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Fibril branching dominates self-assembly of mutant huntingtin exon-1 aggregates in vitro
Anne S. Wagner, Antonio Z. Politi, Anne Steinhof, Kenny Bravo-Rodriguez, Alexander Buntru, Nadine U. Strempel, Lydia Brusendorf, Christian Hänig, Annett Boeddrich, Stephanie Plassmann, Juan M. Ramirez-Anguita, Katharina Baum, Elsa Sanchez-Garcia, Jana Wolf, Erich E. Wanker
doi: https://doi.org/10.1101/195297
Anne S. Wagner
1Neuroproteomics, Max Delbrueck Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
Antonio Z. Politi
2Mathematical Modelling of Cellular Processes, Max Delbrueck Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
3Present address: European Molecular Biology Laboratory (EMBL), Meyerhofstraße 1, 69117 Heidelberg, Germany
Anne Steinhof
1Neuroproteomics, Max Delbrueck Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
Kenny Bravo-Rodriguez
4Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 2, 45470 Mülheim an der Ruhr, Germany
5Computational Chemistry and Biology, University Duisburg-Essen, Universitätsstr. 5, 45141 Essen, Germany
Alexander Buntru
1Neuroproteomics, Max Delbrueck Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
Nadine U. Strempel
1Neuroproteomics, Max Delbrueck Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
Lydia Brusendorf
1Neuroproteomics, Max Delbrueck Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
Christian Hänig
1Neuroproteomics, Max Delbrueck Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
Annett Boeddrich
1Neuroproteomics, Max Delbrueck Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
Stephanie Plassmann
1Neuroproteomics, Max Delbrueck Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
Juan M. Ramirez-Anguita
4Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 2, 45470 Mülheim an der Ruhr, Germany
Katharina Baum
2Mathematical Modelling of Cellular Processes, Max Delbrueck Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
Elsa Sanchez-Garcia
4Max-Planck-Institut für Kohlenforschung, Kaiser-Wilhelm-Platz 2, 45470 Mülheim an der Ruhr, Germany
5Computational Chemistry and Biology, University Duisburg-Essen, Universitätsstr. 5, 45141 Essen, Germany
Jana Wolf
2Mathematical Modelling of Cellular Processes, Max Delbrueck Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
Erich E. Wanker
1Neuroproteomics, Max Delbrueck Center for Molecular Medicine, Robert-Rössle-Straße 10, 13125 Berlin, Germany
Posted October 19, 2017.
Fibril branching dominates self-assembly of mutant huntingtin exon-1 aggregates in vitro
Anne S. Wagner, Antonio Z. Politi, Anne Steinhof, Kenny Bravo-Rodriguez, Alexander Buntru, Nadine U. Strempel, Lydia Brusendorf, Christian Hänig, Annett Boeddrich, Stephanie Plassmann, Juan M. Ramirez-Anguita, Katharina Baum, Elsa Sanchez-Garcia, Jana Wolf, Erich E. Wanker
bioRxiv 195297; doi: https://doi.org/10.1101/195297
Fibril branching dominates self-assembly of mutant huntingtin exon-1 aggregates in vitro
Anne S. Wagner, Antonio Z. Politi, Anne Steinhof, Kenny Bravo-Rodriguez, Alexander Buntru, Nadine U. Strempel, Lydia Brusendorf, Christian Hänig, Annett Boeddrich, Stephanie Plassmann, Juan M. Ramirez-Anguita, Katharina Baum, Elsa Sanchez-Garcia, Jana Wolf, Erich E. Wanker
bioRxiv 195297; doi: https://doi.org/10.1101/195297
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