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The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells

View ORCID ProfileMarkus Hoffmann, Hannah Kleine-Weber, View ORCID ProfileNadine Krüger, View ORCID ProfileMarcel Müller, Christian Drosten, View ORCID ProfileStefan Pöhlmann
doi: https://doi.org/10.1101/2020.01.31.929042
Markus Hoffmann
1Infection Biology Unit, German Primate Center – Leibniz Institute for Primate Research, Göttingen, Germany
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  • ORCID record for Markus Hoffmann
  • For correspondence: mhoffmann@dpz.eu spoehlmann@dpz.eu
Hannah Kleine-Weber
1Infection Biology Unit, German Primate Center – Leibniz Institute for Primate Research, Göttingen, Germany
2Faculty of Biology and Psychology, University Göttingen, Göttingen, Germany
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Nadine Krüger
3Institute of Virology, University of Veterinary Medicine Hannover, Hannover, Germany
4Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine Hannover, Hannover, Germany
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  • ORCID record for Nadine Krüger
Marcel Müller
5German Centre for Infection Research, associated partner Charité, Berlin, Germany
6Martsinovsky Institute of Medical Parasitology, Tropical and Vector Borne Diseases, Sechenov University, Moscow, Russia
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Christian Drosten
5German Centre for Infection Research, associated partner Charité, Berlin, Germany
6Martsinovsky Institute of Medical Parasitology, Tropical and Vector Borne Diseases, Sechenov University, Moscow, Russia
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Stefan Pöhlmann
1Infection Biology Unit, German Primate Center – Leibniz Institute for Primate Research, Göttingen, Germany
2Faculty of Biology and Psychology, University Göttingen, Göttingen, Germany
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  • For correspondence: mhoffmann@dpz.eu spoehlmann@dpz.eu
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Posted January 31, 2020.
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The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells
Markus Hoffmann, Hannah Kleine-Weber, Nadine Krüger, Marcel Müller, Christian Drosten, Stefan Pöhlmann
bioRxiv 2020.01.31.929042; doi: https://doi.org/10.1101/2020.01.31.929042
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The novel coronavirus 2019 (2019-nCoV) uses the SARS-coronavirus receptor ACE2 and the cellular protease TMPRSS2 for entry into target cells
Markus Hoffmann, Hannah Kleine-Weber, Nadine Krüger, Marcel Müller, Christian Drosten, Stefan Pöhlmann
bioRxiv 2020.01.31.929042; doi: https://doi.org/10.1101/2020.01.31.929042

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