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Fe(III) heme sets an activation threshold for processing distinct groups of pri-miRNAs in mammalian cells

Sara H. Weitz, Jen Quick-Cleveland, Jose P. Jacob, Ian Barr, Rachel Senturia, Kikuye Koyano, Xinshu Xiao, Shimon Weiss, Feng Guo
doi: https://doi.org/10.1101/2020.02.18.955294
Sara H. Weitz
1Interdepartmental Program in Molecular, Cellular, and Integrative Physiology, University of California, Los Angeles, California, 90095
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Jen Quick-Cleveland
2Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, 90095
8Department of Molecular Cell & Developmental Biology, University of California Santa Cruz, Santa Cruz, CA 95064
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Jose P. Jacob
2Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, 90095
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Ian Barr
2Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, 90095
9Dominican University of California, San Rafael, CA 94901
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Rachel Senturia
2Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, 90095
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Kikuye Koyano
3Bioinformatics Interdepartmental Program, University of California, Los Angeles, California, 90095
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Xinshu Xiao
3Bioinformatics Interdepartmental Program, University of California, Los Angeles, California, 90095
4Department of Integrative Biology and Physiology, University of California, Los Angeles, California, 90095
7Molecular Biology Institute, University of California, Los Angeles, California, 90095
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Shimon Weiss
5Department of Chemistry and Biochemistry, University of California, Los Angeles, California, 90095
6Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, California, 90095
7Molecular Biology Institute, University of California, Los Angeles, California, 90095
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Feng Guo
2Department of Biological Chemistry, David Geffen School of Medicine, University of California, Los Angeles, California, 90095
7Molecular Biology Institute, University of California, Los Angeles, California, 90095
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  • For correspondence: fguo@mbi.ucla.edu
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Posted February 19, 2020.
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Fe(III) heme sets an activation threshold for processing distinct groups of pri-miRNAs in mammalian cells
Sara H. Weitz, Jen Quick-Cleveland, Jose P. Jacob, Ian Barr, Rachel Senturia, Kikuye Koyano, Xinshu Xiao, Shimon Weiss, Feng Guo
bioRxiv 2020.02.18.955294; doi: https://doi.org/10.1101/2020.02.18.955294
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Fe(III) heme sets an activation threshold for processing distinct groups of pri-miRNAs in mammalian cells
Sara H. Weitz, Jen Quick-Cleveland, Jose P. Jacob, Ian Barr, Rachel Senturia, Kikuye Koyano, Xinshu Xiao, Shimon Weiss, Feng Guo
bioRxiv 2020.02.18.955294; doi: https://doi.org/10.1101/2020.02.18.955294

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