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Targeting STAT3 signalling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer
View ORCID ProfileBruno M. Simões, Angélica Santiago-Gómez, Chiara Chiodo, Tiago Moreira, Daniel Conole, Scott Lovell, Denis Alferez, Rachel Eyre, Katherine Spence, Aida Sarmiento-Castro, Bertram Kohler, Marilena Lanzino, Sebastiano Andò, Elisabetta Marangoni, Andrew H. Sims, View ORCID ProfileEdward Tate, Sacha J. Howell, View ORCID ProfileRobert B. Clarke
doi: https://doi.org/10.1101/2020.02.03.932194
Bruno M. Simões
1Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health University of Manchester, Manchester, UK
Angélica Santiago-Gómez
1Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health University of Manchester, Manchester, UK
Chiara Chiodo
2Department of Pharmacy, University of Calabria, Arcavacata di Rende, Italy
Tiago Moreira
1Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health University of Manchester, Manchester, UK
Daniel Conole
3Molecular Sciences Research Hub, Imperial College London, UK
Scott Lovell
3Molecular Sciences Research Hub, Imperial College London, UK
Denis Alferez
1Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health University of Manchester, Manchester, UK
Rachel Eyre
1Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health University of Manchester, Manchester, UK
Katherine Spence
1Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health University of Manchester, Manchester, UK
Aida Sarmiento-Castro
1Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health University of Manchester, Manchester, UK
Bertram Kohler
1Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health University of Manchester, Manchester, UK
Marilena Lanzino
2Department of Pharmacy, University of Calabria, Arcavacata di Rende, Italy
Sebastiano Andò
2Department of Pharmacy, University of Calabria, Arcavacata di Rende, Italy
Elisabetta Marangoni
4Laboratoire d’investigation préclinique, Institut Curie, Paris, France
Andrew H. Sims
5Applied Bioinformatics of Cancer Group, University of Edinburgh Cancer Research UK Centre, Edinburgh, UK
Edward Tate
3Molecular Sciences Research Hub, Imperial College London, UK
Sacha J. Howell
1Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health University of Manchester, Manchester, UK
6Dept. of Medical Oncology, The Christie NHS Foundation Trust, Manchester, UK
Robert B. Clarke
1Manchester Breast Centre, Division of Cancer Sciences, Faculty of Biology, Medicine and Health University of Manchester, Manchester, UK
Article usage
Posted February 04, 2020.
Targeting STAT3 signalling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer
Bruno M. Simões, Angélica Santiago-Gómez, Chiara Chiodo, Tiago Moreira, Daniel Conole, Scott Lovell, Denis Alferez, Rachel Eyre, Katherine Spence, Aida Sarmiento-Castro, Bertram Kohler, Marilena Lanzino, Sebastiano Andò, Elisabetta Marangoni, Andrew H. Sims, Edward Tate, Sacha J. Howell, Robert B. Clarke
bioRxiv 2020.02.03.932194; doi: https://doi.org/10.1101/2020.02.03.932194
Targeting STAT3 signalling using stabilised sulforaphane (SFX-01) inhibits endocrine resistant stem-like cells in ER-positive breast cancer
Bruno M. Simões, Angélica Santiago-Gómez, Chiara Chiodo, Tiago Moreira, Daniel Conole, Scott Lovell, Denis Alferez, Rachel Eyre, Katherine Spence, Aida Sarmiento-Castro, Bertram Kohler, Marilena Lanzino, Sebastiano Andò, Elisabetta Marangoni, Andrew H. Sims, Edward Tate, Sacha J. Howell, Robert B. Clarke
bioRxiv 2020.02.03.932194; doi: https://doi.org/10.1101/2020.02.03.932194
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