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Efficient inactivation of SARS-CoV-2 by WHO-recommended hand rub formulations and alcohols

Annika Kratzel, Daniel Todt, Philip V’kovski, Silvio Steiner, Mitra L. Gultom, Tran Thi Nhu Thao, Nadine Ebert, Melle Holwerda, Jörg Steinmann, Daniela Niemeyer, View ORCID ProfileRonald Dijkman, Günter Kampf, Christian Drosten, Eike Steinmann, Volker Thiel, Stephanie Pfaender
doi: https://doi.org/10.1101/2020.03.10.986711
Annika Kratzel
1Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
3Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland
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Daniel Todt
4Department for Molecular & Medical Virology, Ruhr-Universität Bochum, Germany
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Philip V’kovski
1Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
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Silvio Steiner
1Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
3Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland
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Mitra L. Gultom
1Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
3Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland
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Tran Thi Nhu Thao
1Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
3Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland
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Nadine Ebert
1Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
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Melle Holwerda
1Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
3Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland
7Institute for Infectious Diseases, University of Bern, Bern, Switzerland
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Jörg Steinmann
5Institute of Medical Microbiology, University Hospital of Essen, Essen, Germany
6Institute of Clinical Hygiene, Medical Microbiology and Infectiology, General Hospital Nürnberg, Paracelsus Medical University, Nuremberg, Germany
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Daniela Niemeyer
9Institute of Virology, Charité Berlin, Berlin, Germany
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Ronald Dijkman
1Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
7Institute for Infectious Diseases, University of Bern, Bern, Switzerland
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  • ORCID record for Ronald Dijkman
Günter Kampf
8University Medicine Greifswald, Institute for Hygiene and Environmental Medicine, Greifswald, Germany
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Christian Drosten
9Institute of Virology, Charité Berlin, Berlin, Germany
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Eike Steinmann
4Department for Molecular & Medical Virology, Ruhr-Universität Bochum, Germany
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Volker Thiel
1Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
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Stephanie Pfaender
4Department for Molecular & Medical Virology, Ruhr-Universität Bochum, Germany
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  • For correspondence: stephanie.pfaender@ruhr-uni-bochum.de
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Article Information

doi 
https://doi.org/10.1101/2020.03.10.986711
History 
  • March 17, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Annika Kratzel1,2,3,
  2. Daniel Todt4,
  3. Philip V’kovski1,2,
  4. Silvio Steiner1,2,3,
  5. Mitra L. Gultom1,2,3,
  6. Tran Thi Nhu Thao1,2,3,
  7. Nadine Ebert1,2,
  8. Melle Holwerda1,2,3,7,
  9. Jörg Steinmann5,6,
  10. Daniela Niemeyer9,
  11. Ronald Dijkman1,2,7,
  12. Günter Kampf8,
  13. Christian Drosten9,
  14. Eike Steinmann4,
  15. Volker Thiel1,2 and
  16. Stephanie Pfaender4,#
  1. 1Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
  2. 2Department of Infectious Diseases and Pathobiology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
  3. 3Graduate School for Cellular and Biomedical Sciences, University of Bern, Bern, Switzerland
  4. 4Department for Molecular & Medical Virology, Ruhr-Universität Bochum, Germany
  5. 5Institute of Medical Microbiology, University Hospital of Essen, Essen, Germany
  6. 6Institute of Clinical Hygiene, Medical Microbiology and Infectiology, General Hospital Nürnberg, Paracelsus Medical University, Nuremberg, Germany
  7. 7Institute for Infectious Diseases, University of Bern, Bern, Switzerland
  8. 8University Medicine Greifswald, Institute for Hygiene and Environmental Medicine, Greifswald, Germany
  9. 9Institute of Virology, Charité Berlin, Berlin, Germany
  1. ↵#Address for correspondence
    , Prof. Dr. rer. nat. Stephanie Pfänder, Department for Molecular & Medical Virology, Ruhr-Universität Bochum, Universitätsstrasse 150, 44801 Bochum, Germany, Email: stephanie.pfaender{at}ruhr-uni-bochum.de, Phone: +49 234 32 29278
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Efficient inactivation of SARS-CoV-2 by WHO-recommended hand rub formulations and alcohols
Annika Kratzel, Daniel Todt, Philip V’kovski, Silvio Steiner, Mitra L. Gultom, Tran Thi Nhu Thao, Nadine Ebert, Melle Holwerda, Jörg Steinmann, Daniela Niemeyer, Ronald Dijkman, Günter Kampf, Christian Drosten, Eike Steinmann, Volker Thiel, Stephanie Pfaender
bioRxiv 2020.03.10.986711; doi: https://doi.org/10.1101/2020.03.10.986711
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Efficient inactivation of SARS-CoV-2 by WHO-recommended hand rub formulations and alcohols
Annika Kratzel, Daniel Todt, Philip V’kovski, Silvio Steiner, Mitra L. Gultom, Tran Thi Nhu Thao, Nadine Ebert, Melle Holwerda, Jörg Steinmann, Daniela Niemeyer, Ronald Dijkman, Günter Kampf, Christian Drosten, Eike Steinmann, Volker Thiel, Stephanie Pfaender
bioRxiv 2020.03.10.986711; doi: https://doi.org/10.1101/2020.03.10.986711

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