1Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, OX3 7LF, UK
2Wellcome Centre for Human Genetics, University of Oxford, Oxford, OX3 7BN, UK
3NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford, OX3 9DU, UK
6Program in Medical and Population Genetics, Broad Institute, Cambridge, 02142, Massachusetts, USA
7Nuffield Department of Women’s and Reproductive Health, University of Oxford, Oxford, OX3 9DU, UK
