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A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity
Elaine Thai, Giulia Costa, Anna Weyrich, View ORCID ProfileRajagopal Murugan, View ORCID ProfileDavid Oyen, Katherine Prieto, Alexandre Bosch, View ORCID ProfileAngelo Valleriani, Nicholas C. Wu, Tossapol Pholcharee, View ORCID ProfileStephen W. Scally, Ian A. Wilson, View ORCID ProfileHedda Wardemann, Jean-Philippe Julien, View ORCID ProfileElena A. Levashina
doi: https://doi.org/10.1101/2020.01.13.904425
Elaine Thai
1Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, ON, M5G 1X8, Canada
2Department of Biochemistry, University of Toronto, ON, M5G 0A4, Canada
Giulia Costa
3Vector Biology Unit, Max Planck Institute for Infection Biology, Berlin 10117, Germany
Anna Weyrich
3Vector Biology Unit, Max Planck Institute for Infection Biology, Berlin 10117, Germany
Rajagopal Murugan
4B Cell Immunology, German Cancer Research Institute (DKFZ), Heidelberg 69120, Germany
David Oyen
5Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, 92037, United States of America
Katherine Prieto
2Department of Biochemistry, University of Toronto, ON, M5G 0A4, Canada
Alexandre Bosch
2Department of Biochemistry, University of Toronto, ON, M5G 0A4, Canada
Angelo Valleriani
3Vector Biology Unit, Max Planck Institute for Infection Biology, Berlin 10117, Germany
6Department of Theory and Biosystems, Max Planck Institute of Colloids and Interfaces, Potsdam 14476, Germany
Nicholas C. Wu
5Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, 92037, United States of America
Tossapol Pholcharee
5Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, 92037, United States of America
Stephen W. Scally
1Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, ON, M5G 1X8, Canada
Ian A. Wilson
5Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA, 92037, United States of America
7The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA, 92037, United States of America
Hedda Wardemann
4B Cell Immunology, German Cancer Research Institute (DKFZ), Heidelberg 69120, Germany
Jean-Philippe Julien
1Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, ON, M5G 1X8, Canada
2Department of Biochemistry, University of Toronto, ON, M5G 0A4, Canada
8Department of Immunology, University of Toronto, ON, M5G 0A4, Canada
Elena A. Levashina
3Vector Biology Unit, Max Planck Institute for Infection Biology, Berlin 10117, Germany
Article usage
Posted January 14, 2020.
A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity
Elaine Thai, Giulia Costa, Anna Weyrich, Rajagopal Murugan, David Oyen, Katherine Prieto, Alexandre Bosch, Angelo Valleriani, Nicholas C. Wu, Tossapol Pholcharee, Stephen W. Scally, Ian A. Wilson, Hedda Wardemann, Jean-Philippe Julien, Elena A. Levashina
bioRxiv 2020.01.13.904425; doi: https://doi.org/10.1101/2020.01.13.904425
A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity
Elaine Thai, Giulia Costa, Anna Weyrich, Rajagopal Murugan, David Oyen, Katherine Prieto, Alexandre Bosch, Angelo Valleriani, Nicholas C. Wu, Tossapol Pholcharee, Stephen W. Scally, Ian A. Wilson, Hedda Wardemann, Jean-Philippe Julien, Elena A. Levashina
bioRxiv 2020.01.13.904425; doi: https://doi.org/10.1101/2020.01.13.904425
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