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A mysterious 80 nm amoeba virus with a near-complete “ORFan genome” challenges the classification of DNA viruses

Paulo V. M. Boratto, Graziele P. Oliveira, Talita B. Machado, Ana Cláudia S. P. Andrade, Jean-Pierre Baudoin, Thomas Klose, Frederik Schulz, Saïd Azza, Philippe Decloquement, Eric Chabrière, Philippe Colson, Anthony Levasseur, Bernard La Scola, Jônatas S. Abrahão
doi: https://doi.org/10.1101/2020.01.28.923185
Paulo V. M. Boratto
1Laboratório de Vírus, Instituto de Ciências Biológicas, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil
2Microbes, Evolution, Phylogeny and Infection (MEPHI), Aix-Marseille Université UM63, Institut de Recherche pour le Développement IRD 198, Assistance Publique – Hôpitaux de Marseille (AP-HM), Marseille, France
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Graziele P. Oliveira
1Laboratório de Vírus, Instituto de Ciências Biológicas, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil
2Microbes, Evolution, Phylogeny and Infection (MEPHI), Aix-Marseille Université UM63, Institut de Recherche pour le Développement IRD 198, Assistance Publique – Hôpitaux de Marseille (AP-HM), Marseille, France
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Talita B. Machado
1Laboratório de Vírus, Instituto de Ciências Biológicas, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil
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Ana Cláudia S. P. Andrade
1Laboratório de Vírus, Instituto de Ciências Biológicas, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil
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Jean-Pierre Baudoin
2Microbes, Evolution, Phylogeny and Infection (MEPHI), Aix-Marseille Université UM63, Institut de Recherche pour le Développement IRD 198, Assistance Publique – Hôpitaux de Marseille (AP-HM), Marseille, France
3Institut Hospitalo-Universitaire (IHU)-Méditerranée Infection, Marseille, France
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Thomas Klose
4Purdue University, 240 S Martin Jischke Dr, West Lafayette, IN 47907 USA
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Frederik Schulz
5DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA
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Saïd Azza
2Microbes, Evolution, Phylogeny and Infection (MEPHI), Aix-Marseille Université UM63, Institut de Recherche pour le Développement IRD 198, Assistance Publique – Hôpitaux de Marseille (AP-HM), Marseille, France
3Institut Hospitalo-Universitaire (IHU)-Méditerranée Infection, Marseille, France
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Philippe Decloquement
2Microbes, Evolution, Phylogeny and Infection (MEPHI), Aix-Marseille Université UM63, Institut de Recherche pour le Développement IRD 198, Assistance Publique – Hôpitaux de Marseille (AP-HM), Marseille, France
3Institut Hospitalo-Universitaire (IHU)-Méditerranée Infection, Marseille, France
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Eric Chabrière
2Microbes, Evolution, Phylogeny and Infection (MEPHI), Aix-Marseille Université UM63, Institut de Recherche pour le Développement IRD 198, Assistance Publique – Hôpitaux de Marseille (AP-HM), Marseille, France
3Institut Hospitalo-Universitaire (IHU)-Méditerranée Infection, Marseille, France
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Philippe Colson
2Microbes, Evolution, Phylogeny and Infection (MEPHI), Aix-Marseille Université UM63, Institut de Recherche pour le Développement IRD 198, Assistance Publique – Hôpitaux de Marseille (AP-HM), Marseille, France
3Institut Hospitalo-Universitaire (IHU)-Méditerranée Infection, Marseille, France
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Anthony Levasseur
2Microbes, Evolution, Phylogeny and Infection (MEPHI), Aix-Marseille Université UM63, Institut de Recherche pour le Développement IRD 198, Assistance Publique – Hôpitaux de Marseille (AP-HM), Marseille, France
3Institut Hospitalo-Universitaire (IHU)-Méditerranée Infection, Marseille, France
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Bernard La Scola
2Microbes, Evolution, Phylogeny and Infection (MEPHI), Aix-Marseille Université UM63, Institut de Recherche pour le Développement IRD 198, Assistance Publique – Hôpitaux de Marseille (AP-HM), Marseille, France
3Institut Hospitalo-Universitaire (IHU)-Méditerranée Infection, Marseille, France
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  • For correspondence: bernard.la-scola@univ-amu.fr jonatas.abrahao@gmail.com
Jônatas S. Abrahão
1Laboratório de Vírus, Instituto de Ciências Biológicas, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil
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  • For correspondence: bernard.la-scola@univ-amu.fr jonatas.abrahao@gmail.com
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Article Information

doi 
https://doi.org/10.1101/2020.01.28.923185
History 
  • January 28, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Paulo V. M. Boratto1,2,¥,
  2. Graziele P. Oliveira1,2,¥,
  3. Talita B. Machado1,
  4. Ana Cláudia S. P. Andrade1,
  5. Jean-Pierre Baudoin2,3,
  6. Thomas Klose4,
  7. Frederik Schulz5,
  8. Saïd Azza2,3,
  9. Philippe Decloquement2,3,
  10. Eric Chabrière2,3,
  11. Philippe Colson2,3,
  12. Anthony Levasseur2,3,
  13. Bernard La Scola2,3,* and
  14. Jônatas S. Abrahão1,*
  1. 1Laboratório de Vírus, Instituto de Ciências Biológicas, Departamento de Microbiologia, Universidade Federal de Minas Gerais, Belo Horizonte, MG, 31270-901, Brazil
  2. 2Microbes, Evolution, Phylogeny and Infection (MEPHI), Aix-Marseille Université UM63, Institut de Recherche pour le Développement IRD 198, Assistance Publique – Hôpitaux de Marseille (AP-HM), Marseille, France
  3. 3Institut Hospitalo-Universitaire (IHU)-Méditerranée Infection, Marseille, France
  4. 4Purdue University, 240 S Martin Jischke Dr, West Lafayette, IN 47907 USA
  5. 5DOE Joint Genome Institute, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA
  1. ↵*Corresponding authors: bernard.la-scola{at}univ-amu.fr and jonatas.abrahao{at}gmail.com
  1. ↵¥ Contributed equally to this work

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A mysterious 80 nm amoeba virus with a near-complete “ORFan genome” challenges the classification of DNA viruses
Paulo V. M. Boratto, Graziele P. Oliveira, Talita B. Machado, Ana Cláudia S. P. Andrade, Jean-Pierre Baudoin, Thomas Klose, Frederik Schulz, Saïd Azza, Philippe Decloquement, Eric Chabrière, Philippe Colson, Anthony Levasseur, Bernard La Scola, Jônatas S. Abrahão
bioRxiv 2020.01.28.923185; doi: https://doi.org/10.1101/2020.01.28.923185
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A mysterious 80 nm amoeba virus with a near-complete “ORFan genome” challenges the classification of DNA viruses
Paulo V. M. Boratto, Graziele P. Oliveira, Talita B. Machado, Ana Cláudia S. P. Andrade, Jean-Pierre Baudoin, Thomas Klose, Frederik Schulz, Saïd Azza, Philippe Decloquement, Eric Chabrière, Philippe Colson, Anthony Levasseur, Bernard La Scola, Jônatas S. Abrahão
bioRxiv 2020.01.28.923185; doi: https://doi.org/10.1101/2020.01.28.923185

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