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Rapidly predicting vancomycin resistance of Enterococcus faecium through MALDI-TOF MS spectrum obtained in real-world clinical microbiology laboratory

Hsin-Yao Wang, Ko-Pei Lu, Chia-Ru Chung, Yi-Ju Tseng, Tzong-Yi Lee, Jorng-Tzong Horng, Tzu-Hao Chang, Min-Hsien Wu, Ting-Wei Lin, Tsui-Ping Liu, Jang-Jih Lu
doi: https://doi.org/10.1101/2020.03.13.990978
Hsin-Yao Wang
1Department of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
2Ph.D. Program in Biomedical Engineering, Chang Gung University, Taoyuan City, Taiwan
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Ko-Pei Lu
3Graduate Program in Biomedical Information, Yuan-Ze University, Taoyuan City, Taiwan
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Chia-Ru Chung
4Department of Computer Science and Information Engineering, National Central University, Taoyuan City, Taiwan
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Yi-Ju Tseng
1Department of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
5Department of Information Management, Chang Gung University, Taoyuan City, Taiwan
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Tzong-Yi Lee
1Department of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
6School of Science and Engineering, The Chinese University of Hong Kong, Shenzhen, China
7Warshel Institute for Computational Biology, The Chinese University of Hong Kong, Shenzhen, China
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Jorng-Tzong Horng
1Department of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
4Department of Computer Science and Information Engineering, National Central University, Taoyuan City, Taiwan
8Department of Bioinformatics and Medical Engineering, Asia University, Taichung City, Taiwan
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Tzu-Hao Chang
9Graduate Institute of Biomedical Informatics, Taipei Medical University, Taipei City, Taiwan
10Clinical Big Data Research Center, Taipei Medical University Hospital, Taipei City, Taiwan
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Min-Hsien Wu
11Graduate Institute of Biomedical Engineering, Chang Gung University, Taoyuan City, Taiwan
12Division of Haematology/Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
13Biosensor Group, Biomedical Engineering Research Center, Chang Gung University, Taoyuan City, Taiwan
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Ting-Wei Lin
1Department of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
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Tsui-Ping Liu
1Department of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
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Jang-Jih Lu
1Department of Laboratory Medicine, Chang Gung Memorial Hospital at Linkou, Taoyuan City, Taiwan
14School of Medicine, Chang Gung University, Taoyuan City, Taiwan
15Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Taoyuan City, Taiwan
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  • For correspondence: mdhsinyaowang@gmail.com
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Posted March 15, 2020.
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Rapidly predicting vancomycin resistance of Enterococcus faecium through MALDI-TOF MS spectrum obtained in real-world clinical microbiology laboratory
Hsin-Yao Wang, Ko-Pei Lu, Chia-Ru Chung, Yi-Ju Tseng, Tzong-Yi Lee, Jorng-Tzong Horng, Tzu-Hao Chang, Min-Hsien Wu, Ting-Wei Lin, Tsui-Ping Liu, Jang-Jih Lu
bioRxiv 2020.03.13.990978; doi: https://doi.org/10.1101/2020.03.13.990978
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Rapidly predicting vancomycin resistance of Enterococcus faecium through MALDI-TOF MS spectrum obtained in real-world clinical microbiology laboratory
Hsin-Yao Wang, Ko-Pei Lu, Chia-Ru Chung, Yi-Ju Tseng, Tzong-Yi Lee, Jorng-Tzong Horng, Tzu-Hao Chang, Min-Hsien Wu, Ting-Wei Lin, Tsui-Ping Liu, Jang-Jih Lu
bioRxiv 2020.03.13.990978; doi: https://doi.org/10.1101/2020.03.13.990978

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