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RanBP2-mediated SUMOylation promotes human DNA polymerase lambda nuclear localization and DNA repair

M. Moreno-Oñate, A.M. Herrero-Ruiz, M. García-Dominguez, F. Cortés-Ledesma, J.F. Ruiz
doi: https://doi.org/10.1101/2020.02.14.949644
M. Moreno-Oñate
1Departamento Bioquímica Vegetal y Biología Molecular, Universidad de Sevilla, 41012 Sevilla, Spain
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A.M. Herrero-Ruiz
2Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) Universidad de Sevilla/CSIC/Universidad Pablo Olavide/Junta de Andalucía, 41092 Sevilla, Spain
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M. García-Dominguez
2Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) Universidad de Sevilla/CSIC/Universidad Pablo Olavide/Junta de Andalucía, 41092 Sevilla, Spain
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F. Cortés-Ledesma
2Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) Universidad de Sevilla/CSIC/Universidad Pablo Olavide/Junta de Andalucía, 41092 Sevilla, Spain
3Topology and DNA breaks group, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain
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  • For correspondence: jfruiz@us.es fcortes@cnio.es
J.F. Ruiz
1Departamento Bioquímica Vegetal y Biología Molecular, Universidad de Sevilla, 41012 Sevilla, Spain
2Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) Universidad de Sevilla/CSIC/Universidad Pablo Olavide/Junta de Andalucía, 41092 Sevilla, Spain
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  • For correspondence: jfruiz@us.es fcortes@cnio.es
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Article Information

doi 
https://doi.org/10.1101/2020.02.14.949644
History 
  • February 15, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.

Author Information

  1. M. Moreno-Oñate1,†,
  2. A.M. Herrero-Ruiz2,
  3. M. García-Dominguez2,
  4. F. Cortés-Ledesma2,3,* and
  5. J.F. Ruiz1,2,*
  1. 1Departamento Bioquímica Vegetal y Biología Molecular, Universidad de Sevilla, 41012 Sevilla, Spain
  2. 2Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER) Universidad de Sevilla/CSIC/Universidad Pablo Olavide/Junta de Andalucía, 41092 Sevilla, Spain
  3. 3Topology and DNA breaks group, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain
  1. ↵*To whom correspondence should be addressed: Jose F. Ruiz, PhD. Universidad de Sevilla-Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER). Av. Américo Vespucio s/n, 41092 Sevilla, Spain (E-mail: jfruiz{at}us.es) (Phone: +34 954 468 004), Correspondence may also be addressed to: Felipe Cortes-Ledesma, PhD. Spanish National Cancer Research Centre (CNIO). Melchor Fernandez Almagro 3, 28029 Madrid, Spain (E-mail: fcortes{at}cnio.es) (Phone: +34 917 328 000 ext. 3560)
  • ↵† Present address: Andalusian Center for Developmental Biology, 41013 Sevilla, Spain

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Posted February 15, 2020.
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RanBP2-mediated SUMOylation promotes human DNA polymerase lambda nuclear localization and DNA repair
M. Moreno-Oñate, A.M. Herrero-Ruiz, M. García-Dominguez, F. Cortés-Ledesma, J.F. Ruiz
bioRxiv 2020.02.14.949644; doi: https://doi.org/10.1101/2020.02.14.949644
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RanBP2-mediated SUMOylation promotes human DNA polymerase lambda nuclear localization and DNA repair
M. Moreno-Oñate, A.M. Herrero-Ruiz, M. García-Dominguez, F. Cortés-Ledesma, J.F. Ruiz
bioRxiv 2020.02.14.949644; doi: https://doi.org/10.1101/2020.02.14.949644

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