath NHS Foundation Trust, Bath, United Kingdom;
- 25Great Ormond Street Hospital, London, United Kingdom;
- 26Blizard Institute, Queen Mary University of London, London, United Kingdom
- 27Royal Brompton Hospital, London, United Kingdom;
- 28Wellcome Trust Sanger Institute, Hinxton, United Kingdom;
- 29Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Sheffield, United Kingdom
- ↵*corresponding authors, Address for correspondence: Prof Nicholas Morrell, (nwm23{at}cam.ac.uk), and Dr Stefan Gräf, (sg550{at}cam.ac.uk), Department of Medicine, University of Cambridge School of Clinical Medicine, Addenbrooke’s Hospital, Hills Road, Cambridge CB2 0QQ, United Kingdom
↵# these authors contributed equally