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Cell-type specific effects of genetic variation on chromatin accessibility during human neuronal differentiation
View ORCID ProfileDan Liang, Angela L. Elwell, Nil Aygün, Michael J. Lafferty, Oleh Krupa, Kerry E. Cheek, Kenan P. Courtney, Marianna Yusupova, Melanie E. Garrett, Allison Ashley-Koch, Gregory E. Crawford, Michael I. Love, Luis de la Torre-Ubieta, Daniel H. Geschwind, View ORCID ProfileJason L. Stein
doi: https://doi.org/10.1101/2020.01.13.904862
Dan Liang
1Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
2UNC Neuroscience Center University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Angela L. Elwell
1Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
2UNC Neuroscience Center University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Nil Aygün
1Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
2UNC Neuroscience Center University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Michael J. Lafferty
1Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
2UNC Neuroscience Center University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Oleh Krupa
1Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
2UNC Neuroscience Center University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Kerry E. Cheek
1Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
2UNC Neuroscience Center University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Kenan P. Courtney
1Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
2UNC Neuroscience Center University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Marianna Yusupova
3Neurogenetics Program, Department of Neurology, David Geffen School of Medicine University of California, Los Angeles, Los Angeles, CA 90095, USA
4Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine University of California, Los Angeles, Los Angeles, CA 90095, USA
5Department of Human Genetics, David Geffen School of Medicine University of California, Los Angeles, Los Angeles, CA 90095, USA
Melanie E. Garrett
6Duke Molecular Physiology Institute, Duke University, Durham, NC 27701, USA
Allison Ashley-Koch
6Duke Molecular Physiology Institute, Duke University, Durham, NC 27701, USA
7Department of Medicine, Duke University, Durham, NC 27708, USA
Gregory E. Crawford
8Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA
9Department of Pediatrics, Division of Medical Genetics, Duke University, Durham, NC 27708, USA
Michael I. Love
1Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
10Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Luis de la Torre-Ubieta
3Neurogenetics Program, Department of Neurology, David Geffen School of Medicine University of California, Los Angeles, Los Angeles, CA 90095, USA
4Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine University of California, Los Angeles, Los Angeles, CA 90095, USA
5Department of Human Genetics, David Geffen School of Medicine University of California, Los Angeles, Los Angeles, CA 90095, USA
11Department of Psychiatry and Biobehavioral Sciences, Semel Institute, David Geffen School of Medicine University of California, Los Angeles, Los Angeles, CA 90095, USA
Daniel H. Geschwind
3Neurogenetics Program, Department of Neurology, David Geffen School of Medicine University of California, Los Angeles, Los Angeles, CA 90095, USA
4Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine University of California, Los Angeles, Los Angeles, CA 90095, USA
5Department of Human Genetics, David Geffen School of Medicine University of California, Los Angeles, Los Angeles, CA 90095, USA
11Department of Psychiatry and Biobehavioral Sciences, Semel Institute, David Geffen School of Medicine University of California, Los Angeles, Los Angeles, CA 90095, USA
Jason L. Stein
1Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
2UNC Neuroscience Center University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Posted January 14, 2020.
Cell-type specific effects of genetic variation on chromatin accessibility during human neuronal differentiation
Dan Liang, Angela L. Elwell, Nil Aygün, Michael J. Lafferty, Oleh Krupa, Kerry E. Cheek, Kenan P. Courtney, Marianna Yusupova, Melanie E. Garrett, Allison Ashley-Koch, Gregory E. Crawford, Michael I. Love, Luis de la Torre-Ubieta, Daniel H. Geschwind, Jason L. Stein
bioRxiv 2020.01.13.904862; doi: https://doi.org/10.1101/2020.01.13.904862
Cell-type specific effects of genetic variation on chromatin accessibility during human neuronal differentiation
Dan Liang, Angela L. Elwell, Nil Aygün, Michael J. Lafferty, Oleh Krupa, Kerry E. Cheek, Kenan P. Courtney, Marianna Yusupova, Melanie E. Garrett, Allison Ashley-Koch, Gregory E. Crawford, Michael I. Love, Luis de la Torre-Ubieta, Daniel H. Geschwind, Jason L. Stein
bioRxiv 2020.01.13.904862; doi: https://doi.org/10.1101/2020.01.13.904862
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