Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Exploring the coronavirus epidemic using the new WashU Virus Genome Browser

View ORCID ProfileJennifer A. Flynn, View ORCID ProfileDeepak Purushotham, View ORCID ProfileMayank NK Choudhary, View ORCID ProfileXiaoyu Zhuo, View ORCID ProfileChangxu Fan, View ORCID ProfileGavriel Matt, View ORCID ProfileDaofeng Li, View ORCID ProfileTing Wang
doi: https://doi.org/10.1101/2020.02.07.939124
Jennifer A. Flynn
1The Edison Family Center for Genome Sciences & Systems Biology, Department of Genetics, Washington University, 4515 McKinley Avenue, Campus Box 8510, St. Louis, MO 63110, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jennifer A. Flynn
Deepak Purushotham
1The Edison Family Center for Genome Sciences & Systems Biology, Department of Genetics, Washington University, 4515 McKinley Avenue, Campus Box 8510, St. Louis, MO 63110, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Deepak Purushotham
Mayank NK Choudhary
1The Edison Family Center for Genome Sciences & Systems Biology, Department of Genetics, Washington University, 4515 McKinley Avenue, Campus Box 8510, St. Louis, MO 63110, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Mayank NK Choudhary
Xiaoyu Zhuo
1The Edison Family Center for Genome Sciences & Systems Biology, Department of Genetics, Washington University, 4515 McKinley Avenue, Campus Box 8510, St. Louis, MO 63110, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Xiaoyu Zhuo
Changxu Fan
1The Edison Family Center for Genome Sciences & Systems Biology, Department of Genetics, Washington University, 4515 McKinley Avenue, Campus Box 8510, St. Louis, MO 63110, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Changxu Fan
Gavriel Matt
1The Edison Family Center for Genome Sciences & Systems Biology, Department of Genetics, Washington University, 4515 McKinley Avenue, Campus Box 8510, St. Louis, MO 63110, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Gavriel Matt
Daofeng Li
1The Edison Family Center for Genome Sciences & Systems Biology, Department of Genetics, Washington University, 4515 McKinley Avenue, Campus Box 8510, St. Louis, MO 63110, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Daofeng Li
  • For correspondence: dli23@wustl.edu twang@genetics.wustl.edu
Ting Wang
1The Edison Family Center for Genome Sciences & Systems Biology, Department of Genetics, Washington University, 4515 McKinley Avenue, Campus Box 8510, St. Louis, MO 63110, USA
2McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63108, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Ting Wang
  • For correspondence: dli23@wustl.edu twang@genetics.wustl.edu
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading

Abstract

Since its debut in mid-December, 2019, the novel coronavirus (2019-nCoV) has rapidly spread from its origin in Wuhan, China, to several countries across the globe, leading to a global health crisis. As of February 7, 2020, 44 strains of the virus have been sequenced and uploaded to NCBI’s GenBank [1], providing insight into the virus’s evolutionary history and pathogenesis. Here, we present the WashU Virus Genome Browser, a web-based portal for viewing virus genomic data. The browser is home to 16 complete 2019-nCoV genome sequences, together with hundreds of related viral sequences including severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), and Ebola virus. In addition, the browser features unique customizability, supporting user-provided upload of novel viral sequences in various formats. Sequences can be viewed in both a track-based representation as well as a phylogenetic tree-based view, allowing the user to easily compare sequence features across multiple strains. The WashU Virus Genome Browser inherited many features and track types from the WashU Epigenome Browser, and additionally incorporated a new type of SNV track to address the specific needs of viral research. Our Virus Browser portal can be accessed at https://virusgateway.wustl.edu, and documentation is available at https://virusgateway.readthedocs.io/.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Back to top
PreviousNext
Posted February 11, 2020.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Exploring the coronavirus epidemic using the new WashU Virus Genome Browser
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Exploring the coronavirus epidemic using the new WashU Virus Genome Browser
Jennifer A. Flynn, Deepak Purushotham, Mayank NK Choudhary, Xiaoyu Zhuo, Changxu Fan, Gavriel Matt, Daofeng Li, Ting Wang
bioRxiv 2020.02.07.939124; doi: https://doi.org/10.1101/2020.02.07.939124
Digg logo Reddit logo Twitter logo Facebook logo Google logo LinkedIn logo Mendeley logo
Citation Tools
Exploring the coronavirus epidemic using the new WashU Virus Genome Browser
Jennifer A. Flynn, Deepak Purushotham, Mayank NK Choudhary, Xiaoyu Zhuo, Changxu Fan, Gavriel Matt, Daofeng Li, Ting Wang
bioRxiv 2020.02.07.939124; doi: https://doi.org/10.1101/2020.02.07.939124

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Genomics
Subject Areas
All Articles
  • Animal Behavior and Cognition (3689)
  • Biochemistry (7797)
  • Bioengineering (5676)
  • Bioinformatics (21290)
  • Biophysics (10578)
  • Cancer Biology (8176)
  • Cell Biology (11945)
  • Clinical Trials (138)
  • Developmental Biology (6763)
  • Ecology (10401)
  • Epidemiology (2065)
  • Evolutionary Biology (13867)
  • Genetics (9708)
  • Genomics (13073)
  • Immunology (8146)
  • Microbiology (20014)
  • Molecular Biology (7853)
  • Neuroscience (43058)
  • Paleontology (320)
  • Pathology (1279)
  • Pharmacology and Toxicology (2258)
  • Physiology (3353)
  • Plant Biology (7232)
  • Scientific Communication and Education (1312)
  • Synthetic Biology (2006)
  • Systems Biology (5538)
  • Zoology (1128)