Article Information
History
- February 24, 2020.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.
Author Information
- Margot Brandt1,2,3,
- Sarah Kim-Hellmuth1,2,4,5,
- Marcello Ziosi1,
- Alper Gokden1,
- Aaron Wolman1,
- Nora Lam1,6,
- Yocelyn Recinos1,2,3,
- Veit Hornung7,
- Johannes Schumacher8 and
- Tuuli Lappalainen1,2,#
- 1New York Genome Center, New York, NY, USA
- 2Department of Systems Biology, Columbia University, New York, NY, USA
- 3Integrated Program in Cellular, Molecular, and Biomedical Studies, Columbia University, New York, NY, USA
- 4Statistical Genetics, Max Planck Institute of Psychiatry, Munich, Germany
- 5Dr. von Hauner Children’s Hospital, Department of Pediatrics, University Hospital LMU Munich, Munich, Germany
- 6Program of Pathobiology and Mechanisms of Disease, Columbia University, New York, NY, USA
- 7Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany
- 8Center for Human Genetics, University Hospital Marburg, Marburg, Germany
- ↵#Corresponding author. Email: tlappalainen{at}nygenome.org; Tel. +1-646 977 7037.
Posted February 24, 2020.
An autoimmune disease risk variant has a trans master regulatory effect mediated by IRF1 under immune stimulation
