Prioritization of enhancer mutations by combining allele-specific chromatin accessibility with deep learning

Zeynep Kalender Atak; Ibrahim Ihsan Taskiran; Christopher Flerin; David Mauduit; Liesbeth Minnoye; Gert Hulsemans; Valerie Christiaens; Ghanem-Elias Ghanem; Jasper Wouters; Stein Aerts

doi:10.1101/2019.12.21.885806

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Prioritization of enhancer mutations by combining allele-specific chromatin accessibility with deep learning

View ORCID ProfileZeynep Kalender Atak, View ORCID ProfileIbrahim Ihsan Taskiran, Christopher Flerin, David Mauduit, Liesbeth Minnoye, Gert Hulsemans, Valerie Christiaens, Ghanem-Elias Ghanem, Jasper Wouters, View ORCID ProfileStein Aerts

doi: https://doi.org/10.1101/2019.12.21.885806

Zeynep Kalender Atak

1VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium

2KU Leuven, Department of Human Genetics KU Leuven, Leuven, Belgium

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ORCID record for Zeynep Kalender Atak

Ibrahim Ihsan Taskiran

1VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium

2KU Leuven, Department of Human Genetics KU Leuven, Leuven, Belgium

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ORCID record for Ibrahim Ihsan Taskiran

Christopher Flerin

1VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium

2KU Leuven, Department of Human Genetics KU Leuven, Leuven, Belgium

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David Mauduit

1VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium

2KU Leuven, Department of Human Genetics KU Leuven, Leuven, Belgium

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Liesbeth Minnoye

1VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium

2KU Leuven, Department of Human Genetics KU Leuven, Leuven, Belgium

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Gert Hulsemans

1VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium

2KU Leuven, Department of Human Genetics KU Leuven, Leuven, Belgium

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Valerie Christiaens

1VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium

2KU Leuven, Department of Human Genetics KU Leuven, Leuven, Belgium

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Ghanem-Elias Ghanem

3Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium

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Jasper Wouters

1VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium

2KU Leuven, Department of Human Genetics KU Leuven, Leuven, Belgium

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Stein Aerts

1VIB-KU Leuven Center for Brain & Disease Research, Leuven, Belgium

2KU Leuven, Department of Human Genetics KU Leuven, Leuven, Belgium

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ORCID record for Stein Aerts
For correspondence: stein.aerts@kuleuven.vib.be

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Posted December 23, 2019.

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Prioritization of enhancer mutations by combining allele-specific chromatin accessibility with deep learning

Zeynep Kalender Atak, Ibrahim Ihsan Taskiran, Christopher Flerin, David Mauduit, Liesbeth Minnoye, Gert Hulsemans, Valerie Christiaens, Ghanem-Elias Ghanem, Jasper Wouters, Stein Aerts

bioRxiv 2019.12.21.885806; doi: https://doi.org/10.1101/2019.12.21.885806

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Prioritization of enhancer mutations by combining allele-specific chromatin accessibility with deep learning

Zeynep Kalender Atak, Ibrahim Ihsan Taskiran, Christopher Flerin, David Mauduit, Liesbeth Minnoye, Gert Hulsemans, Valerie Christiaens, Ghanem-Elias Ghanem, Jasper Wouters, Stein Aerts

bioRxiv 2019.12.21.885806; doi: https://doi.org/10.1101/2019.12.21.885806

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