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Population Stratification at the Phenotypic Variance level and Implication for the Analysis of Whole Genome Sequencing Data from Multiple Studies
View ORCID ProfileTamar Sofer, Xiuwen Zheng, Cecelia A. Laurie, Stephanie M. Gogarten, Jennifer A. Brody, Matthew P. Conomos, Joshua C. Bis, Timothy A. Thornton, Adam Szpiro, Jeffrey R. O’Connell, Ethan M. Lange, Yan Gao, L. Adrienne Cupples, Bruce M. Psaty, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Kenneth M. Rice
doi: https://doi.org/10.1101/2020.03.03.973420
Tamar Sofer
1Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, Massachusetts
2Departments of Medicine and of Biostatistics, Harvard University, Boston, Massachusetts
Xiuwen Zheng
3Department of Biostatistics, University of Washington, Seattle, Washington
Cecelia A. Laurie
3Department of Biostatistics, University of Washington, Seattle, Washington
Stephanie M. Gogarten
3Department of Biostatistics, University of Washington, Seattle, Washington
Jennifer A. Brody
4Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, Washington
Matthew P. Conomos
3Department of Biostatistics, University of Washington, Seattle, Washington
Joshua C. Bis
4Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, Washington
Timothy A. Thornton
3Department of Biostatistics, University of Washington, Seattle, Washington
Adam Szpiro
3Department of Biostatistics, University of Washington, Seattle, Washington
Jeffrey R. O’Connell
5Department of Medicine, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland
Ethan M. Lange
6Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado
Yan Gao
8School of Medicine, University Mississippi Medical Center, Jackson, Mississippi
L. Adrienne Cupples
9Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts
10Boston University’s and National Heart, Lung, and Blood Institute’s Framingham Heart Study, Framingham, Massachusetts
Bruce M. Psaty
4Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, and Health Services, University of Washington, Seattle, Washington
11Kaiser Permanente Washington Health Research Institute, Seattle, Washington
Kenneth M. Rice
3Department of Biostatistics, University of Washington, Seattle, Washington
Posted March 05, 2020.
Population Stratification at the Phenotypic Variance level and Implication for the Analysis of Whole Genome Sequencing Data from Multiple Studies
Tamar Sofer, Xiuwen Zheng, Cecelia A. Laurie, Stephanie M. Gogarten, Jennifer A. Brody, Matthew P. Conomos, Joshua C. Bis, Timothy A. Thornton, Adam Szpiro, Jeffrey R. O’Connell, Ethan M. Lange, Yan Gao, L. Adrienne Cupples, Bruce M. Psaty, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Kenneth M. Rice
bioRxiv 2020.03.03.973420; doi: https://doi.org/10.1101/2020.03.03.973420
Population Stratification at the Phenotypic Variance level and Implication for the Analysis of Whole Genome Sequencing Data from Multiple Studies
Tamar Sofer, Xiuwen Zheng, Cecelia A. Laurie, Stephanie M. Gogarten, Jennifer A. Brody, Matthew P. Conomos, Joshua C. Bis, Timothy A. Thornton, Adam Szpiro, Jeffrey R. O’Connell, Ethan M. Lange, Yan Gao, L. Adrienne Cupples, Bruce M. Psaty, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Kenneth M. Rice
bioRxiv 2020.03.03.973420; doi: https://doi.org/10.1101/2020.03.03.973420
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