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Genomic and transcriptomic analyses reveal a tandem amplification unit of 11 genes and mutations of mismatch repair genes in methotrexate-resistant HT-29 cells

View ORCID ProfileAhreum Kim, Jong-Yeon Shin, Jeong-Sun Seo
doi: https://doi.org/10.1101/2020.02.26.965814
Ahreum Kim
1Precision Medicine Center, Seoul National University Bundang Hospital, Seongnamsi 13605, Korea
2Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Republic of Korea
3CHA University School of Medicine, Seongnam, South Korea
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Jong-Yeon Shin
1Precision Medicine Center, Seoul National University Bundang Hospital, Seongnamsi 13605, Korea
4Macrogen Inc., Seoul 08511, Korea
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Jeong-Sun Seo
1Precision Medicine Center, Seoul National University Bundang Hospital, Seongnamsi 13605, Korea
2Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul 03080, Republic of Korea
4Macrogen Inc., Seoul 08511, Korea
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  • For correspondence: jeongsunseo@gmail.com
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Posted February 27, 2020.
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Genomic and transcriptomic analyses reveal a tandem amplification unit of 11 genes and mutations of mismatch repair genes in methotrexate-resistant HT-29 cells
Ahreum Kim, Jong-Yeon Shin, Jeong-Sun Seo
bioRxiv 2020.02.26.965814; doi: https://doi.org/10.1101/2020.02.26.965814
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Genomic and transcriptomic analyses reveal a tandem amplification unit of 11 genes and mutations of mismatch repair genes in methotrexate-resistant HT-29 cells
Ahreum Kim, Jong-Yeon Shin, Jeong-Sun Seo
bioRxiv 2020.02.26.965814; doi: https://doi.org/10.1101/2020.02.26.965814

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