New Results
TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids
Momoko Watanabe, Jillian R. Haney, Neda Vishlaghi, Felix Turcios, Jessie E. Buth, Wen Gu, Amanda J. Collier, Osvaldo A. Miranda, Di Chen, Shan Sabri, Amander T. Clark, Kathrin Plath, Heather R. Christofk, Michael J. Gandal, View ORCID ProfileBennett G. Novitch
doi: https://doi.org/10.1101/2019.12.13.875773
Momoko Watanabe
1Department of Neurobiology, David Geffen School of Medicine at UCLA
2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
3Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA
Jillian R. Haney
3Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA
4Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA
7Equal Contributions
Neda Vishlaghi
1Department of Neurobiology, David Geffen School of Medicine at UCLA
2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
7Equal Contributions
Felix Turcios
1Department of Neurobiology, David Geffen School of Medicine at UCLA
2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
Jessie E. Buth
1Department of Neurobiology, David Geffen School of Medicine at UCLA
2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
Wen Gu
2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
5Department of Biological Chemistry, David Geffen School of Medicine at UCLA
Amanda J. Collier
2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
6Department of Molecular, Cellular, and Developmental Biology University of California Los Angeles, Los Angeles, CA 90095, USA
Osvaldo A. Miranda
1Department of Neurobiology, David Geffen School of Medicine at UCLA
2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
Di Chen
2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
6Department of Molecular, Cellular, and Developmental Biology University of California Los Angeles, Los Angeles, CA 90095, USA
Shan Sabri
2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
5Department of Biological Chemistry, David Geffen School of Medicine at UCLA
Amander T. Clark
2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
6Department of Molecular, Cellular, and Developmental Biology University of California Los Angeles, Los Angeles, CA 90095, USA
Kathrin Plath
2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
5Department of Biological Chemistry, David Geffen School of Medicine at UCLA
Heather R. Christofk
2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
5Department of Biological Chemistry, David Geffen School of Medicine at UCLA
Michael J. Gandal
3Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA
4Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA
Bennett G. Novitch
1Department of Neurobiology, David Geffen School of Medicine at UCLA
2Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
3Intellectual and Developmental Disabilities Research Center, Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine at UCLA
8Lead Contact
Posted December 13, 2019.
TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids
Momoko Watanabe, Jillian R. Haney, Neda Vishlaghi, Felix Turcios, Jessie E. Buth, Wen Gu, Amanda J. Collier, Osvaldo A. Miranda, Di Chen, Shan Sabri, Amander T. Clark, Kathrin Plath, Heather R. Christofk, Michael J. Gandal, Bennett G. Novitch
bioRxiv 2019.12.13.875773; doi: https://doi.org/10.1101/2019.12.13.875773
TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids
Momoko Watanabe, Jillian R. Haney, Neda Vishlaghi, Felix Turcios, Jessie E. Buth, Wen Gu, Amanda J. Collier, Osvaldo A. Miranda, Di Chen, Shan Sabri, Amander T. Clark, Kathrin Plath, Heather R. Christofk, Michael J. Gandal, Bennett G. Novitch
bioRxiv 2019.12.13.875773; doi: https://doi.org/10.1101/2019.12.13.875773
Subject Area
Subject Areas
- Biochemistry (11730)
- Bioengineering (8743)
- Bioinformatics (29179)
- Biophysics (14963)
- Cancer Biology (12080)
- Cell Biology (17399)
- Clinical Trials (138)
- Developmental Biology (9417)
- Ecology (14173)
- Epidemiology (2067)
- Evolutionary Biology (18294)
- Genetics (12233)
- Genomics (16791)
- Immunology (11858)
- Microbiology (28051)
- Molecular Biology (11575)
- Neuroscience (60918)
- Paleontology (451)
- Pathology (1870)
- Pharmacology and Toxicology (3238)
- Physiology (4955)
- Plant Biology (10422)
- Synthetic Biology (2881)
- Systems Biology (7338)
- Zoology (1650)