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Why most transporter mutations that cause antibiotic resistance are to efflux pumps rather than to import transporters
View ORCID ProfilePedro Mendes, View ORCID ProfileEnrico Girardi, View ORCID ProfileGiulio Superti-Furga, View ORCID ProfileDouglas B. Kell
doi: https://doi.org/10.1101/2020.01.16.909507
Pedro Mendes
1Center for Quantitative Medicine and Department of Cell Biology, University of Connecticut School of Medicine, 263 Farmington Avenue, Farmington, CT 06030-6033, USA
Enrico Girardi
2CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, A-1090 Vienna, Austria
Giulio Superti-Furga
2CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, A-1090 Vienna, Austria
3Center for Physiology and Pharmacology, Medical University of Vienna, 1090, Vienna, Austria
Douglas B. Kell
4Department of Biochemistry, Institute of Integrative Biology, University of Liverpool, Crown St, Liverpool L69 7ZB, UK
5The Novo Nordisk Foundation Center for Biosustainability, Technical University of Denmark, Kemitorvet 200, 2800 Kgs Lyngby, Denmark
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Posted January 17, 2020.
Why most transporter mutations that cause antibiotic resistance are to efflux pumps rather than to import transporters
Pedro Mendes, Enrico Girardi, Giulio Superti-Furga, Douglas B. Kell
bioRxiv 2020.01.16.909507; doi: https://doi.org/10.1101/2020.01.16.909507
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