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Hsp70 inhibits aggregation of Islet amyloid polypeptide by binding to the heterogeneous prenucleation oligomers

Neeraja Chilukoti, Bankanidhi Sahoo, S Deepa, Sreelakshmi Cherakara, Mithun Maddheshiya, View ORCID ProfileKanchan Garai
doi: https://doi.org/10.1101/2020.03.30.016881
Neeraja Chilukoti
1Tata Institute of Fundamental Research, 36/P Gopanpally, Serilingampally, Hyderabad 500019, India
2Centre for Cellular & Molecular Biology, Habsiguda, Hyderabad - 500 007
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Bankanidhi Sahoo
1Tata Institute of Fundamental Research, 36/P Gopanpally, Serilingampally, Hyderabad 500019, India
3Dr. Reddy’s Laboratories, Bachupally, Hyderabad 500090, India
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S Deepa
1Tata Institute of Fundamental Research, 36/P Gopanpally, Serilingampally, Hyderabad 500019, India
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Sreelakshmi Cherakara
1Tata Institute of Fundamental Research, 36/P Gopanpally, Serilingampally, Hyderabad 500019, India
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Mithun Maddheshiya
1Tata Institute of Fundamental Research, 36/P Gopanpally, Serilingampally, Hyderabad 500019, India
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Kanchan Garai
1Tata Institute of Fundamental Research, 36/P Gopanpally, Serilingampally, Hyderabad 500019, India
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  • ORCID record for Kanchan Garai
  • For correspondence: kanchan@tifrh.res.in
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Article Information

doi 
https://doi.org/10.1101/2020.03.30.016881
History 
  • March 31, 2020.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Neeraja Chilukoti1,2,
  2. Bankanidhi Sahoo1,3,
  3. S Deepa1,
  4. Sreelakshmi Cherakara1,
  5. Mithun Maddheshiya1 and
  6. Kanchan Garai1,*
  1. 1Tata Institute of Fundamental Research, 36/P Gopanpally, Serilingampally, Hyderabad 500019, India
  2. 2Centre for Cellular & Molecular Biology, Habsiguda, Hyderabad - 500 007
  3. 3Dr. Reddy’s Laboratories, Bachupally, Hyderabad 500090, India
  1. ↵*To whom correspondence should be addressed:
    Kanchan Garai, Email: kanchan{at}tifrh.res.in
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Posted March 31, 2020.
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Hsp70 inhibits aggregation of Islet amyloid polypeptide by binding to the heterogeneous prenucleation oligomers
Neeraja Chilukoti, Bankanidhi Sahoo, S Deepa, Sreelakshmi Cherakara, Mithun Maddheshiya, Kanchan Garai
bioRxiv 2020.03.30.016881; doi: https://doi.org/10.1101/2020.03.30.016881
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Hsp70 inhibits aggregation of Islet amyloid polypeptide by binding to the heterogeneous prenucleation oligomers
Neeraja Chilukoti, Bankanidhi Sahoo, S Deepa, Sreelakshmi Cherakara, Mithun Maddheshiya, Kanchan Garai
bioRxiv 2020.03.30.016881; doi: https://doi.org/10.1101/2020.03.30.016881

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