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Angioplasty-induced epigenomic remodeling entails BRD4 and EZH2 hierarchical regulations

Mengxue Zhang, Bowen Wang, Go Urabe, Hatice Gulcin Ozer, Renzhi Han, K. Craig Kent, Lian-Wang Guo
doi: https://doi.org/10.1101/2020.03.12.989640
Mengxue Zhang
1Department of Surgery and Department of Physiology & Cell Biology, College of Medicine; Davis Heart and Lung Research Institute, Wexner Medical Center. The Ohio State University, Columbus, OH 43210, USA
2Cellular and Molecular Pathology graduate program, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705, USA
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Bowen Wang
3Department of Surgery, College of Medicine; Davis Heart and Lung Research Institute, Wexner Medical Center. The Ohio State University, Columbus, OH 43210, USA
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Go Urabe
1Department of Surgery and Department of Physiology & Cell Biology, College of Medicine; Davis Heart and Lung Research Institute, Wexner Medical Center. The Ohio State University, Columbus, OH 43210, USA
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Hatice Gulcin Ozer
4Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
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Renzhi Han
3Department of Surgery, College of Medicine; Davis Heart and Lung Research Institute, Wexner Medical Center. The Ohio State University, Columbus, OH 43210, USA
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K. Craig Kent
3Department of Surgery, College of Medicine; Davis Heart and Lung Research Institute, Wexner Medical Center. The Ohio State University, Columbus, OH 43210, USA
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Lian-Wang Guo
1Department of Surgery and Department of Physiology & Cell Biology, College of Medicine; Davis Heart and Lung Research Institute, Wexner Medical Center. The Ohio State University, Columbus, OH 43210, USA
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  • For correspondence: lianwang.guo@osumc.edu
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Article Information

doi 
https://doi.org/10.1101/2020.03.12.989640
History 
  • March 14, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Mengxue Zhang1,2,¶,
  2. Bowen Wang3,¶,
  3. Go Urabe1,¶,
  4. Hatice Gulcin Ozer4,
  5. Renzhi Han3,
  6. K. Craig Kent3 and
  7. Lian-Wang Guo1,*
  1. 1Department of Surgery and Department of Physiology & Cell Biology, College of Medicine; Davis Heart and Lung Research Institute, Wexner Medical Center. The Ohio State University, Columbus, OH 43210, USA
  2. 2Cellular and Molecular Pathology graduate program, School of Medicine and Public Health, University of Wisconsin, Madison, WI 53705, USA
  3. 3Department of Surgery, College of Medicine; Davis Heart and Lung Research Institute, Wexner Medical Center. The Ohio State University, Columbus, OH 43210, USA
  4. 4Department of Biomedical Informatics, College of Medicine, The Ohio State University, Columbus, OH 43210, USA
  1. ↵*Corresponding author: Lian-Wang Guo, Ph.D., Department of Surgery and Department of Physiology & Cell Biology, The Ohio State University, 473 West 12th Ave, Columbus, OH 43210, USA, Tel: +1 614 292 5276. Email: lianwang.guo{at}osumc.edu
  1. ↵¶ These authors contributed equally to this work.

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Posted March 14, 2020.
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Angioplasty-induced epigenomic remodeling entails BRD4 and EZH2 hierarchical regulations
Mengxue Zhang, Bowen Wang, Go Urabe, Hatice Gulcin Ozer, Renzhi Han, K. Craig Kent, Lian-Wang Guo
bioRxiv 2020.03.12.989640; doi: https://doi.org/10.1101/2020.03.12.989640
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Angioplasty-induced epigenomic remodeling entails BRD4 and EZH2 hierarchical regulations
Mengxue Zhang, Bowen Wang, Go Urabe, Hatice Gulcin Ozer, Renzhi Han, K. Craig Kent, Lian-Wang Guo
bioRxiv 2020.03.12.989640; doi: https://doi.org/10.1101/2020.03.12.989640

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