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Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates
View ORCID ProfileChristopher A. Cottrell, View ORCID ProfileJelle van Schooten, View ORCID ProfileCharles A. Bowman, Meng Yuan, David Oyen, View ORCID ProfileMia Shin, Robert Morpurgo, Patricia van der Woude, Marielle van Breemen, View ORCID ProfileJonathan L. Torres, Raj Patel, Justin Gross, View ORCID ProfileLeigh M. Sewall, View ORCID ProfileJeffrey Copps, View ORCID ProfileGabriel Ozorowski, View ORCID ProfileBartek Nogal, View ORCID ProfileDevin Sok, Eva G. Rakasz, Celia Labranche, Vladimir Vigdorovich, Scott Christley, Diane G. Carnathan, View ORCID ProfileD. Noah Sather, View ORCID ProfileDavid Montefiori, View ORCID ProfileGuido Silvestri, View ORCID ProfileDennis R. Burton, John P. Moore, Ian A. Wilson, View ORCID ProfileRogier W. Sanders, View ORCID ProfileAndrew B. Ward, View ORCID ProfileMarit J. van Gils
doi: https://doi.org/10.1101/2020.02.05.936096
Christopher A. Cottrell
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
2IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA
3Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA
Jelle van Schooten
4Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
Charles A. Bowman
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
Meng Yuan
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
David Oyen
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
Mia Shin
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
Robert Morpurgo
4Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
Patricia van der Woude
4Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
Marielle van Breemen
4Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
Jonathan L. Torres
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
Raj Patel
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
Justin Gross
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
Leigh M. Sewall
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
Jeffrey Copps
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
Gabriel Ozorowski
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
2IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA
3Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA
Bartek Nogal
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
2IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA
3Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA
Devin Sok
2IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA
3Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA
5Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA
Eva G. Rakasz
6Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI 53715, USA
Celia Labranche
7Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
Vladimir Vigdorovich
12Center for Global Infectious Disease Research, Seattle Children’s Research Institute, Seattle, WA 98109, USA
Scott Christley
13Department of Population and Data Sciences, UT Southwestern Medical Center, Dallas, TX 75390, USA
Diane G. Carnathan
3Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA
14Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA
D. Noah Sather
12Center for Global Infectious Disease Research, Seattle Children’s Research Institute, Seattle, WA 98109, USA
David Montefiori
7Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
8Duke Human Vaccine Institute, Duke University Medical Center, Durham, NC 27710, USA
Guido Silvestri
3Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA
14Yerkes National Primate Research Center, Emory University, Atlanta, GA 30322, USA
Dennis R. Burton
2IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA
3Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA
5Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA
9The Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA
John P. Moore
10Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA
Ian A. Wilson
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
2IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA
3Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA
11The Skaggs Institute for Chemical Biology, The Scripps Institute, La Jolla, CA 92037, USA
Rogier W. Sanders
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
10Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10021, USA
Andrew B. Ward
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
2IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA
3Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037, USA
Marit J. van Gils
4Department of Medical Microbiology, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
Posted March 02, 2020.
Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates
Christopher A. Cottrell, Jelle van Schooten, Charles A. Bowman, Meng Yuan, David Oyen, Mia Shin, Robert Morpurgo, Patricia van der Woude, Marielle van Breemen, Jonathan L. Torres, Raj Patel, Justin Gross, Leigh M. Sewall, Jeffrey Copps, Gabriel Ozorowski, Bartek Nogal, Devin Sok, Eva G. Rakasz, Celia Labranche, Vladimir Vigdorovich, Scott Christley, Diane G. Carnathan, D. Noah Sather, David Montefiori, Guido Silvestri, Dennis R. Burton, John P. Moore, Ian A. Wilson, Rogier W. Sanders, Andrew B. Ward, Marit J. van Gils
bioRxiv 2020.02.05.936096; doi: https://doi.org/10.1101/2020.02.05.936096
Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates
Christopher A. Cottrell, Jelle van Schooten, Charles A. Bowman, Meng Yuan, David Oyen, Mia Shin, Robert Morpurgo, Patricia van der Woude, Marielle van Breemen, Jonathan L. Torres, Raj Patel, Justin Gross, Leigh M. Sewall, Jeffrey Copps, Gabriel Ozorowski, Bartek Nogal, Devin Sok, Eva G. Rakasz, Celia Labranche, Vladimir Vigdorovich, Scott Christley, Diane G. Carnathan, D. Noah Sather, David Montefiori, Guido Silvestri, Dennis R. Burton, John P. Moore, Ian A. Wilson, Rogier W. Sanders, Andrew B. Ward, Marit J. van Gils
bioRxiv 2020.02.05.936096; doi: https://doi.org/10.1101/2020.02.05.936096
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