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An emergent clade of SARS-CoV-2 linked to returned travellers from Iran
View ORCID ProfileJohn-Sebastian Eden, Rebecca Rockett, Ian Carter, Hossinur Rahman, Joep de Ligt, James Hadfield, Matthew Storey, Xiaoyun Ren, Rachel Tulloch, Kerri Basile, Jessica Wells, Roy Byun, Nicky Gilroy, Matthew V O’Sullivan, Vitali Sintchenko, Sharon C Chen, Susan Maddocks, Tania C Sorrell, Edward C Holmes, Dominic E Dwyer, Jen Kok, for the 2019-nCoV Study Group
doi: https://doi.org/10.1101/2020.03.15.992818
John-Sebastian Eden
1The University of Sydney, Marie Bashir Institute for Infectious Diseases and Biosecurity, School of Life and Environmental Sciences & School of Medical Sciences, NSW 2006, Australia
2Westmead Institute for Medical Research, Centre for Virus Research & Centre for Infectious Diseases and Microbiology, Westmead, NSW 2145, Australia
Rebecca Rockett
1The University of Sydney, Marie Bashir Institute for Infectious Diseases and Biosecurity, School of Life and Environmental Sciences & School of Medical Sciences, NSW 2006, Australia
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
4Centre for Infectious Diseases and Microbiology – Public Health, Westmead Hospital, Westmead NSW 2145, Australia
Ian Carter
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
Hossinur Rahman
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
Joep de Ligt
5Institute of Environmental Science and Research, Porirua 5240, New Zealand
James Hadfield
6Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
Matthew Storey
5Institute of Environmental Science and Research, Porirua 5240, New Zealand
Xiaoyun Ren
5Institute of Environmental Science and Research, Porirua 5240, New Zealand
Rachel Tulloch
1The University of Sydney, Marie Bashir Institute for Infectious Diseases and Biosecurity, School of Life and Environmental Sciences & School of Medical Sciences, NSW 2006, Australia
2Westmead Institute for Medical Research, Centre for Virus Research & Centre for Infectious Diseases and Microbiology, Westmead, NSW 2145, Australia
Kerri Basile
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
Jessica Wells
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
Roy Byun
7NSW Ministry of Health, North Sydney, NSW 2059, Australia
Nicky Gilroy
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
Matthew V O’Sullivan
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
4Centre for Infectious Diseases and Microbiology – Public Health, Westmead Hospital, Westmead NSW 2145, Australia
Vitali Sintchenko
1The University of Sydney, Marie Bashir Institute for Infectious Diseases and Biosecurity, School of Life and Environmental Sciences & School of Medical Sciences, NSW 2006, Australia
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
4Centre for Infectious Diseases and Microbiology – Public Health, Westmead Hospital, Westmead NSW 2145, Australia
Sharon C Chen
1The University of Sydney, Marie Bashir Institute for Infectious Diseases and Biosecurity, School of Life and Environmental Sciences & School of Medical Sciences, NSW 2006, Australia
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
4Centre for Infectious Diseases and Microbiology – Public Health, Westmead Hospital, Westmead NSW 2145, Australia
Susan Maddocks
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
Tania C Sorrell
1The University of Sydney, Marie Bashir Institute for Infectious Diseases and Biosecurity, School of Life and Environmental Sciences & School of Medical Sciences, NSW 2006, Australia
2Westmead Institute for Medical Research, Centre for Virus Research & Centre for Infectious Diseases and Microbiology, Westmead, NSW 2145, Australia
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
Edward C Holmes
1The University of Sydney, Marie Bashir Institute for Infectious Diseases and Biosecurity, School of Life and Environmental Sciences & School of Medical Sciences, NSW 2006, Australia
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
Dominic E Dwyer
1The University of Sydney, Marie Bashir Institute for Infectious Diseases and Biosecurity, School of Life and Environmental Sciences & School of Medical Sciences, NSW 2006, Australia
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
4Centre for Infectious Diseases and Microbiology – Public Health, Westmead Hospital, Westmead NSW 2145, Australia
Jen Kok
3Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology - Institute of Clinical Pathology and Medical Research, NSW 2145, Australia
4Centre for Infectious Diseases and Microbiology – Public Health, Westmead Hospital, Westmead NSW 2145, Australia
Abstract
The SARS-CoV-2 epidemic has rapidly spread outside China with major outbreaks occurring in Italy, South Korea and Iran. Phylogenetic analyses of whole genome sequencing data identified a distinct SARS-CoV-2 clade linked to travellers returning from Iran to Australia and New Zealand. This study highlights potential viral diversity driving the epidemic in Iran, and underscores the power of rapid genome sequencing and public data sharing to improve the detection and management of emerging infectious diseases.
Copyright
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC 4.0 International license.
Posted March 17, 2020.
An emergent clade of SARS-CoV-2 linked to returned travellers from Iran
John-Sebastian Eden, Rebecca Rockett, Ian Carter, Hossinur Rahman, Joep de Ligt, James Hadfield, Matthew Storey, Xiaoyun Ren, Rachel Tulloch, Kerri Basile, Jessica Wells, Roy Byun, Nicky Gilroy, Matthew V O’Sullivan, Vitali Sintchenko, Sharon C Chen, Susan Maddocks, Tania C Sorrell, Edward C Holmes, Dominic E Dwyer, Jen Kok, for the 2019-nCoV Study Group
bioRxiv 2020.03.15.992818; doi: https://doi.org/10.1101/2020.03.15.992818
An emergent clade of SARS-CoV-2 linked to returned travellers from Iran
John-Sebastian Eden, Rebecca Rockett, Ian Carter, Hossinur Rahman, Joep de Ligt, James Hadfield, Matthew Storey, Xiaoyun Ren, Rachel Tulloch, Kerri Basile, Jessica Wells, Roy Byun, Nicky Gilroy, Matthew V O’Sullivan, Vitali Sintchenko, Sharon C Chen, Susan Maddocks, Tania C Sorrell, Edward C Holmes, Dominic E Dwyer, Jen Kok, for the 2019-nCoV Study Group
bioRxiv 2020.03.15.992818; doi: https://doi.org/10.1101/2020.03.15.992818
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