High-throughput screens of PAM-flexible Cas9 variants for gene knock-out and transcriptional modulation

Mateusz Legut; Zharko Daniloski; Xinhe Xue; Dayna McKenzie; Xinyi Guo; Hans-Hermann Wessels; Neville E. Sanjana

doi:10.1101/2020.01.22.916064

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High-throughput screens of PAM-flexible Cas9 variants for gene knock-out and transcriptional modulation

View ORCID ProfileMateusz Legut, View ORCID ProfileZharko Daniloski, Xinhe Xue, Dayna McKenzie, Xinyi Guo, View ORCID ProfileHans-Hermann Wessels, View ORCID ProfileNeville E. Sanjana

doi: https://doi.org/10.1101/2020.01.22.916064

Mateusz Legut

1New York Genome Center, New York, NY, USA

2Department of Biology, New York University, New York, NY, USA

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ORCID record for Mateusz Legut

Zharko Daniloski

1New York Genome Center, New York, NY, USA

2Department of Biology, New York University, New York, NY, USA

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ORCID record for Zharko Daniloski

Xinhe Xue

1New York Genome Center, New York, NY, USA

2Department of Biology, New York University, New York, NY, USA

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Dayna McKenzie

1New York Genome Center, New York, NY, USA

2Department of Biology, New York University, New York, NY, USA

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Xinyi Guo

1New York Genome Center, New York, NY, USA

2Department of Biology, New York University, New York, NY, USA

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Hans-Hermann Wessels

1New York Genome Center, New York, NY, USA

2Department of Biology, New York University, New York, NY, USA

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ORCID record for Hans-Hermann Wessels

Neville E. Sanjana

1New York Genome Center, New York, NY, USA

2Department of Biology, New York University, New York, NY, USA

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ORCID record for Neville E. Sanjana
For correspondence: neville@sanjanalab.org

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Posted January 23, 2020.

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High-throughput screens of PAM-flexible Cas9 variants for gene knock-out and transcriptional modulation

Mateusz Legut, Zharko Daniloski, Xinhe Xue, Dayna McKenzie, Xinyi Guo, Hans-Hermann Wessels, Neville E. Sanjana

bioRxiv 2020.01.22.916064; doi: https://doi.org/10.1101/2020.01.22.916064

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High-throughput screens of PAM-flexible Cas9 variants for gene knock-out and transcriptional modulation

Mateusz Legut, Zharko Daniloski, Xinhe Xue, Dayna McKenzie, Xinyi Guo, Hans-Hermann Wessels, Neville E. Sanjana

bioRxiv 2020.01.22.916064; doi: https://doi.org/10.1101/2020.01.22.916064

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