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History
- December 23, 2019.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Author Information
- Eleanna Kara1,2,
- Alessandro Crimi1,15,
- Anne Wiedmer1,15,
- Marc Emmenegger1,15,
- Claudia Manzoni2,3,
- Sara Bandres-Ciga4,
- Karishma D’Sa2,
- Regina H Reynolds2,
- Juan A Botía2,5,
- Marco Losa1,
- Veronika Lysenko6,
- Manfredi Carta1,
- Daniel Heinzer1,
- Merve Avar1,
- Andra Chincisan1,
- Cornelis Blauwendraat4,
- Sonia Garcia Ruiz2,
- Daniel Pease1,
- Lorene Mottier1,
- Alessandra Carrella1,
- Dezirae Schneider1,
- Andreia Magalhaes1,
- Caroline Aemisegger7,
- Alexandre P A Theocharides6,
- Zhanyun Fan8,
- Jordan D Marks8,9,
- Sarah C Hopp8,10,
- Patrick Lewis2,3,
- Mina Ryten2,
- John Hardy2,11,12,13,
- Bradley T Hyman8 and
- Adriano Aguzzi1,*,14
- 1Institute of Neuropathology, University and University Hospital Zurich, Zurich, 8091, Switzerland
- 2Department of Neurodegenerative disease, University College London, London, WC1N 3BG, United Kingdom
- 3School of Pharmacy, University of Reading, Reading, RG6 6AP, United Kingdom
- 4Laboratory of Neurogenetics, National Institutes of Health, Bethesda, Maryland, 20814, United States
- 5Departamento de Ingeniería de la Información y las Comunicaciones, Universidad de Murcia, Murcia, 30100, Spain
- 6Department of Medical Oncology and Hematology, University and University Hospital Zurich, Zurich, 8091, Switzerland
- 7Center for Microscopy and Image Analysis, University of Zurich, Zurich, 8057, Switzerland
- 8Department of Neurology, Harvard Medical School, Boston, MA, 02129, United States
- 9Mayo Clinic Alix School of medicine, Rochester, MN, 55905, United States
- 10Department of Pharmacology, UT Health San Antonio, San Antonio, 78229, United States
- 11UK Dementia Research Institute at UCL and Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, WC1N 3BG, UK
- 12Reta Lila Weston Institute, UCL Queen Square Institute of Neurology, 1 Wakefield Street, London WC1N 1PJ, UK
- 13Institute for Advanced Study, The Hong Kong University of Science and Technology, Hong Kong SAR, China
- ↵*Corresponding author and lead contact: Adriano Aguzzi, Adriano.aguzzi{at}usz.ch, Institute of Neuropathology, University of Zurich, Schmelzbergstrasse 12, CH-8091 Zurich, Switzerland
↵15 These authors contributed equally