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ContamLD: Estimation of Ancient Nuclear DNA Contamination Using Breakdown of Linkage Disequilibrium
View ORCID ProfileNathan Nakatsuka, Éadaoin Harney, Swapan Mallick, Matthew Mah, Nick Patterson, View ORCID ProfileDavid Reich
doi: https://doi.org/10.1101/2020.02.06.938126
Nathan Nakatsuka
1Department of Genetics, Harvard Medical School, New Research Building, 77 Ave. Louis Pasteur, Boston, MA 02115, USA
2Harvard-MIT Division of Health Sciences and Technology, Harvard Medical School, Boston, MA 02115, USA
3Department of Human Evolutionary Biology, Harvard University, 16 Divinity Ave., Cambridge, MA 02138, USA
Éadaoin Harney
1Department of Genetics, Harvard Medical School, New Research Building, 77 Ave. Louis Pasteur, Boston, MA 02115, USA
3Department of Human Evolutionary Biology, Harvard University, 16 Divinity Ave., Cambridge, MA 02138, USA
4Department of Organismic and Evolutionary Biology, Harvard University, 16 Divinity Ave., Cambridge, MA 02138, USA
Swapan Mallick
1Department of Genetics, Harvard Medical School, New Research Building, 77 Ave. Louis Pasteur, Boston, MA 02115, USA
3Department of Human Evolutionary Biology, Harvard University, 16 Divinity Ave., Cambridge, MA 02138, USA
Matthew Mah
1Department of Genetics, Harvard Medical School, New Research Building, 77 Ave. Louis Pasteur, Boston, MA 02115, USA
3Department of Human Evolutionary Biology, Harvard University, 16 Divinity Ave., Cambridge, MA 02138, USA
Nick Patterson
3Department of Human Evolutionary Biology, Harvard University, 16 Divinity Ave., Cambridge, MA 02138, USA
David Reich
1Department of Genetics, Harvard Medical School, New Research Building, 77 Ave. Louis Pasteur, Boston, MA 02115, USA
3Department of Human Evolutionary Biology, Harvard University, 16 Divinity Ave., Cambridge, MA 02138, USA
5Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA 02141, USA
6Howard Hughes Medical Institute, Harvard Medical School, Boston, MA 02115, USA
Posted February 07, 2020.
ContamLD: Estimation of Ancient Nuclear DNA Contamination Using Breakdown of Linkage Disequilibrium
Nathan Nakatsuka, Éadaoin Harney, Swapan Mallick, Matthew Mah, Nick Patterson, David Reich
bioRxiv 2020.02.06.938126; doi: https://doi.org/10.1101/2020.02.06.938126
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