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High-affinity agonist binding to C5aR results from a cooperative two-site binding mechanism
Andra C. Dumitru, R. N. V. Krishna Deepak, Heng Liu, Melanie Koehler, Cheng Zhang, Hao Fan, View ORCID ProfileDavid Alsteens
doi: https://doi.org/10.1101/2020.04.03.024018
Andra C. Dumitru
1Université catholique de Louvain, Louvain Institute of Biomolecular Science and Technology, 1348 Louvain-la-Neuve, Belgium
R. N. V. Krishna Deepak
2Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore
Heng Liu
3Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA15261, USA
Melanie Koehler
1Université catholique de Louvain, Louvain Institute of Biomolecular Science and Technology, 1348 Louvain-la-Neuve, Belgium
Cheng Zhang
3Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA15261, USA
Hao Fan
2Bioinformatics Institute (BII), Agency for Science, Technology and Research (A*STAR), Singapore
David Alsteens
1Université catholique de Louvain, Louvain Institute of Biomolecular Science and Technology, 1348 Louvain-la-Neuve, Belgium
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Posted April 04, 2020.
High-affinity agonist binding to C5aR results from a cooperative two-site binding mechanism
Andra C. Dumitru, R. N. V. Krishna Deepak, Heng Liu, Melanie Koehler, Cheng Zhang, Hao Fan, David Alsteens
bioRxiv 2020.04.03.024018; doi: https://doi.org/10.1101/2020.04.03.024018
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