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In Silico Mechanobiochemical Modeling of Morphogenesis in Cell Monolayers

Bahador Marzban, Xiao Ma, Xiaoliang Qing, View ORCID ProfileHongyan Yuan
doi: https://doi.org/10.1101/189175
Bahador Marzban
1Department of Mechanical, Industrial & Systems Engineering, University of Rhode Island, Kingston, RI 02881, USA
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Xiao Ma
2Danuser Lab, The University of Texas Southwestern Medical Center, USA
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Xiaoliang Qing
3Department of Mechanical Engineering, FuJian University of Technology, Fujian, China
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Hongyan Yuan
1Department of Mechanical, Industrial & Systems Engineering, University of Rhode Island, Kingston, RI 02881, USA
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  • ORCID record for Hongyan Yuan
  • For correspondence: hongyan_yuan@uri.edu
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  • Movie S1 Change of migration direction due to the nature of the reaction-diffusion submodel
  • Movie S2 Persistent migration direction with the cytoskeleton asymmetry
  • Movie S3 Durotaxis - the cell turns at the rigid-to-soft substrate interaction
  • Movie S4 At smaller force-dependent protrusion signal generation, the cell passes the interface without turning
  • Movie S5 Cellular dynamics of cell monolayer, without cell-cell adhesion
  • Movie S6 Cellular dynamics of cell monolayer, with cell-cell adhsion
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Posted February 13, 2018.
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In Silico Mechanobiochemical Modeling of Morphogenesis in Cell Monolayers
Bahador Marzban, Xiao Ma, Xiaoliang Qing, Hongyan Yuan
bioRxiv 189175; doi: https://doi.org/10.1101/189175
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In Silico Mechanobiochemical Modeling of Morphogenesis in Cell Monolayers
Bahador Marzban, Xiao Ma, Xiaoliang Qing, Hongyan Yuan
bioRxiv 189175; doi: https://doi.org/10.1101/189175

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