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Non-opioid analgesia based on Gα signalling bias
Mark J. Wall, Emily Hill, Robert Huckstepp, Giuseppe Deganutti, Michele Leuenberger, Barbara Preti, Kerry Barkan, Ian Winfield, Haifeng Wei, Wendy Imlach, Eve Dean, Cherise Hume, Stephanie Hayward, Jess Oliver, Fei-Yue Zhao, David Spanswick, Christopher A. Reynolds, Martin Lochner, View ORCID ProfileGraham Ladds, Bruno G. Frenguelli
doi: https://doi.org/10.1101/2020.04.04.023945
Mark J. Wall
1School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, UK
Emily Hill
1School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, UK
Robert Huckstepp
1School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, UK
Giuseppe Deganutti
2School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, UK
Michele Leuenberger
3Institute of Biochemistry and Molecular Medicine, University of Bern, 3012 Bern, Switzerland
Barbara Preti
3Institute of Biochemistry and Molecular Medicine, University of Bern, 3012 Bern, Switzerland
Kerry Barkan
4Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK
Ian Winfield
4Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK
Haifeng Wei
5NeuroSolutions Ltd, Coventry, UK
Wendy Imlach
6Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Innovation Walk, Clayton VIC 3800, Australia
Eve Dean
1School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, UK
Cherise Hume
1School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, UK
Stephanie Hayward
1School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, UK
Jess Oliver
1School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, UK
Fei-Yue Zhao
5NeuroSolutions Ltd, Coventry, UK
David Spanswick
5NeuroSolutions Ltd, Coventry, UK
6Department of Physiology, Monash Biomedicine Discovery Institute, Monash University, Innovation Walk, Clayton VIC 3800, Australia
7Warwick Medical School, University of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, UK
Christopher A. Reynolds
2School of Biological Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, UK
Martin Lochner
3Institute of Biochemistry and Molecular Medicine, University of Bern, 3012 Bern, Switzerland
Graham Ladds
4Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK
Bruno G. Frenguelli
1School of Life Sciences, University of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, UK
Posted April 05, 2020.
Non-opioid analgesia based on Gα signalling bias
Mark J. Wall, Emily Hill, Robert Huckstepp, Giuseppe Deganutti, Michele Leuenberger, Barbara Preti, Kerry Barkan, Ian Winfield, Haifeng Wei, Wendy Imlach, Eve Dean, Cherise Hume, Stephanie Hayward, Jess Oliver, Fei-Yue Zhao, David Spanswick, Christopher A. Reynolds, Martin Lochner, Graham Ladds, Bruno G. Frenguelli
bioRxiv 2020.04.04.023945; doi: https://doi.org/10.1101/2020.04.04.023945
Non-opioid analgesia based on Gα signalling bias
Mark J. Wall, Emily Hill, Robert Huckstepp, Giuseppe Deganutti, Michele Leuenberger, Barbara Preti, Kerry Barkan, Ian Winfield, Haifeng Wei, Wendy Imlach, Eve Dean, Cherise Hume, Stephanie Hayward, Jess Oliver, Fei-Yue Zhao, David Spanswick, Christopher A. Reynolds, Martin Lochner, Graham Ladds, Bruno G. Frenguelli
bioRxiv 2020.04.04.023945; doi: https://doi.org/10.1101/2020.04.04.023945
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