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Crowdsourced mapping extends the target space of kinase inhibitors
View ORCID ProfileAnna Cichonska, View ORCID ProfileBalaguru Ravikumar, View ORCID ProfileRobert J Allaway, Sungjoon Park, Fangping Wan, View ORCID ProfileOlexandr Isayev, Shuya Li, View ORCID ProfileMichael Mason, Andrew Lamb, View ORCID ProfileZiaurrehman Tanoli, View ORCID ProfileMinji Jeon, View ORCID ProfileSunkyu Kim, Mariya Popova, View ORCID ProfileStephen Capuzzi, Jianyang Zeng, Kristen Dang, Gregory Koytiger, View ORCID ProfileJaewoo Kang, View ORCID ProfileCarrow I. Wells, View ORCID ProfileTimothy M. Willson, The IDG-DREAM Drug-Kinase Binding Prediction Challenge Consortium, View ORCID ProfileTudor I. Oprea, View ORCID ProfileAvner Schlessinger, David H. Drewry, View ORCID ProfileGustavo Stolovitzky, View ORCID ProfileKrister Wennerberg, View ORCID ProfileJustin Guinney, View ORCID ProfileTero Aittokallio
doi: https://doi.org/10.1101/2019.12.31.891812
Anna Cichonska
1Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
2Department of Computer Science, Helsinki Institute for Information Technology (HIIT), Aalto University, Espoo, Finland
3Department of Future Technologies, University of Turku, Turku, Finland
Balaguru Ravikumar
1Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
Robert J Allaway
4Computational Oncology, Sage Bionetworks, Seattle, WA, USA
Sungjoon Park
5Department of Computer Science and Engineering, Korea University, Seoul, Republic of Korea
Fangping Wan
6Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China, 100084
Olexandr Isayev
7Department of Chemistry, Carnegie Mellon University, Pittsburgh, PA
Shuya Li
6Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China, 100084
Michael Mason
4Computational Oncology, Sage Bionetworks, Seattle, WA, USA
Andrew Lamb
4Computational Oncology, Sage Bionetworks, Seattle, WA, USA
Ziaurrehman Tanoli
1Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
Minji Jeon
5Department of Computer Science and Engineering, Korea University, Seoul, Republic of Korea
Sunkyu Kim
5Department of Computer Science and Engineering, Korea University, Seoul, Republic of Korea
Mariya Popova
7Department of Chemistry, Carnegie Mellon University, Pittsburgh, PA
Stephen Capuzzi
8Laboratory for Molecular Modeling, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina 27599, United States
Jianyang Zeng
6Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China, 100084
Kristen Dang
4Computational Oncology, Sage Bionetworks, Seattle, WA, USA
Gregory Koytiger
9Immuneering Corporation, Cambridge, MA, USA
Jaewoo Kang
5Department of Computer Science and Engineering, Korea University, Seoul, Republic of Korea
Carrow I. Wells
10Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Timothy M. Willson
10Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Tudor I. Oprea
11Translational Informatics Division and Comprehensive Cancer Center, University of New Mexico School of Medicine, Albuquerque, New Mexico, USA
Avner Schlessinger
12Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA
David H. Drewry
10Structural Genomics Consortium, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
Gustavo Stolovitzky
13IBM T J Watson Research Center, IBM, Yorktown Heights, NY, USA
Krister Wennerberg
14Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark
Justin Guinney
4Computational Oncology, Sage Bionetworks, Seattle, WA, USA
Tero Aittokallio
1Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
2Department of Computer Science, Helsinki Institute for Information Technology (HIIT), Aalto University, Espoo, Finland
15Department of Mathematics and Statistics, University of Turku, Turku, Finland
16Institute for Cancer Research, Oslo University Hospital, Oslo, Norway
17Oslo Centre for Biostatistics and Epidemiology (OCBE), University of Oslo, Oslo, Norway
Article usage
Posted February 11, 2020.
Crowdsourced mapping extends the target space of kinase inhibitors
Anna Cichonska, Balaguru Ravikumar, Robert J Allaway, Sungjoon Park, Fangping Wan, Olexandr Isayev, Shuya Li, Michael Mason, Andrew Lamb, Ziaurrehman Tanoli, Minji Jeon, Sunkyu Kim, Mariya Popova, Stephen Capuzzi, Jianyang Zeng, Kristen Dang, Gregory Koytiger, Jaewoo Kang, Carrow I. Wells, Timothy M. Willson, The IDG-DREAM Drug-Kinase Binding Prediction Challenge Consortium, Tudor I. Oprea, Avner Schlessinger, David H. Drewry, Gustavo Stolovitzky, Krister Wennerberg, Justin Guinney, Tero Aittokallio
bioRxiv 2019.12.31.891812; doi: https://doi.org/10.1101/2019.12.31.891812
Crowdsourced mapping extends the target space of kinase inhibitors
Anna Cichonska, Balaguru Ravikumar, Robert J Allaway, Sungjoon Park, Fangping Wan, Olexandr Isayev, Shuya Li, Michael Mason, Andrew Lamb, Ziaurrehman Tanoli, Minji Jeon, Sunkyu Kim, Mariya Popova, Stephen Capuzzi, Jianyang Zeng, Kristen Dang, Gregory Koytiger, Jaewoo Kang, Carrow I. Wells, Timothy M. Willson, The IDG-DREAM Drug-Kinase Binding Prediction Challenge Consortium, Tudor I. Oprea, Avner Schlessinger, David H. Drewry, Gustavo Stolovitzky, Krister Wennerberg, Justin Guinney, Tero Aittokallio
bioRxiv 2019.12.31.891812; doi: https://doi.org/10.1101/2019.12.31.891812
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