Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

The VT GAL4, LexA, and split-GAL4 driver line collections for targeted expression in the Drosophila nervous system

Laszlo Tirian, Barry J. Dickson
doi: https://doi.org/10.1101/198648
Laszlo Tirian
1Research Institute of Molecular Pathology, Campus-Vienna-Biocenter 1, A-1030 Vienna, Austria
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Barry J. Dickson
1Research Institute of Molecular Pathology, Campus-Vienna-Biocenter 1, A-1030 Vienna, Austria
2Janelia Research Campus, HHMI, 19700 Helix Drive, Ashburn VA, 21407, U.S.A.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: dicksonb@janelia.hhmi.org
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Preview PDF
Loading

Abstract

In studying the cellular interactions within complex tissues, it is extremely valuable to be able to reproducibly and flexibly target transgene expression to restricted subsets of cells. This approach is particularly valuable in studying the nervous system, with its bewildering diversity of neuronal cell types. We report here the generation of over 18,000 driver lines (the VT collection) that exploit the GAL4, LexA, and split-GAL4 systems to express transgenes in distinct and highly specific cell types in Drosophila. We document the expression patterns of over 14,000 of these lines in the adult male brain.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.
Back to top
PreviousNext
Posted October 05, 2017.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
The VT GAL4, LexA, and split-GAL4 driver line collections for targeted expression in the Drosophila nervous system
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
The VT GAL4, LexA, and split-GAL4 driver line collections for targeted expression in the Drosophila nervous system
Laszlo Tirian, Barry J. Dickson
bioRxiv 198648; doi: https://doi.org/10.1101/198648
Digg logo Reddit logo Twitter logo Facebook logo Google logo LinkedIn logo Mendeley logo
Citation Tools
The VT GAL4, LexA, and split-GAL4 driver line collections for targeted expression in the Drosophila nervous system
Laszlo Tirian, Barry J. Dickson
bioRxiv 198648; doi: https://doi.org/10.1101/198648

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Neuroscience
Subject Areas
All Articles
  • Animal Behavior and Cognition (3497)
  • Biochemistry (7341)
  • Bioengineering (5317)
  • Bioinformatics (20248)
  • Biophysics (9999)
  • Cancer Biology (7734)
  • Cell Biology (11291)
  • Clinical Trials (138)
  • Developmental Biology (6431)
  • Ecology (9943)
  • Epidemiology (2065)
  • Evolutionary Biology (13311)
  • Genetics (9358)
  • Genomics (12575)
  • Immunology (7696)
  • Microbiology (18998)
  • Molecular Biology (7432)
  • Neuroscience (40971)
  • Paleontology (300)
  • Pathology (1228)
  • Pharmacology and Toxicology (2133)
  • Physiology (3154)
  • Plant Biology (6855)
  • Scientific Communication and Education (1272)
  • Synthetic Biology (1895)
  • Systems Biology (5309)
  • Zoology (1087)