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SARS-CoV-2 launches a unique transcriptional signature from in vitro, ex vivo, and in vivo systems

Daniel Blanco-Melo, Benjamin E. Nilsson-Payant, Wen-Chun Liu, Rasmus Møller, Maryline Panis, David Sachs, Randy A. Albrecht, Benjamin R. tenOever
doi: https://doi.org/10.1101/2020.03.24.004655
Daniel Blanco-Melo
1Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, USA
2Virus Engineering Center for Therapeutics and Research (VECToR), Icahn School of Medicine at Mount Sinai, New York, USA
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Benjamin E. Nilsson-Payant
1Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, USA
2Virus Engineering Center for Therapeutics and Research (VECToR), Icahn School of Medicine at Mount Sinai, New York, USA
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Wen-Chun Liu
1Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, USA
3Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, USA
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Rasmus Møller
1Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, USA
2Virus Engineering Center for Therapeutics and Research (VECToR), Icahn School of Medicine at Mount Sinai, New York, USA
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Maryline Panis
1Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, USA
2Virus Engineering Center for Therapeutics and Research (VECToR), Icahn School of Medicine at Mount Sinai, New York, USA
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David Sachs
4Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, USA
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Randy A. Albrecht
1Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, USA
3Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, USA
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  • For correspondence: benjamin.tenoever@mssm.edu
Benjamin R. tenOever
1Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, USA
2Virus Engineering Center for Therapeutics and Research (VECToR), Icahn School of Medicine at Mount Sinai, New York, USA
3Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, USA
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  • For correspondence: benjamin.tenoever@mssm.edu
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Article Information

doi 
https://doi.org/10.1101/2020.03.24.004655
History 
  • March 24, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-ND 4.0 International license.

Author Information

  1. Daniel Blanco-Melo1,2,*,
  2. Benjamin E. Nilsson-Payant1,2,*,
  3. Wen-Chun Liu1,3,*,
  4. Rasmus Møller1,2,
  5. Maryline Panis1,2,
  6. David Sachs4,
  7. Randy A. Albrecht1,3,# and
  8. Benjamin R. tenOever1,2,3,#
  1. 1Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, USA
  2. 2Virus Engineering Center for Therapeutics and Research (VECToR), Icahn School of Medicine at Mount Sinai, New York, USA
  3. 3Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, USA
  4. 4Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, USA
  1. ↵#Corresponding author, email: benjamin.tenoever{at}mssm.edu
  1. ↵* Authors contributed equally

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Posted March 24, 2020.
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SARS-CoV-2 launches a unique transcriptional signature from in vitro, ex vivo, and in vivo systems
Daniel Blanco-Melo, Benjamin E. Nilsson-Payant, Wen-Chun Liu, Rasmus Møller, Maryline Panis, David Sachs, Randy A. Albrecht, Benjamin R. tenOever
bioRxiv 2020.03.24.004655; doi: https://doi.org/10.1101/2020.03.24.004655
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SARS-CoV-2 launches a unique transcriptional signature from in vitro, ex vivo, and in vivo systems
Daniel Blanco-Melo, Benjamin E. Nilsson-Payant, Wen-Chun Liu, Rasmus Møller, Maryline Panis, David Sachs, Randy A. Albrecht, Benjamin R. tenOever
bioRxiv 2020.03.24.004655; doi: https://doi.org/10.1101/2020.03.24.004655

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