Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

An autoimmune disease risk variant has a trans master regulatory effect mediated by IRF1 under immune stimulation

Margot Brandt, Sarah Kim-Hellmuth, Marcello Ziosi, Alper Gokden, Aaron Wolman, Nora Lam, Yocelyn Recinos, Veit Hornung, Johannes Schumacher, View ORCID ProfileTuuli Lappalainen
doi: https://doi.org/10.1101/2020.02.21.959734
Margot Brandt
1New York Genome Center, New York, NY, USA
2Department of Systems Biology, Columbia University, New York, NY, USA
3Integrated Program in Cellular, Molecular, and Biomedical Studies, Columbia University, New York, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sarah Kim-Hellmuth
1New York Genome Center, New York, NY, USA
2Department of Systems Biology, Columbia University, New York, NY, USA
4Statistical Genetics, Max Planck Institute of Psychiatry, Munich, Germany
5Dr. von Hauner Children’s Hospital, Department of Pediatrics, University Hospital LMU Munich, Munich, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marcello Ziosi
1New York Genome Center, New York, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Alper Gokden
1New York Genome Center, New York, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Aaron Wolman
1New York Genome Center, New York, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nora Lam
1New York Genome Center, New York, NY, USA
6Program of Pathobiology and Mechanisms of Disease, Columbia University, New York, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yocelyn Recinos
1New York Genome Center, New York, NY, USA
2Department of Systems Biology, Columbia University, New York, NY, USA
3Integrated Program in Cellular, Molecular, and Biomedical Studies, Columbia University, New York, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Veit Hornung
7Gene Center and Department of Biochemistry, Ludwig-Maximilians-Universität München, Munich, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Johannes Schumacher
8Center for Human Genetics, University Hospital Marburg, Marburg, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tuuli Lappalainen
1New York Genome Center, New York, NY, USA
2Department of Systems Biology, Columbia University, New York, NY, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Tuuli Lappalainen
  • For correspondence: tlappalainen@nygenome.org
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading

Article usage

Article usage: February 2020 to February 2023

AbstractFullPdf
Feb 202016459295
Mar 20202532793
May 20201144937
Jun 202089938
Jul 202036818
Aug 202066614
Sep 2020761628
Oct 202040617
Nov 2020311220
Dec 2020621110
Jan 2021421116
Feb 202130227
Mar 2021553824
Apr 2021471716
May 2021551622
Jun 2021901319
Jul 2021541213
Aug 202136179
Sep 202126414
Oct 202124618
Nov 202127716
Dec 20212031
Jan 20222804
Feb 20221410
Mar 20221442
Apr 20222333
May 202221713
Jun 2022712
Jul 20221403
Aug 20221326
Sep 20221627
Oct 20222323
Nov 20221513
Dec 20221363
Jan 20232257
Feb 2023001
Back to top
PreviousNext
Posted February 24, 2020.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
An autoimmune disease risk variant has a trans master regulatory effect mediated by IRF1 under immune stimulation
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
An autoimmune disease risk variant has a trans master regulatory effect mediated by IRF1 under immune stimulation
Margot Brandt, Sarah Kim-Hellmuth, Marcello Ziosi, Alper Gokden, Aaron Wolman, Nora Lam, Yocelyn Recinos, Veit Hornung, Johannes Schumacher, Tuuli Lappalainen
bioRxiv 2020.02.21.959734; doi: https://doi.org/10.1101/2020.02.21.959734
Digg logo Reddit logo Twitter logo Facebook logo Google logo LinkedIn logo Mendeley logo
Citation Tools
An autoimmune disease risk variant has a trans master regulatory effect mediated by IRF1 under immune stimulation
Margot Brandt, Sarah Kim-Hellmuth, Marcello Ziosi, Alper Gokden, Aaron Wolman, Nora Lam, Yocelyn Recinos, Veit Hornung, Johannes Schumacher, Tuuli Lappalainen
bioRxiv 2020.02.21.959734; doi: https://doi.org/10.1101/2020.02.21.959734

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Genomics
Subject Areas
All Articles
  • Animal Behavior and Cognition (4105)
  • Biochemistry (8807)
  • Bioengineering (6508)
  • Bioinformatics (23446)
  • Biophysics (11783)
  • Cancer Biology (9196)
  • Cell Biology (13307)
  • Clinical Trials (138)
  • Developmental Biology (7428)
  • Ecology (11402)
  • Epidemiology (2066)
  • Evolutionary Biology (15141)
  • Genetics (10429)
  • Genomics (14036)
  • Immunology (9167)
  • Microbiology (22142)
  • Molecular Biology (8802)
  • Neuroscience (47533)
  • Paleontology (350)
  • Pathology (1427)
  • Pharmacology and Toxicology (2489)
  • Physiology (3729)
  • Plant Biology (8076)
  • Scientific Communication and Education (1437)
  • Synthetic Biology (2220)
  • Systems Biology (6036)
  • Zoology (1252)